Results 31 to 40 of about 7,057 (208)
The mycobacterial desaturase DesA2 is associated with mycolic acid biosynthesis
Scientific Reports, 2022 Mycolic acids are critical for the survival and virulence of Mycobacterium tuberculosis, the causative agent of tuberculosis. Double bond formation in the merochain of mycolic acids remains poorly understood, though we have previously shown desA1 ...
Rebeca Bailo +5 more
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Mycolic acids. A reinvestigation
Journal of Biological Chemistry, 1978 Mycolic acids derived from the cell walls of Mycobacterium bovis BCG, Mycobacterium bovis Bovinus I, Mycobacterium smegmatis, and Mycobacterium tuberculosis H37Rv have been fractionated as their p-bromophenacyl esters by a two-step high performance liquid chromatographic procedure: 1) adsorption chromatography on 10-micrometer particle size silica gel,
P A, Steck +3 more
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Chemistry & Biology, 2008 The FabH enzyme from M. tuberculosis binds the acyl tail of large substrates at the end of a buried hydrophobic tunnel. Sachdeva et al. (2008) use reactive chemical probes and X-ray crystallography to show that substrates can bind to an open state of FabH without threading through the tunnel.
Lu, Jeff Zhiqiang, Prigge, Sean T.
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Mycolic Acids from “Noncultivable” Mycobacteria [PDF]
Infection and Immunity, 1974 Chromatographic analysis, coupled to mass spectrometry with a high-resolution mass spectrometer, of materials isolated from skin lesions of patients with lepromatous leprosy allows the recognition of characteristic mycobacterial products, mycolic acids. This finding indicates that the “noncultivable” bacteria responsible for leprosy are mycobacteria.
A H, Etemadi, J, Convit
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Journal of Lipid Research, 2009 Mycolic acids, the hallmark of mycobacteria and related bacteria, are major and specific components of their cell envelope and essential for the mycobacterial survival.
Elie Rafidinarivo +7 more
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Rv0132c of Mycobacterium tuberculosis encodes a coenzyme F420-dependent hydroxymycolic acid dehydrogenase. [PDF]
PLoS ONE, 2013 The ability of Mycobacterium tuberculosis to manipulate and evade human immune system is in part due to its extraordinarily complex cell wall. One of the key components of this cell wall is a family of lipids called mycolic acids.
Endang Purwantini, Biswarup Mukhopadhyay
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Fatty and mycolic acids of Mycobacterium malmoense [PDF]
Journal of Clinical Microbiology, 1988 The fatty acids and mycolic acids of 16 clinical isolates of Mycobacterium malmoense were studied by gas chromatography and thin-layer chromatography. All strains contained 2-methyleicosanoic and 2,4,6-trimethyltetracosanoic acids and alpha-, alpha'-, and keto-mycolic acids. The reported findings suggest that lipid analysis is a very useful approach in
P, Valero-Guillén +5 more
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PLoS ONE, 2007 BackgroundMycolic acids are a complex mixture of branched, long-chain fatty acids, representing key components of the highly hydrophobic mycobacterial cell wall. Pathogenic mycobacteria carry mycolic acid sub-types that contain cyclopropane rings. Double
Anuradha Alahari +8 more
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Extraction and Purification of Mycobacterial Mycolic Acids
Bio-Protocol, 2014 Mycolic acids are major long-chain fatty acids, containing up to 80-90 carbon atoms that represent essential components of the mycobacterial cell wall (Pawelczyk and Kremer, 2014).
Christian Dupont, Laurent Kremer
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Mycolic Acids of Mycobacterium porcinum [PDF]
International Journal of Systematic Bacteriology, 1987 The type strain of Mycobacterium porcinum had a characteristic pattern of α-, α'-, and epoxymycolic acids. This pattern of mycolic acids has been found previously only in representatives of M. farcinogenes, M. fortuitum, “M. peregrinum,” M. senegalense, M. smegmatis, and M. chitae.
M. Luquin +3 more
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