Results 161 to 170 of about 58,596 (215)

Activation of the NF‐ĸB Signaling Pathway by Lactobacillus plantarum and Lactobacillus casei Through Modulation of TLR4 and DC‐SIGN Genes in an Oral Squamous Cell Carcinoma Rat Model

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background The composition of the oral and intestinal microbiota is believed to contribute to the development of oral cancer (OC). The chronic activation of pattern recognition receptors (PRRs) has been linked to the aggressive nature and poor prognosis of various cancers.
Vahideh Faghanizadeh, Malihe Naderi, Nazila Arbab Soleimani, Ayyoob Khosravi, Mohammad Mahdi Forghanifard   +4 more
wiley   +1 more source

IRAK4 autophosphorylation functions as a molecular switch to regulate death domain assembly and Myddosome maturation

Taylor M, Srikanth N, Deliz-Aguirre R, Gola DK, Bilay M, Ziska E, Kelsall I, Kukathu Y.   +7 more
europepmc   +1 more source

Enhanced Epigenetic Modulation via mRNA-Encapsulated Lipid Nanoparticles Enables Targeted Anti-inflammatory Control. [PDF]

ACS Synth Biol
Mokhtari T, Taheri MN, Akhlaghi S, Aryannejad A, Xiang Y, Mahajan V, Keshavarz K, Kiani A, Yang S, LoPresti S, LeGraw R, Whitehead KA, Kiani S.   +12 more
europepmc   +1 more source

Adverse Prognostic Significance of Activation‐Induced Cytidine Deaminase in Diffuse Large B‐Cell Lymphoma Patients Treated With R‐CHOP

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background A number of studies have demonstrated the important role of activation‐induced cytidine deaminase (AID) in the pathogenesis of diffuse large B‐cell lymphoma (DLBCL). AID has been relatively underexplored as a prognostic factor in DLBCL, and its role remains controversial.
Mardiah Suci Hardianti, Nungki Anggorowati, Syahru Agung Setiawan, Miraz Radhea Bagaskoro, Johan Kurnianda, Kartika Widayati Taroeno‐Hariadi, Ibnu Purwanto, Susanna Hilda Hutajulu   +7 more
wiley   +1 more source

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells. [PDF]

Immunology
Si W, Zhu G, Jiang Q, Ma X, Yang G.
europepmc   +1 more source

Secoisolariciresinol Diglucoside Alleviates LPS‐Induced Acute Lung Injury by Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are life‐threatening pulmonary disorders with high mortality rates, and effective treatments are currently lacking. Secoisolariciresinol diglucoside (SDG), a plant lignan derived from flaxseed, possesses anti‐inflammatory and antioxidative activities.
Yuanyuan Zhong, Yang Zou, Zhen Qu, Kai Zhou, Huijuan Liu, Jiali Yang, Chengzhong Tang, Yuqiang Xu, Zhen Wang   +8 more
wiley   +1 more source

Systems-Level Analysis of HPAI H5N1 Infection in Ducks: Integrating Transcriptomic, Proteomic, and Phosphoproteomic Data. [PDF]

Int J Mol Sci
Vijayakumar P, Mishra A, Rajamanickam K, Raut AA.   +3 more
europepmc   +1 more source

Borrelia burgdorferi sensu lato Employs Several Escape Mechanisms to Bypass the Human Defense System

European Journal of Immunology, Volume 56, Issue 5, May 2026.
Integrated overview of host defense and immune evasion in Lyme Borreliosis. Bbsl evades immunity through tick saliva‐mediated suppression of innate defenses, TLR2/NOD2‐driven cytokine dysregulation, and interference with JAK/STAT and CIITA‐dependent antigen presentation.
Zara Karami, Hadewych J. M. ter Hofstede, Leo A. B. Joosten   +2 more
wiley   +1 more source

Treatment initiation by positive liquid biopsy alone in primary central nervous system lymphoma: A retrospective analysis of a multi-institutional study. [PDF]

Neurooncol Adv
Mitobe M, Shibuma S, Takahashi H, On J, Takino T, Kawabe K, Mouri Y, Kumagai S, Kozakai T, Momoi A, Suzuki N, Fukushima T, Suzuki T, Kuroda H, Saji E, Nakamura K, Hashidate H, Nakahara A, Tomita T, Watanabe J, Tsukamoto Y, Okada M, Hiraishi T, Yamashita S, Akai T, Kuroda S, Kakita A, Sone H, Takizawa J, Oishi M, Natsumeda M.   +30 more
europepmc   +1 more source