Results 161 to 170 of about 85,956 (299)

Cutaneous lymphomas – an update

Histopathology, EarlyView.
Primary cutaneous lymphomas and lymphoproliferative disorders are defined by integrated clinical, histopathological, immunophenotypic and genetic features as diagnostic criteria also in the 5th edition of the WHO classification of haematolymphoid tumors.
Werner Kempf, Christina Mitteldorf
wiley   +1 more source

TLR Signaling Beyond Immunity: Emerging Roles in Cell Migration, Metabolism, Development, and Host-Microbiome Crosstalk. [PDF]

Biology (Basel)
Liu L, Spaink HP.
europepmc   +1 more source

Allergen Protease Act d 1 Induces TLR4‐Dependent Inflammation via Ectodomain Cleavage

Allergy, EarlyView.
Milena Zlatanova, Iva Hafner‐Bratkovič, Marija Gavrović‐Jankulović   +2 more
wiley   +1 more source

Investigation of IgM Monoclonal Paraprotein in Bone Marrow Aspiration: The Role of Immunophenotyping by Flow Cytometry in Selecting Cases for Molecular Testing for the p.MYD88 L265P Point Mutation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Flow cytometry and real‐time quantitative polymerase chain reaction (qRT‐PCR) for MYD88 mutations (MYD88mt) are routinely performed on bone marrow aspirates during the diagnostic evaluation of IgM monoclonal paraproteinemia. The potential predictive value of immunophenotypic findings for molecular results, however, remains to be ...
Georgios Boutsikas, Konstantinos Agiannitopoulos, Elisavet Kouvidi, Myrto Katraki, Athanasios Papatheodorou, Anna Roussou, Nikolaos Paschalidis, Theodoros P. Vassilakopoulos, Ioannis Anagnostopoulos, Dimitra Sasaroli, Aglaia Dimitrakopoulou   +10 more
wiley   +1 more source

E3 ubiquitin ligase Smurf1 facilitates bacterial infection and regulates inflammatory responses via promoting MyD88 degradation in teleost. [PDF]

Zool Res
Dong W, Xu T, Sun Y.
europepmc   +1 more source

Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines

Immunology, EarlyView.
This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw, Aytenew Atnaf, Bantayehu Addis Tegegne, Abebe Fenta, Bantegzie Selabat, Temesgen Baylie, Yonatan Kindie, Zigale Hibstu Teffera, Mekuriaw Belayneh, Mohammed Jemal, Adane Adugna   +10 more
wiley   +1 more source

Blocking MyD88 Signaling Pathway Protects Against Myocardial Ischemia Reperfusion by Inhibiting NOX/ROS Pathway and Enhancing eNOS Activity. [PDF]

Int J Mol Sci
Wang B, Huang X, Xie L.
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

2-O, 3-O Desulfated Heparin (ODSH) Preserves Endothelial Barrier Integrity in Lipopolysaccharide-Induced Acute Lung Injury by Modulating TLR4-MyD88-NF-κB Signaling. [PDF]

Biomolecules
Patil RS, Patil SR, Simon L, Biggs P, Jaiswal L, Mohamed B, Kennedy TP, Gonzales J, Verin AD.   +8 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source