Results 171 to 180 of about 85,956 (299)

Anti-Nectin4 monoclonal antibodies attenuate airway inflammation and epithelial barrier dysfunction in asthma. [PDF]

Front Pharmacol
Lee PH, An M, Yoon S, Jang AS.
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Protective effect of hesperetin against myelosuppression and splenic inflammation via modulating TLR4/MYD88/NF-κB signaling: molecular docking and experimental validation. [PDF]

Front Pharmacol
Badawi GA, Abdelmaogood AKK, Ahmed N, Rohayem S, Fawzy S, Zaitone SA, Aldahish AA, Abdelkhalig SM, Helal MA, Mohamed NM, Al-Najjar AH.   +10 more
europepmc   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.

New England Journal of Medicine, 2012
S. Treon, Lian Xu, Guang Yang, Yangsheng Zhou, Xia Liu, Yang-Lin Cao, P. Sheehy, R. Manning, C. Patterson, C. Tripsas, L. Arcaini, G. Pinkus, S. Rodig, A. Sohani, N. Harris, J. Laramie, D. Skifter, S. Lincoln, Z. Hunter   +18 more
semanticscholar   +1 more source

SAMSN1 restricts Japanese encephalitis virus replication by recruiting TRIM21 to degrade viral proteins and activate the interferon pathway. [PDF]

Vet Res
Wang C, Qin W, Wang X, Yang X, Tong W, Yu H, Tong G, Shan T, Kong N, Xing G, Zheng H.   +10 more
europepmc   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source

Sesamin suppresses high glucose-induced cyclooxygenase-2 and prostaglandin E₂ production through Toll-like receptor 2-dependent oxidative stress in human gingival fibroblasts. [PDF]

J Dent Sci
Li YL, Hsu YC, Fan FY, Wang YL, Wu YC, Li SY, Vo TTT, Chang YC, Shih YT, Lee IT.   +9 more
europepmc   +1 more source

MYD88 wt Allele [PDF]

, 2020
openaire   +1 more source