This study showed dysregulated αβ T cell homeostasis with ongoing T cell activation and low‐grade inflammation in 5‐12‐year‐old CHD children who underwent early‐life cardiac surgery with thymectomy, characterized by reduced naïve T cells and increased memory/effector and senescent‐like T cells.
Yusuf Eshimutu Abu +13 more
wiley +1 more source
Anti-Inflammatory Effects of Pingyin Rose Essential Oil in LPS-Induced HaCaT Cells: An in Vitro and in Silico Study. [PDF]
Song J +5 more
europepmc +1 more source
MyD88 signaling in myeloid cells induces gastrointestinal tract injury and systemic inflammation after West Nile virus infection. [PDF]
Lin SC +4 more
europepmc +1 more source
Inhibition of TLR4 enhances oxaliplatin chemotherapy sensitivity in esophageal squamous cell carcinoma by suppressing inflammation and glycolysis. [PDF]
Zhu Z +6 more
europepmc +1 more source
3'-hydroxypuerarin mitigates LPS-induced acute lung injury by inhibiting TLR4 activation-mediated NF-κB p65/NLRP3/GSDMD signaling. [PDF]
Hu H +7 more
europepmc +1 more source
Ningxiang pig-derived Enterococcus hirae protects against E. coli-induced gut dysbiosis and inflammation via acetate/propionate-MyD88-NF-κB axis in piglets. [PDF]
Zhang L +10 more
europepmc +1 more source
Evodiamine alleviates MPTP-induced Parkinson's disease in mice by regulating gut microbiota and suppressing TLR4/MyD88/NF-kB pathway. [PDF]
Wang S +8 more
europepmc +1 more source
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MYD88 L265P mutation in Waldenstrom macroglobulinemia
Blood, 2013Key Points The MYD88 locus is altered in 91% of patients with WM. MYD88 might be new target for therapeutic in WM.
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Mycobacterial Infection in MyD88‐Deficient Mice
Microbiology and Immunology, 2003AbstractMyD88 is an adaptor protein that plays a major role in TLR/IL‐1 receptor family signaling. To understand the role of MyD88 in the development of murine tuberculosis in vivo, MyD88 knockout (KO) mice aerially were infected with Mycobacterium tuberculosis. Infected MyD88 mice were not highly susceptible to M.
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