Results 211 to 220 of about 105,796 (273)

Association of Toll-like receptor signaling molecule gene polymorphisms with risk of cervical lesions in HPV-infected women. [PDF]

BMC Infect Dis
Wang S, Zhang C, Li T, Luo P, Yang Y, Lin Z, Mei B.   +6 more
europepmc   +1 more source

Multi‐Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Gestational diabetes mellitus (GDM), a common pregnancy complication characterized by maternal hyperglycemia, negatively impacts offspring health. Skeletal muscle, a critical tissue for glucose and lipid metabolism, is especially vulnerable to prenatal environmental insults.
Rui Liu, Junsen She, Xinyuan Li, Yishang Yan, Jiaying Mo, Jianzhong Sheng, Hongbo Yang, Hefeng Huang   +7 more
wiley   +1 more source

Spike protein-induced VSIR-ISX signaling disrupts metabolic homeostasis and promotes COVID-19-related immune dysfunction. [PDF]

Cell Biol Toxicol
Wang LT, Wang SN, Chiou SS, Chai CY, Hsu SH.   +4 more
europepmc   +1 more source

Intranasal Human NSC‐Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS‐STING Signalling, in Aged Hippocampus

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
ABSTRACT Neuroinflammaging, a moderate, chronic, and sterile inflammation in the hippocampus, contributes to age‐related cognitive decline. Neuroinflammaging comprises the activation of the nucleotide‐binding domain, leucine‐rich repeat family, and pyrin domain‐containing 3 (NLRP3) inflammasomes, and the cyclic GMP‐AMP synthase (cGAS)‐stimulator of ...
Leelavathi N. Madhu, Maheedhar Kodali, Shama Rao, Sahithi Attaluri, Raghavendra Upadhya, Goutham Shankar, Bing Shuai, Yogish Somayaji, Shruthi V. Ganesh, Vignesh S. Kumar, Jeswin E. James, Padmashri A. Shetty, Avery LeMaire, Xiaolan Rao, James J Cai, Ashok K. Shetty   +15 more
wiley   +1 more source

Bicuculline from <i>Forsythia suspensa</i> attenuates liver fibrosis via TLR4/MD2 inhibition and suppression of MyD88/NF-κB signaling. [PDF]

Comput Struct Biotechnol J
Zhang X, Wu G, Peng S, Xu H, Li K, Huang T, Liu Z.   +6 more
europepmc   +1 more source

Atg5 regulates formation of MyD88 condensed structures and MyD88-dependent signal transduction.

Atg5 regulates formation of MyD88 condensed structures and MyD88-dependent signal transduction.
MyD88 is known as an essential adaptor protein for Toll-like receptors (TLRs). Previous studies have shown that transfected MyD88 forms condensed structures in the cytoplasm. However, upon TLR stimulation, there is little formation of endogenous MyD88 condensed structures. Thus, the formation of MyD88 condensed structures is tightly suppressed, but the
openaire  

Activating MYD88 Gene Mutation [PDF]

, 2020
openaire   +1 more source

Protection of goose adiponectin-derived peptide gADP3 on LPS-induced thymus and spleen injury in goose. [PDF]

Poult Sci
Ma B, Cao Z, Yao Z, Zheng Y, Gao M, Luan X.   +5 more
europepmc   +1 more source

Hemophagocytic Lymphohistiocytosis as First Manifestation of Dual B‐Cell Neoplasms: A Case Report of Co‐Existing Multiple Myeloma and B‐Cell Lymphoma

eJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is an immune disorder causing excessive inflammation and tissue damage. Lymphoma, especially T‐cell lymphoma, is the most common cause of HLH, while Multiple Myeloma (MM) is rarely associated. We present a 61‐year‐old man with spiking fevers, fatigue, and unintentional weight loss. The HLH was driven by
Carla Romagnoli, Alexandra Lyubimova, Leily Santos‐Carrion, Ferial Alloush, Vathany Sriganeshan, Andrea Noboa, Jacqueline C. Barrientos   +6 more
wiley   +1 more source

Exploratory study on the efficacy of Lingze mixture in gouty arthritis rats and preliminary analysis of its potential mechanisms via transcriptome sequencing. [PDF]

Sci Rep
Liu J, Chen Y, Zhao Y, Kong D, Ma B, Gan Y, Qiao M, Bao Y, Fang X, Zhu J, Ming C, Wei H, Yang D, Han C, Gao Z, Wang H.   +15 more
europepmc   +1 more source