Results 221 to 230 of about 105,796 (273)

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Uncovering regulatory B-cell features associated with regulatory T-cell expansion and global T-cell exhaustion in Waldenström macroglobulinemia <i>Myd88</i> ^<i>L252P</i> -like lymphoplasmacytic lymphomas. [PDF]

Hemasphere
Lemasson Q, Tabaud M, Téteau O, Carle B, Chabaud M, Feuillard J, Faumont N, Vincent-Fabert C.   +7 more
europepmc   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Modulation of Toll-like Receptors with Natural Compounds: A Therapeutic Avenue Against Inflammaging? [PDF]

Int J Mol Sci
Andrei C, Pușcașu C, Nitulescu GM, Zanfirescu A.   +3 more
europepmc   +1 more source

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, Volume 59, Issue 2, February 2026.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source

Cathelicidin-Ka, the first frog-derived TLR2 and TLR4 agonist, induces macrophage activation and promotes inflammation. [PDF]

Cell Mol Life Sci
Chai J, Wu J, Zhang S, Zhang W, Xiong W, Li J, Nguyen T, Shu L, Kotsyfakis M, Chen X, Xu X.   +10 more
europepmc   +1 more source

Primary Cutaneous B‐Cell Lymphomas: An Updated Portrait of Classification, Biology, and Clinical Management

European Journal of Haematology, Volume 116, Issue 2, Page 116-128, February 2026.
ABSTRACT Primary cutaneous B‐cell lymphomas (CBCL) represent a clinically and biologically heterogeneous group of extranodal non‐Hodgkin lymphomas confined to the skin at the time of diagnosis. They account for approximately 25% of all primary cutaneous lymphomas and are subclassified into distinct entities according to the World Health Organization ...
A. Bernardelli, E. Carazzai, B. Bugnotto, F. Bellinato, M. Krampera, C. Visco   +5 more
wiley   +1 more source

MyD88 Contributes to TLR3-Mediated NF-κB Activation and Cytokine Production in Macrophages. [PDF]

Cells
Chai Z, Zhou Y, Yang L, Zhang Y, Hossain S, Hajimirzaei S, Qi J, Zhang G, Wei Y, Li Z.   +9 more
europepmc   +1 more source

Cortisol Regulates PD‐1 and IL‐12 in Canine Leishmaniasis

Parasite Immunology, Volume 48, Issue 2, February 2026.
ABSTRACT Canine visceral leishmaniasis (CanL) is a tropical zoonosis caused by Brazil's protozoan Leishmania (L.) infantum. Disorders in the hypothalamic–pituitary–adrenal (HPA) axis have been reported in human and experimental visceral leishmaniasis, but not yet in canine leishmaniasis.
Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Mayla Abbas Guimarães, Bianca Maciel Marques de Souza, Sofia Furrier Soares, Luiz Eduardo Amador Loiola Pereira, Valéria Marçal Felix de Lima   +6 more
wiley   +1 more source

Multiple Signaling Axes (TNF-α/IL1β/IL8, TLR4/MYD88/NF-κB, and TGF-β1/ROS) Associated With Coronary Collateral Circulation of Coronary Chronic Total Occlusion in Geriatric Patients. [PDF]

Mediators Inflamm
Zhao Y, Zhou H, Chen Y, Guo D.
europepmc   +1 more source