Results 101 to 110 of about 188,742 (365)
Cerebral Cortex, 2017 Research in the macaque monkey suggests that cortical areas with similar microstructure are more likely to be connected. Here, we examine this link in the human cerebral cortex using 2 magnetic resonance imaging (MRI) measures: quantitative T1 maps ...
Julia M. Huntenburg +5 more
semanticscholar +1 more source
Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration
Advanced Therapeutics, EarlyView.Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana +5 more
wiley +1 more source
Frontiers in Aging Neuroscience, 2018 This review proposes that lipopolysaccharide (LPS, found in the wall of all Gram-negative bacteria) could play a role in causing sporadic Alzheimer’s disease (AD). This is based in part upon recent studies showing that: Gram-negative E. coli bacteria can
Xinhua Zhan +2 more
doaj +1 more source
Novel Treatment Strategies Targeting Myelin and Oligodendrocyte Dysfunction in Schizophrenia
Frontiers in Psychiatry, 2020 Oligodendrocytes are the glial cells responsible for the formation of the myelin sheath around axons. During neurodevelopment, oligodendrocytes undergo maturation and differentiation, and later remyelination in adulthood. Abnormalities in these processes
Danielle Gouvêa-Junqueira +9 more
doaj +1 more source
Oligodendrocytes express synaptic proteins that modulate myelin sheath formation
Nature Communications, 2019 Vesicular release from neurons promotes myelin sheath growth on axons. Oligodendrocytes express proteins that allow dendrites to respond to vesicular release at synapses, suggesting that axon-myelin contacts use similar communication mechanisms as ...
Alexandria N. Hughes, B. Appel
semanticscholar +1 more source
α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model
Advanced Science, EarlyView.A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro +14 more
wiley +1 more source
Neurobiology of Disease, 2022 Impaired bioenergetic capacity of the nervous system is thought to contribute to the pathogenesis of many neurodegenerative diseases (NDD). Since neuronal synapses are believed to be the major energy consumers in the nervous system, synaptic derangements
Bogdan Beirowski
doaj
Confined Multilamellae Prefer Cylindrical Morphology [PDF]
arXiv, 2005 By evaporating a drop of lipid dispersion we generate the myelin morphology often seen in dissolving surfactant powders. We explain these puzzling nonequilibrium structures using a geometric argument: The bilayer repeat spacing increases and thus the repulsion between bilayers decreases when a multilamellar disk is converted into a myelin without gain ...
arxiv
Myelin sheath structure and regeneration in peripheral nerve injury repair
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Afferent and efferent nerve fibers cannot be distinguished based on the axonal diameter or the presence of the Remark bundle. The compaction of the myelin sheath involves 2 steps: 1) The distance between the 2 layers of cell membranes in the
B. Liu +15 more
semanticscholar +1 more source
Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
Advanced Science, EarlyView.This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng +8 more
wiley +1 more source