Results 131 to 140 of about 188,742 (365)

Intrinsic dynamical fluctuations of PNS myelin [PDF]

arXiv, 2017
The ultrastructure fluctuations and complex dynamics of the multi-layered membrane structure of myelin are fundamental for understanding and control its formation process and its degeneration and repair in neurological diseases such as multiple sclerosis (MS).
arxiv  

Myelin Dynamics Throughout Life: An Ever-Changing Landscape?

Frontiers in Cellular Neuroscience, 2018
Myelin sheaths speed up impulse propagation along the axons of neurons without the need for increasing axon diameter. Subsequently, myelin (which is made by oligodendrocytes in the central nervous system) allows for highly complex yet compact circuitry ...
Jill M Williamson, D. Lyons
semanticscholar   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

Myelin histology: a key tool in nervous system research

Neural Regeneration Research
The myelin sheath is a lipoprotein-rich, multilayered structure capable of increasing conduction velocity in central and peripheral myelinated nerve fibers. Due to the complex structure and composition of myelin, various histological techniques have been
Óscar Darío García-García, Víctor Carriel, Jesús Chato-Astrain   +2 more
doaj   +1 more source

Cell vibron polariton in the myelin sheath of nerve [PDF]

arXiv, 2019
Polaritons are arousing tremendous interests in physics and material sciences for their unique and amazing properties, especially including the condensation, lasing without inversion and even room-temperature superfluidity. Herein, we propose a cell vibron polariton (cell-VP): a collectively coherent mode of a photon and all phospholipid molecules in a
arxiv  

Myelin phagocytosis by astrocytes after myelin damage promotes lesion pathology

Brain : a journal of neurology, 2017
Astrocytes are key players in the pathology of multiple sclerosis and can assume beneficial and detrimental roles during lesion development. The triggers and timing of the different astroglial responses in acute lesions remain unclear.
G. Ponath, S. Ramanan, M. Mubarak, William J. Housley, Seunghoon Lee, F. Rezan Sahinkaya, A. Vortmeyer, Cedric S. Raine, D. Pitt   +8 more
semanticscholar   +1 more source

A Facile Strategy to Restore the Optic Nerve Functionality Using an Injectable Conducting Hydrogel

Advanced Science, EarlyView.
An injectable conductive polymer hydrogel from poly (3,4‐ethylenedioxythiophene) (PEDOT) is developed to facilitate the recovery of electrophysiological function in injured optic nerve. The hydrogel can be injected directly at the injury site and spontaneously gel in place.
Changchun Yu, Yandi Zhou, Shuang Yao, Ziyi Wang, Sihao Ye, Rubing Qi, Hai Hu, Keke Liu, Yabo Wu, Tom Lawson, Lu Yan, Yong Liu, Wencan Wu   +12 more
wiley   +1 more source

A computed tomography‐based survey of paramedullary diverticula in extant Aves

The Anatomical Record, Volume 306, Issue 1, Page 29-50, January 2023., 2023
Abstract Avian respiratory systems are comprised of rigid lungs connected to a hierarchically organized network of large, regional air sacs, and small diverticula that branch from them. Paramedullary diverticula are those that rest in contact with the spinal cord, and frequently invade the vertebral canal.
Jessie Atterholt, Mathew J. Wedel
wiley   +1 more source

The microglial "activation" continuum: from innate to adaptive responses

Journal of Neuroinflammation, 2005
Microglia are innate immune cells of myeloid origin that take up residence in the central nervous system (CNS) during embryogenesis. While classically regarded as macrophage-like cells, it is becoming increasingly clear that reactive microglia play more ...
Nikolic Veljko, Town Terrence, Tan Jun
doaj   +1 more source

The signal synchronization function of myelin [PDF]

arXiv
The myelinated axons are widely present in both central and peripheral nervous systems. Its unique compact spiraling structure poses significant challenges to understanding its biological functions and developmental mechanisms. Conventionally, myelin is considered as an insulating layer to achieve saltatory conduction for the enhancement of the neural ...
arxiv