Results 141 to 150 of about 300,317 (388)

Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. [PDF]

, 2018
Binding of small molecules in the human leukocyte antigen (HLA) peptide-binding groove may result in conformational changes of bound peptide and an altered immune response, but previous studies have not considered a potential role for endogenous ...
Damotte, Vincent, Hollenbach, Jill, Misra, Maneesh   +2 more
core   +1 more source

Reply to Letter: “Real‐World Clinical Experience With Serum MOG and AQP4 Antibody Testing by Live Versus Fixed Cell‐Based Assay”

Annals of Clinical and Translational Neurology, EarlyView.
Yana Said, Eoin P. Flanagan, Elias S. Sotirchos   +2 more
wiley   +1 more source

A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun, Ozgu Kizek, Sibel Aylin Ugur Iseri, Ibrahim Kamaci, Ayse Deniz Elmali, Pinar Iscen, Berfin Gulkaya Guzel, Gul Yalcin Cakmakli, Bulent Elibol, Berril Donmez, Raif Cakmur, Pinar Topaloglu, Turkish NBIA Study Group, Abdullah Acar, Ahmet Acarer, Arzu Karabay, Asuman Ali, Ayla Barlas, Aysegul Gunduz, Banu Ozen Barut, Baris Baslo, Bilge Kocer, Bilgehan Mus, Birsen Karaman, Burcu Gokce Cokal, Cem Ismail Kucukali, Cenk Akbostanci, Ceyhun Sayman, Cagla Turan, Dilek Ince Gunal, Ebru Bilge Dirik, Ebru Erzurumluoglu, Elif Kocasoy Orhan, Enes Demiryurek, Emrah Yucesan, Ercan Kose, Erdem Tuzun, Esen Saka Topcuoglu, Esra Okuyucu, Fatma Betul Ozdilek, Feriha Ozer, Gencer Genc, Gozde Unal, Gulay Kenangil, Gullu Tarhan, Gunes Kiziltan, Halil Onder, Hamit Genc, Hasmet Hanagasi, Hatice Yuksel, Hulya Apaydin, Koray Kirimtay, Mehmet Guney Senol, Melisa Kilic, Meltem Demirkiran, Mert Karaca, Miray Erdem, Muhammet Bilgehan Mus, Murat Gultekin, Nalan Capan, Nazan Karagoz Sakalli, Nazli Basak, Nihan Hande Akcakaya, Ozan Ezer, Ozge Uygun, Ozge Yilmaz Kuspeci, Ozgur Oztop Cakmak, Pervin Iseri, Petek Ballar Kirmizibayrak, Pinar Elkoca, Recep Alp, Remzi Yigiter, Rezzak Yilmaz, Sadika Ozdemir, Selda Keskin, Selen Ilhan Alp, Selen Soylu, Serdar Ceylaner, Serhat Ozkan, Sevda Erer Ozbek, Sevgin Gundogan, Sevil Yasufli, Sezin Alpaydin Baslo, Sibel Ertan, Sultan Cagirici, Seyma Aykac, Vuslat Yilmaz, Yaprak Secil, Yasar Kutukcu, Yeliz Ciftci, Yesim Sucullu Karadag, Yildiz Değirmenci, Zeliha Matur, Nerses Bebek, Murat Emre, Zuhal Yapici   +95 more
wiley   +1 more source

Reflective imaging of myelin integrity in the human and mouse central nervous systems

Frontiers in Cellular Neuroscience
The structural integrity of myelin sheaths in the central nervous system (CNS) is crucial for the maintenance of its function. Electron microscopy (EM) is the gold standard for visualizing individual myelin sheaths.
Georgina A. Craig, Georgina A. Craig, Lucy Ryan, Jessica Thapar, Niamh B. McNamara, Alana Hoffmann, Alana Hoffmann, Danielle Page, Jamie Rose, Simon R. Cox, Veronique E. Miron, Veronique E. Miron, Veronique E. Miron   +12 more
doaj   +1 more source

Influence of Mechanical Stimuli on Schwann Cell Biology

Frontiers in Cellular Neuroscience, 2017
Schwann cells are the glial cells of the peripheral nervous system (PNS). They insulate axons by forming a specialized extension of plasma membrane called the myelin sheath.
Sophie Belin, Kristen L. Zuloaga, Yannick Poitelon   +2 more
doaj   +1 more source

Myelin-oligodendrocyte glycoprotein antibody-associated disease

Lancet Neurology, 2021
R. Marignier, Y. Hacohen, Á. Cobo-Calvo, A. Pröbstel, O. Aktas, H. Alexopoulos, Mary Amato, N. Asgari, B. Banwell, J. Bennett, F. Brilot, M. Capobianco, T. Chitnis, O. Ciccarelli, K. Deiva, J. Seze, K. Fujihara, A. Jacob, H. Kim, I. Kleiter, H. Lassmann, M. Leite, C. Linington, E. Meinl, Jacqueline Palace, Friedemann Paul, A. Petzold, S. Pittock, M. Reindl, D. Sato, K. Selmaj, A. Siva, B. Stankoff, M. Tintoré, A. Traboulsee, P. Waters, E. Waubant, B. Weinshenker, T. Derfuss, S. Vukusic, Bernhard Hemmer   +40 more
semanticscholar   +1 more source

Oligodendrocytes express synaptic proteins that modulate myelin sheath formation

Nature Communications, 2019
Vesicular release from neurons promotes myelin sheath growth on axons. Oligodendrocytes express proteins that allow dendrites to respond to vesicular release at synapses, suggesting that axon-myelin contacts use similar communication mechanisms as ...
Alexandria N. Hughes, B. Appel
semanticscholar   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Understanding Brain Plasticity in Learning Process

International Journal of Research in STEM Education, 2020
Brain plasticity takes an essential part in the learning process and memory retaining. Brain plasticity is connected with myelin sheath development and oligodendrocyte plasticity.
Yuliana Yuliana
doaj   +1 more source

A Systematic Relationship Between Functional Connectivity and Intracortical Myelin in the Human Cerebral Cortex

Cerebral Cortex, 2017
Research in the macaque monkey suggests that cortical areas with similar microstructure are more likely to be connected. Here, we examine this link in the human cerebral cortex using 2 magnetic resonance imaging (MRI) measures: quantitative T1 maps ...
Julia M. Huntenburg, P. Bazin, A. Goulas, Christine L. Tardif, A. Villringer, D. Margulies   +5 more
semanticscholar   +1 more source