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Morphology of Myelin and Myelination
1984Myelin is a membrane characteristic of nervous tissue, laid down in segments along selected nerve fibers, that functions as an insulator to increase the velocity of stimuli being transmitted between a nerve-cell body and its target. While well documented in several invertebrates (annelids and crustaceans) in which it exists in its peripheral nervous ...
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Myelinated Nerve Fibre, Myelin
2010Nerve fibres designed for particularly rapid and efficient conduction of action potentials are equipped with a myelin sheath, a lipid-enriched layer, produced by specialised glial cells, the oligodendrocytes in the central nervous system, and the Schwann cells in the peripheral nervous system.
Jürgen Roth, Margit Pavelka
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Current Protocols in Cell Biology, 2006
AbstractThe methods used to prepare myelin involve homogenization of the tissue in isotonic sucrose solution, followed by the isolation of myelin membranes by a series of steps that include density gradient centrifugation and differential centrifugation. Homogenization of nervous tissue in isotonic sucrose causes the myelin sheath to peel from the axon
Williams T. Norton, Jorge N. Larocca
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AbstractThe methods used to prepare myelin involve homogenization of the tissue in isotonic sucrose solution, followed by the isolation of myelin membranes by a series of steps that include density gradient centrifugation and differential centrifugation. Homogenization of nervous tissue in isotonic sucrose causes the myelin sheath to peel from the axon
Williams T. Norton, Jorge N. Larocca
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1997
Although it is well known that the central nervous system (CNS) and the peripheral nervous system (PNS), and in particular their myelin, contain large quantities of cholesterol, the specific role of this lipid in the structure and function of the nervous system remains elusive. In this review, we will summarize progress in our understanding of the role
Ueli Suter, G. Jackson Snipes
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Although it is well known that the central nervous system (CNS) and the peripheral nervous system (PNS), and in particular their myelin, contain large quantities of cholesterol, the specific role of this lipid in the structure and function of the nervous system remains elusive. In this review, we will summarize progress in our understanding of the role
Ueli Suter, G. Jackson Snipes
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Immunological Responses to Myelin and Myelin Components [PDF]
, 1977 The majority of the data available on the immunology of central nervous system (CNS) myelin relate to the specificity of myelin, and in particular its basic protein component, in bringing about the clinical signs and histopathologically defined lesions characteristic of experimental allergic encephalomyelitis (EAE) via a primarily cell-mediated ...
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Neurologic Clinics, 1995
Although it was initially thought to be a passive structure, the oligodendrocyte and myelin unit is now considered highly dynamic with many important functions beyond its role in myelination. Inhibitors of neurite growth can be localized to oligodendrocyte and myelin, highlighting the importance of oligodendrocytes in general CNS maintenance and in ...
JoAnne McLaurin, Voon Wee Yong
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Although it was initially thought to be a passive structure, the oligodendrocyte and myelin unit is now considered highly dynamic with many important functions beyond its role in myelination. Inhibitors of neurite growth can be localized to oligodendrocyte and myelin, highlighting the importance of oligodendrocytes in general CNS maintenance and in ...
JoAnne McLaurin, Voon Wee Yong
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The development of myelin and myelin-related cells
Trends in Neurosciences, 1981Abstract Myelin-related cells (Schwann cells and oligodendrocytes) co-operate with the axon in the formation and maintenance of myelin sheaths. Our understanding of the control of numbers and function of these cells is advancing rapidly; surprisingly, substantial differences between the biology of PNS and CNS myelin are coming to light.
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Magnetic Resonance of Myelin, Myelination, and Myelin Disorders
Radiology, 1990openaire +2 more sources