Results 61 to 70 of about 113,980 (171)

Natural electromagnetic waveguide structures based on myelin sheath in the neural system [PDF]

open access: yesarXiv, 2012
The saltatory propagation of action potentials on myelinated axons is conventionally explained by the mechanism employing local circuit ionic current flows between nodes of Ranvier. Under this framework, the myelin sheath with up to 100 layers of membrane only serves as the insulating shell.
arxiv  

The history of myelin [PDF]

open access: yesExperimental Neurology, 2016
Andreas Vesalius is attributed the discovery of white matter in the 16th century but van Leeuwenhoek is arguably the first to have observed myelinated fibers in 1717. A globular myelin theory followed, claiming all elements of the nervous system except for Fontana's primitive cylinder with outer sheath in 1781. Remak's axon revolution in 1836 relegated
openaire   +3 more sources

Learning Myelin Content in Multiple Sclerosis from Multimodal MRI through Adversarial Training [PDF]

open access: yes, 2018
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). A reliable measure of the tissue myelin content is therefore essential for the understanding of the physiopathology of MS, tracking progression and assessing treatment efficacy.
arxiv   +1 more source

MiR-219a-5p Enriched Extracellular Vesicles Induce OPC Differentiation and EAE Improvement More Efficiently Than Liposomes and Polymeric Nanoparticles

open access: yesPharmaceutics, 2020
Remyelination is a key aspect in multiple sclerosis pathology and a special effort is being made to promote it. However, there is still no available treatment to regenerate myelin and several strategies are being scrutinized.
Iñaki Osorio-Querejeta   +17 more
doaj   +1 more source

A multi-spectral myelin annotation tool for machine learning based myelin quantification [version 4; peer review: 2 approved]

open access: yesF1000Research, 2023
Myelin is an essential component of the nervous system and myelin damage causes demyelination diseases. Myelin is a sheet of oligodendrocyte membrane wrapped around the neuronal axon.
Abdulkerim Çapar   +6 more
doaj  

Confined Multilamellae Prefer Cylindrical Morphology [PDF]

open access: yesarXiv, 2005
By evaporating a drop of lipid dispersion we generate the myelin morphology often seen in dissolving surfactant powders. We explain these puzzling nonequilibrium structures using a geometric argument: The bilayer repeat spacing increases and thus the repulsion between bilayers decreases when a multilamellar disk is converted into a myelin without gain ...
arxiv  

Myelin and saltatory conduction [PDF]

open access: yesarXiv, 2017
Essential tutorial on myelin, oligodendrocytes and their functional relevance in the pathophysiology of the brain.
arxiv  

Effects of Synaptic and Myelin Plasticity on Learning in a Network of Kuramoto Phase Oscillators [PDF]

open access: yes, 2019
Models of learning typically focus on synaptic plasticity. However, learning is the result of both synaptic and myelin plasticity. Specifically, synaptic changes often co-occur and interact with myelin changes, leading to complex dynamic interactions between these processes.
arxiv   +1 more source

Reflective imaging of myelin integrity in the human and mouse central nervous systems

open access: yesFrontiers in Cellular Neuroscience
The structural integrity of myelin sheaths in the central nervous system (CNS) is crucial for the maintenance of its function. Electron microscopy (EM) is the gold standard for visualizing individual myelin sheaths.
Georgina A. Craig   +12 more
doaj   +1 more source

The microglial "activation" continuum: from innate to adaptive responses

open access: yesJournal of Neuroinflammation, 2005
Microglia are innate immune cells of myeloid origin that take up residence in the central nervous system (CNS) during embryogenesis. While classically regarded as macrophage-like cells, it is becoming increasingly clear that reactive microglia play more ...
Nikolic Veljko, Town Terrence, Tan Jun
doaj   +1 more source

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