CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation
Journal of Neuroinflammation, 2020 Background The presence of foamy macrophages and microglia containing intracellular myelin remnants is a pathological hallmark of neurodegenerative disorders such as multiple sclerosis (MS).
Elien Grajchen +11 more
semanticscholar +1 more source
Exogenous lipids in myelination and myelination.
The Kaohsiung journal of medical sciences, 1997 Myelinogenesis is a scheduled process that depends on both the intrinsic properties of the cell and extracellular signals. In rat brain, myelin development is an essentially postnatal event and environmental interferences could affect myelin synthesis. Nutrition plays an important role, since severe postnatal malnutrition and essential fatty acid (EFA)
Serafina Salvati, Di Biase A
openaire +3 more sources
Nanoscale correlated disorder in out-of-equilibrium myelin ultrastructure
, 2017 Ultrastructural fluctuations at nanoscale are fundamental to assess properties and functionalities of advanced out-of-equilibrium materials. We have taken myelin as a model of supramolecular assembly in out-of-equilibrium living matter.
Bianconi, Antonio +6 more
core +1 more source
AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks [PDF]
, 2017 Segmentation of axon and myelin from microscopy images of the nervous system provides useful quantitative information about the tissue microstructure, such as axon density and myelin thickness. This could be used for instance to document cell morphometry
Antonsanti, Pierre-Louis +5 more
core +3 more sources
Myelin figures: the buckling and flow of wet soap
, 2009 Myelin figures are interfacial structures formed when certain surfactants swell in excess water. Here, I present data and model calculations suggesting myelin formation and growth is due to the fluid flow of surfactant, driven by the hydration gradient ...
A. M. Figueiredo Neto +3 more
core +1 more source
Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]
, 2019 Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S. +7 more
core +2 more sources
Oligodendrocyte Development and Implication in Perinatal White Matter Injury
Frontiers in Cellular Neuroscience, 2021 Perinatal white matter injury (WMI) is the most common brain injury in premature infants and can lead to life-long neurological deficits such as cerebral palsy. Preterm birth is typically accompanied by inflammation and hypoxic-ischemic events.
Mahsa Motavaf +4 more
doaj +1 more source
Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis. [PDF]
, 2019 Mesenchymal stem/stromal cells (MSCs) display potent immunomodulatory and regenerative capabilities through the secretion of bioactive factors, such as proteins, cytokines, chemokines as well as the release of extracellular vesicles (EVs).
Barthe, Sylvain +11 more
core +2 more sources
On the stability and growth of single myelin figures
, 2005 Myelin figures are long thin cylindrical structures that typically grow as a dense tangle when water is added to the concentrated lamellar phase of certain surfactants.
A. Filippov +6 more
core +1 more source
Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination [PDF]
, 2017 Remyelination is in the center of new therapies for the treatment of multiple sclerosis to resolve and improve disease symptoms and protect axons from further damage.
Bramlett +38 more
core +1 more source