Results 121 to 130 of about 85,576 (287)

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]

, 2008
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama, Bruce C. Richardson, Dipak Patel, Faith M. Strickland, Sushma Yarlagadda   +4 more
core   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Myelin basic protein in the cerebrospinal fluid of patients infected with HIV [PDF]

, 1989
Ackenheil, M., Bogner, Johannes R., Einhäupl, Karl Max, Fateh-Moghadam, A., Fröschl, M., Goebel, Frank-Detlef, Heinrich, B., Huber, M., Matuschke, A., Pfister, Hans-Walter, Pfäffl, M., Schielke, E., Wick, M.   +12 more
core   +1 more source

Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-β and AβPP in Adult Rat Brain. [PDF]

, 2015
BackgroundIschemia, white matter injury, and Alzheimer's disease (AD) pathologies often co-exist in aging brain. How one condition predisposes to, interacts with, or perhaps causes the others remains unclear.ObjectivesTo better understand the link ...
Ander, Bradley P, Cox, Christopher, Jickling, Glen C, Jin, Lee-Way, Liu, Dazhi, Sharp, Frank R, Stamova, Boryana, Zhan, Xinhua   +7 more
core  

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

iLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang, Xueying Zhang, Wen Deng, Fangning Gao, Shujia Peng, Guoqiang Bao, Lijuan Yuan   +6 more
wiley   +1 more source

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca, Gianmauro Palombelli, Nicola Vanacore, Rossella Canese   +3 more
wiley   +1 more source

Effect of High Intensity Exercise Preconditioning on the Prevention of Myelin damage in Hippocampus of Male C57BL/6 Mice

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2019
Introduction: Multiple sclerosis (MS) is a common neurodegenerative disease leading to the movement disorder and destruction of myelin. Physical exercise delays the onset of neurodegenerative processes by preventing the destruction of myelin and ...
Maryam Naghibzadeh, Rohullah Ranjbar, Mohammad Reza Tabandeh, Abdolhamid Habibi   +3 more
doaj   +2 more sources

FLAMES with Elevated Myelin Basic Protein Followed by Myelitis. [PDF]

Intern Med, 2022
Hokama H, Sakamoto Y, Hayashi T, Hatake S, Takahashi M, Kodera H, Kutsuna A, Nito C, Nakane S, Nagayama H, Takahashi T, Kimura K.   +11 more
europepmc   +1 more source

Probiotic consumption reduces alveolar bone loss and kidney damage in pregnant rats with experimental periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) is a probiotic bacterial strain with immunomodulatory properties. Its benefits have been observed in healthy and systemically compromised animals with periodontitis (PD). Our objective was to investigate the local and systemic effects of the systemic administration of B.
Átila V. V. Nobre, Pedro H. F. Silva, Marina C. G. Del‐Arco, Raquel F. Gerlach, Rene S. Oliezer, José E. Tanus‐Santos, Luciene C. Figueiredo, Janaina S. A. M. Evangelista, Flávia A. C. Furlaneto, Michel R. Messora, Sérgio Luiz Salvador   +10 more
wiley   +1 more source