Results 61 to 70 of about 107,221 (257)

Myelin basic protein charge isomers change macrophage polarization

open access: yesJournal of Inflammation Research, 2019
Elene Tsitsilashvili,1 Maia Sepashvili,1,2 Marika Chikviladze,1 Lali Shanshiashvili,1,2,* David Mikeladze1,2,* 1Institute of Chemical Biology, Ilia State University, Tbilisi, Georgia; 2Department of Biochemistry, I.
Tsitsilashvili E   +4 more
doaj  

Axon myelin transfer of a non-enveloped virus. [PDF]

open access: yesPLoS ONE, 2007
We showed previously that Theiler's virus, a neurotropic non-enveloped picornavirus of mouse, traffics from the axon of infected neurons into the surrounding myelin. When this traffic is interrupted, as in the shiverer mouse which bears a mutation in the
Jean-Pierre Roussarie   +4 more
doaj   +1 more source

Three dimensional chaos game representation of protein sequences [PDF]

open access: yesarXiv, 2023
A new three dimensional approach to the chaos game representation of protein sequences is explored in this thesis. The basics of DNA, the synthesis of proteins from DNA, protein structure and functionality and sequence alignment techniques are presented.
arxiv  

The self-referring DNA and protein: a remark on physical and geometrical aspects [PDF]

open access: yesPhilos Trans A 2016 Mar 13; 374(2063). pii: 20150070, 2018
All known life forms are based upon a hierarchy of interwoven feedback loops, operating over a cascade of space, time and energy scales. Among the most basic loops are those connecting DNA and proteins. For example, in genetic networks, DNA genes are expressed as proteins, which may bind near the same genes and thereby control their own expression.
arxiv   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

open access: yesAdvanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han   +10 more
wiley   +1 more source

The peritumoral brain zone in glioblastoma: where we are and where we are going

open access: yesJournal of Neuroscience Research, Volume 101, Issue 2, Page 199-216, February 2023., 2023
Abstract Glioblastoma (GBM) is the most aggressive and invasive primary brain tumor. Current therapies are not curative, and patients' outcomes remain poor with an overall survival of 20.9 months after surgery. The typical growing pattern of GBM develops by infiltrating the surrounding apparent normal brain tissue within which the recurrence is ...
Martina Giambra   +8 more
wiley   +1 more source

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

open access: yesAdvanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang   +10 more
wiley   +1 more source

Wireless Communication in Biosystems [PDF]

open access: yesarXiv, 2017
Electrical signals play the primary role in rapid communication among organs, tissues and cells in biosystems. We have analyzed and discussed three phenomena of electrical communication in biosystems, including direction-changing movement of paramecia, prey behavior of flytraps, and simultaneous discharge of electric ells.
arxiv  

Construction of a Biomimetic Tubular Scaffold Inspired by Sea Sponge Structure: Sponge‐Like Framework and Cell Guidance

open access: yesAdvanced Science, EarlyView.
Inspired by the structure of sea sponges, a unique method involving microfluidic coaxial spinning and in situ polymerization is designed. Biomimetic tubular scaffolds ae fabricated. Composed of specific materials such as oxidized bacterial cellulose, bacterial cellulose and polydopamine, these scaffolds have excellent mechanical stability and ...
Si Meng   +10 more
wiley   +1 more source

The Multiple Roles of Myelin Protein Genes During the Development of the Oligodendrocyte

open access: yesASN Neuro, 2009
It has become clear that the products of several of the earliest identified myelin protein genes perform functions that extend beyond the myelin sheath. Interestingly, these myelin proteins, which comprise proteolipid protein, 2′, 3′-cyclic nucleotide 3′-
Daniel Fulton   +2 more
doaj   +1 more source

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