Results 61 to 70 of about 212,048 (261)

Heterogeneous Nuclear Ribonucleoprotein (hnRNP) F Is a Novel Component of Oligodendroglial RNA Transport Granules Contributing to Regulation of Myelin Basic Protein (MBP) Synthesis*

open access: yesJournal of Biological Chemistry, 2011
Background: Myelin basic protein (MBP) synthesis and Fyn kinase activity are important for CNS myelination. Results: Oligodendroglial hnRNP F is associated with RNA granules, a target of Fyn, and modulates MBP translation.
Robin White   +5 more
semanticscholar   +1 more source

Preliminary Evidence of Increased Hippocampal Myelin Content in Veterans with Posttraumatic Stress Disorder. [PDF]

open access: yes, 2015
Recent findings suggest the formation of myelin in the central nervous system by oligodendrocytes is a continuous process that can be modified with experience.
Chao, Linda L   +4 more
core   +1 more source

Structural and molecular characteristics of axons in the long head of the biceps tendon [PDF]

open access: yes, 2020
The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain.
Blumer, Roland   +7 more
core   +1 more source

Characterization of mouse myelin basic protein messenger RNAs with a myelin basic protein cDNA clone. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1984
Using a family of synthetic tetradecamer oligonucleotides as a primer for cDNA synthesis and a second family of tetradecamers as a hybridization probe, we have prepared and isolated a cDNA clone of mouse myelin basic protein (MBP). The clone, pNZ111, corresponds to the region of the mRNA that codes for an amino acid sequence present in all four major ...
Anthony T. Campagnoni   +4 more
openaire   +3 more sources

Effect of Sox10 on remyelination of the hippocampus in cuprizone‐induced demyelinated mice

open access: yesBrain and Behavior, 2020
Objective The low number of oligodendrocytes (OLs) in the hippocampus of patients with schizophrenia suggests that hippocampal demyelination is changed in this condition. Sox10 is expressed throughout OL development.
Yu Shao   +7 more
doaj   +1 more source

Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-β and AβPP in Adult Rat Brain. [PDF]

open access: yes, 2015
BackgroundIschemia, white matter injury, and Alzheimer's disease (AD) pathologies often co-exist in aging brain. How one condition predisposes to, interacts with, or perhaps causes the others remains unclear.ObjectivesTo better understand the link ...
Ander, Bradley P   +7 more
core  

Nanoscale correlated disorder in out-of-equilibrium myelin ultrastructure

open access: yes, 2017
Ultrastructural fluctuations at nanoscale are fundamental to assess properties and functionalities of advanced out-of-equilibrium materials. We have taken myelin as a model of supramolecular assembly in out-of-equilibrium living matter.
Bianconi, Antonio   +6 more
core   +1 more source

The lateral membrane organization and dynamics of myelin proteins PLP and MBP are dictated by distinct galactolipids and the extracellular matrix. [PDF]

open access: yesPLoS ONE, 2014
In the central nervous system, lipid-protein interactions are pivotal for myelin maintenance, as these interactions regulate protein transport to the myelin membrane as well as the molecular organization within the sheath. To improve our understanding of
Hande Ozgen   +7 more
doaj   +1 more source

Tau Isoform-Driven CBD Pathology Transmission in Oligodendrocytes in Humanized Tau Mice

open access: yesFrontiers in Neurology, 2021
The aggregation of abnormally phosphorylated tau protein in neurons and glia is a neuropathological hallmark of several neurodegenerative disorders, collectively known as tauopathies.
Justyna Zareba-Paslawska   +4 more
doaj   +1 more source

Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination [PDF]

open access: yes, 2017
Remyelination is in the center of new therapies for the treatment of multiple sclerosis to resolve and improve disease symptoms and protect axons from further damage.
Bramlett   +38 more
core   +1 more source

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