Effect of Sox10 on remyelination of the hippocampus in cuprizone‐induced demyelinated mice
Objective The low number of oligodendrocytes (OLs) in the hippocampus of patients with schizophrenia suggests that hippocampal demyelination is changed in this condition. Sox10 is expressed throughout OL development.
Yu Shao +7 more
doaj +1 more source
Infectious diseases and autoimmunity [PDF]
Introduction: Autoimmunity occurs when the immune system recognizes and attacks host tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria and other infectious pathogens) are thought to play a major role in the ...
Deidda, Silvia +3 more
core +1 more source
We have developed a smart hair‐repair ingredient based on β‐carboxylic acid amide that undergoes negative‐to‐positive charge conversion under mildly acidic conditions. The initial negative charge facilitates deep penetration into the hair fiber, while the subsequent positive charge enables re‐bonding with sulfonate groups in damaged hair keratin.
Sunyoung Kang +8 more
wiley +1 more source
Evidence that an RGD-dependent receptor mediates the binding of oligodendrocytes to a novel ligand in a glial-derived matrix. [PDF]
A simple adhesion assay was used to measure the interaction between rat oligodendrocytes and various substrata, including a matrix secreted by glial cells. Oligodendrocytes bound to surfaces coated with fibronectin, vitronectin and a protein component of
Cardwell, MC, Rome, LH
core
MicroRNA-23a promotes myelination in the central nervous system. [PDF]
Demyelinating disorders including leukodystrophies are devastating conditions that are still in need of better understanding, and both oligodendrocyte differentiation and myelin synthesis pathways are potential avenues for developing treatment ...
Fu, Ying-Hui +5 more
core +2 more sources
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton +2 more
wiley +1 more source
The Multiple Roles of Myelin Protein Genes During the Development of the Oligodendrocyte
It has become clear that the products of several of the earliest identified myelin protein genes perform functions that extend beyond the myelin sheath. Interestingly, these myelin proteins, which comprise proteolipid protein, 2′, 3′-cyclic nucleotide 3′-
Daniel Fulton +2 more
doaj +1 more source
The lateral membrane organization and dynamics of myelin proteins PLP and MBP are dictated by distinct galactolipids and the extracellular matrix. [PDF]
In the central nervous system, lipid-protein interactions are pivotal for myelin maintenance, as these interactions regulate protein transport to the myelin membrane as well as the molecular organization within the sheath. To improve our understanding of
Hande Ozgen +7 more
doaj +1 more source
The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]
We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Jessen, KR +6 more
core

