Results 171 to 180 of about 119,819 (305)

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Human Peripheral Myelin Protein 2 and Charcot-Marie-Tooth Disease or Structural Missense Variants Show Different Binding to Myelin-Like Lipid Monolayers. [PDF]

Chembiochem
Schöffmann FA, Imran MAS, Schwieger C, Hetland Ø, Jerschabek V, Raasakka A, Kursula P, Hinderberger D.   +7 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Dysregulated lipid metabolism and hypomyelination in postnatal peroxisome-deficient <i>Pex2</i> knockout Zellweger mice. [PDF]

Front Mol Neurosci
Eberhart T, Charles KN, Salumbides-Torres B, Price N, Fliesler SJ, Faust PL, Kovacs WJ.   +6 more
europepmc   +1 more source

Force stimulation promotes nerve regeneration by restoring cellular energy

BMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang, Chen Cai, Hetao Xie, Yupeng Yang, Lei Li, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Meiwan Chen, Yuanhua Sang, Bing Ji, Zenan Wang   +10 more
wiley   +1 more source

Assessing Age-Associated Influences on Paramagnetic and Diamagnetic Susceptibility Maps in Postmortem Human Brains. [PDF]

NMR Biomed
de Azevedo JHM, Garcia Otaduy MC, Avanzine A, Diehl Rodriguez R, Seiji Otsuka F, Barbosa F, Liu C, Garrido Salmon CE.   +7 more
europepmc   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

Myelin-specific IL2 + T-cells are associated with last occurring relapse severity in relapsing-remitting multiple sclerosis. [PDF]

Sci Rep
Zilkha-Falb R, Drori T, Shwartz K, Gurevich M.   +3 more
europepmc   +1 more source

Development and Retrospective Application of Novel Outcome Measure: Sturge–Weber Syndrome Acute Crisis (SWAC) Index

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Sturge–Weber syndrome (SWS) symptoms frequently overlap in neurological acute crises (ACs) presenting with seizures, stroke‐like episodes (SLE), and headaches. Recent efforts to develop a prospective drug trial highlighted the need for a new outcome measure capable of quantifying these symptoms during an SWS AC.
Kieran D. McKenney, Luther G. Kalb, Adrienne M. Hammill, Anne M. Comi   +3 more
wiley   +1 more source

Why Is MS a More Frequent Complication of EBV Infection in Females? [PDF]

Immunol Rev
Dunn SE, Alvarez-Sanchez N, Steinman L.
europepmc   +1 more source