Results 181 to 190 of about 1,649,424 (250)

Temporal Mapping of CSVD-Related White Matter Lesions and Concurrent Neurovascular Dysfunction in Spontaneously Hypertensive Rats. [PDF]

CNS Neurosci Ther
Peng J, Ni J, Li F, Li T, Wei M, Ge T, Yao L, Shi J, Tian J.   +8 more
europepmc   +1 more source

Altered Translational Control of Fragile X Mental Retardation Protein on Myelin Proteins in Neuropsychiatric Disorders. [PDF]

Biomol Ther (Seoul), 2017
Jeon SJ, Ryu JH, Bahn GH.
europepmc   +1 more source

SpaceNet: Pathology‐guided analysis of lesion‐associated spatial molecular programs

iMetaOmics, EarlyView.
Disease‐associated molecular alterations are often confined to localized pathological regions, yet current spatial transcriptomic analyses do not always use pathology or imaging information as the primary reference for defining disease‐relevant spatial contexts.
Menglei Wang, Qikun Zhao, Hudong Bao, Kaiyu Jin, Xiaohui Fan, Jie Liao   +5 more
wiley   +1 more source

Subacute Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine Exposure Induces Neurobehavioral Deficits and Hippocampal Demyelination in Mice. [PDF]

Toxics
Lv X, Li C, Zhang Y, Luo Q, Gao T, Deng H, Li H, Peng X, Shen J, Liu S, Gao J, Liu Z.   +11 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Mitochondrial Control of Myelination, Bioenergetics, Oxidative Stress, and the Pathogenesis of Optic Neuropathies. [PDF]

Int J Mol Sci
Sahibzada H, Malik R, Abu-Amero KK.
europepmc   +1 more source

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Cdk7 Regulates Myelin Sheath Morphology and Lipid Homeostasis in Schwann Cells. [PDF]

Glia
Schumacher N, Pieltain A, Tocquin P, Thelen N, Lavergne A, Masar N, Terrasi R, Leloup R, Muccioli G, Gailly P, Arthur-Farraj P, Vandenbosch R, Franzen R.   +12 more
europepmc   +1 more source

Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment

iNew Medicine, EarlyView.
ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su, Fei Wang, Ting‐Hong Wei, Rui Lu, Wen‐Jun Huang, Xiang Zhang, Ling Yin, Jun Li   +7 more
wiley   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea. [PDF]

Glia
Williamson MR, Botas J, Hedayatpour MJ, Zlatkov T, Harmanci AS, Yates CJ, Nobleza K, Ailani R, Adler AC, Kheradmand F, Lee HK, Deneen B, Jeong HH, Chandrakantan A.   +13 more
europepmc   +1 more source