Results 181 to 190 of about 119,819 (305)

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Multiple sclerosis and autoimmunity: a reappraisal of the evidence. [PDF]

Front Immunol
Amigo M, Sen MK, Dunn JS, Mahns DA.
europepmc   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Clemastine Restores Myelination Protein Expression in S16 Schwann Cells by Enhancing AMPK Activation and Reducing H₂O₂-Induced Oxidative Stress. [PDF]

Biomol Ther (Seoul)
Yun C, Lee SY, Won JH, Kim GH, Kim TH, Lee JI.   +5 more
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Reduced Oligodendrocyte Density and Axonal Caliber Associated With Mitochondrial Alterations in the White Matter of Chronically‐Starved Mice

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with extreme weight loss, hyperactivity, and amenorrhea. Neuroimaging studies revealed brain atrophy and disruption of white matter integrity in the corpus callosum (CC) of patients with AN. However, the underlying pathophysiological mechanisms remain unclear.
Stephan Lang, Annelie Zimmermann, Kaja Dickert, Hanna Rupprecht, Julia Priebe, Fabienne Haberland, Hanna‐Sophia Henschke, Katharina Schuster, Marcus Frank, Linda Frintrop   +9 more
wiley   +1 more source

Paradoxes in the Ontological Classification of Glia-Evidence for an Important New Class of Brain Cells with Primary Functions in Iron Regulation. [PDF]

Cells
Milward AE, Hood RJ, Lin CA, Bettencourt C, Acquah E, Brooks J, Collingwood JF, Kagawa Y, Richardson SJ, Wu Y, Lu Y, Dottori M, Johnstone DM.   +12 more
europepmc   +1 more source

Differential regulation of nerve growth factor and brain-derived neurotrophic factor expression in the peripheral nervous system [PDF]

, 1991
HANS THOENEN, Hofer M., ICHIRO MATSUOKA, Lindholm D., Lindholm D., M. HOFER, MICHAEL MEYER   +6 more
core   +1 more source

Fish Scales: A Multifunctional Biomaterial from Nature

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley   +1 more source

Proteomic Characterization of Spinal Cord Myelin in the Mouse. [PDF]

ASN Neuro
Schmitt O, Kaddatz H, Mikkat S, Kipp M, Schümann A, Joost S.   +5 more
europepmc   +1 more source