Results 181 to 190 of about 5,787,020 (354)

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Immunodominant fragments of myelin basic protein initiate T cell-dependent pain [PDF]

, 2012
Huaqing Liu, Sergey A. Shiryaev, Andrei V. Chernov, Youngsoon Kim, Igor Shubayev, Albert G. Remacle, Svetlana Baranovskaya, Vladislav S. Golubkov, Alex Y. Strongin, Veronica I. Shubayev   +9 more
openalex   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

Advanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang, Tao Zhang, Yuan Chen, Nikolaos Kourkoumelis, Mo Chen, Jiale Dong, Zhenyu Li, Yanling Zhou, Ning Li, Chen Zhu, Xifu Shang, Jiaxiang Bai, Xianzuo Zhang   +12 more
wiley   +1 more source

On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation. [PDF]

FEBS J
Krokengen OC, Raasakka A, Klenow MB, Pal A, Hetland Ø, Mularski A, Ruskamo S, Pedersen JS, Simonsen AC, Kursula P.   +9 more
europepmc   +1 more source

Short-lived complexes between myelin basic protein peptides and IAk.

, 1994
Karen Mason, Harden M. McConnell
openalex   +2 more sources

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Turnover of myelin proteins in mouse brain in vivo.

Biochemical Journal, 1977
A. Lajtha, J. Toth, K. Fujimoto, H. Agrawal   +3 more
semanticscholar   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Tumor necrosis factor receptor 2 activation elicits sex-specific effects on cortical myelin proteins and functional recovery in a model of multiple sclerosis. [PDF]

Brain Res Bull
Nguyen KL, Bhatt IJ, Gupta S, Showkat N, Swanson KA, Fischer R, Kontermann RE, Pfizenmaier K, Bracchi-Ricard V, Bethea JR.   +9 more
europepmc   +1 more source

Deletion of Jun Proteins in Adult Oligodendrocytes Does Not Perturb Cell Survival, or Myelin Maintenance In Vivo

, 2015
Bettina Schreiner, Barbara Ingold‐Heppner, Debora Pehl, Giuseppe Locatelli, Helia Berrit-Schönthaler, Burkhard Becher   +5 more
openalex   +2 more sources