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Evolution of myelin ultrastructure and the major structural myelin proteins
Brain Research, 2016Myelin sheaths, as the specialized tissue wrapping the nerve fibers in the central and peripheral nervous systems (CNS and PNS), are responsible for rapid conduction of electrical signals in these fibers. We compare the nerve myelin sheaths of different phylogenetic origins-including mammal, rodent, bird, reptile, amphibian, lungfish, teleost, and ...
Hideyo, Inouye, Daniel A, Kirschner
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The distribution of myelin basic protein mRNAs within myelinating oligodendrocytes
Trends in Neurosciences, 1993The nervous system contains oligodendrocytes with processes that are greatly extended in space. It is now clear that there are numerous complex, poorly understood mechanisms by which polypeptides are synthesized and delivered to their sites of function in these cells.
P J, Brophy, G L, Boccaccio, D R, Colman
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Myelin basic protein: a multifunctional protein
Cellular and Molecular Life Sciences, 2006Myelin basic protein (MBP), the second most abundant protein in central nervous system myelin, is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin. A member of the 'intrinsically disordered' or conformationally adaptable protein family, it also appears to have several other functions.
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From Myelin Basic Protein to Myelin Deficient Mice
1990In order to control diseases affecting myelination, an understanding of normal myelin structure and its formation is essential. Paradoxically, much information about normal development can be obtained through investigations of hypomyelinated mutants.
M. Tosic, J.-M. Matthieu
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The phosphorylation of myelin proteins
Progress in Neurobiology, 1988Abbreviations I. Overview 2. General introduction 2.1. Myelin 2.2. Myelination 2.3. Myelin basic protein 2.4. Protein phosphorylation 3. Protein kinases that act on myelin basic protein 3.1. Cyclic AMP-dependent kinase 3.2. Calcium-dependent kinases 3.3. Other kinases 4. Phosphoprotein phosphatases that act on myelin basic protein 5. Phosphorylation of
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1995
Myelin basic protein is a structural protein of the nervous system composed of three structural units joined by double phenylalanine residues. The central unit of this stucture — the B fragment — can be found free within the CSF in cases of demyelination or cerebral damage.
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Myelin basic protein is a structural protein of the nervous system composed of three structural units joined by double phenylalanine residues. The central unit of this stucture — the B fragment — can be found free within the CSF in cases of demyelination or cerebral damage.
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Myelin Enzymes and Protein Metabolism
1972Turnover of myelin has attracted interest in relation to clinical and experimental diseases involving demyelination (7, 11). In adult rats, myelin represents about 12 % of total fresh weight, of which some 25 % is protein (14) and earlier concepts for its relative inertness are difficult to reconcile with the known halflife of under 20 days for 90 % of
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly

