Results 281 to 290 of about 130,050 (381)

Claudin-11, a hypomyelinating leukodystrophy 22 (HLD22)-responsible protein, uniquely interacts with shroom-2 to change cell phenotypes. [PDF]

BBA Adv
Kobayashi S, Yokoi T, Omata T, Yako H, Miyamoto Y, Yamauchi J.   +5 more
europepmc   +1 more source

Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform

Movement Disorders, EarlyView.
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles, Dilan Athauda, Thomas R. Barber, Roger A. Barker, David T. Dexter, Susan Duty, Romy Ellis‐Doyle, Sonia Gandhi, Joel Handley, Edwin Jabbari, Keith Martin, Kevin McFarthing, Georgia Mills, Heather Mortiboys, Stephen Mullin, Rebecca Petty, Esther Sammler, Paula Scurfield, Simon R.W. Stott, George K. Tofaris, Li Wei, Caroline H. Williams‐Gray, Alan Wong, Marie‐Louise Zeissler, Richard K. Wyse, Camille B. Carroll, Thomas Foltynie, Oliver Bandmann, Anthony H.V. Schapira, on behalf of the EJS ACT‐PD Consortium   +29 more
wiley   +1 more source

Combined transcriptomic and proteomic analyses reveal relevant myelin features in mice with ischemic stroke. [PDF]

Funct Integr Genomics
Qian Q, Lyu H, Wang W, Wang Q, Li D, Liu X, He Y, Shen M.   +7 more
europepmc   +1 more source

Corticospinal Tract Development, Evolution, and Skilled Movements

Movement Disorders, EarlyView.
Abstract The evolution of the corticospinal tract (CST) is closely linked to the development of skilled voluntary movements in mammals. The main evolutionary divergence concerns the position of the CST within the spinal cord white matter and its postsynaptic targets in the grey matter.
Emmanuel Roze, Caroline Dubacq, Quentin Welniarz   +2 more
wiley   +1 more source

Characteristics of in vitro cytotoxic effects of myelin basic protein-reactive T cell lines on syngeneic oligodendrocytes

, 1990
Kuniyuki Kawai, Burton Zweiman
openalex   +1 more source

Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik, YuHong Fu, Russell Pickford, Qi Cheng, Yue Yang, Simon J.G. Lewis, Nicolas Dzamko, Glenda M. Halliday, Woojin Scott Kim   +8 more
wiley   +1 more source

Mitochondria transfer for myelin repair. [PDF]

J Cereb Blood Flow Metab
Mozafari S, Peruzzotti-Jametti L, Pluchino S.   +2 more
europepmc   +1 more source

Detection and processing of peripheral myelin protein PMP22 in cultured Schwann cells

, 1993
Sangeeta Pareek, Ueli Suter, G. Jackson Snipes, Andrew A. Welcher, E.M. Shooter, Richard A. Murphy   +5 more
openalex   +1 more source

Saturation transfer MR fingerprinting for magnetization transfer contrast and chemical exchange saturation transfer quantification

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose The aim of this study was to develop a saturation transfer MR fingerprinting (ST‐MRF) technique using a biophysics model‐driven deep learning approach. Methods A deep learning–based quantitative saturation transfer framework was proposed to estimate water, magnetization transfer contrast, and amide proton transfer (APT) parameters plus
Munendra Singh, Beomgu Kang, Sultan Z. Mahmud, Peter van Zijl, Jinyuan Zhou, Hye‐Young Heo   +5 more
wiley   +1 more source

Novel Cell Models to Study Myelin and Microglia Interactions. [PDF]

Int J Mol Sci
Santacreu-Vilaseca M, Moreno-Magallon J, Juanes-Casado A, Gil-Sánchez A, González-Mingot C, Torres P, Brieva L.   +6 more
europepmc   +1 more source