Results 281 to 290 of about 5,666,125 (336)
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From the syndrome of Charcot, Marie and Tooth to disorders of peripheral myelin proteins.
Brain : a journal of neurology, 1995The description of the peroneal muscular atrophy syndrome in 1886 by Charcot, Marie and Tooth was followed by an era of nosological confusion. This was partly clarified by the advent of nerve conduction studies and the definition of the most common, but ...
A. Harding
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Native myelin proteins and myelin assembly in the central nervous system
1991Myelin is a membrane required for impulse conduction in the nervous system. In line with its unique function, myelin possesses properties which cannot be compared with other biological structures (Raine, 1984).
Riccio P +4 more
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Proteins and enzymes of myelin [PDF]
, 1977 Current views on the structure of membranes assume that the genetic control over their structure and assembly is asserted via the protein components and that the nature and alignment of lipids depends on the amino acid sequence of the proteins. Demyelination may result from a defective myelin protein or damage to part of the protein framework which ...
P. R. Carnegie, N. R. Sims
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Autoimmunity to Myelin Basic Protein
1982Experimental allergic encephalomyelitis (EAE) is an autoimmune central nervous system (CNS) disease which has been studied extensively, and has provided insight into mechanisms of immune tissue damage and immunologic self-tolerance. In addition, EAE serves as a prototype for human demyelinating diseases such as multiple sclerosis1.
Joyce A. Killen +2 more
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Quantitation of myelination and demyelination by the measurement of myelin basic protein by ELISA
Journal of the Neurological Sciences, 1986Utilizing a competitive inhibition enzyme-linked immunosorbent assay (ELISA) we measured the amount of myelin basic protein (MBP) in brain, liver, and kidney of newborn mouse and compared these values with myelinated cerebellar explant cultures under various conditions.
J. Wang +4 more
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Myelin breakdown and basic protein
Experimental Neurology, 1974Abstract The purpose of the present work was to study the mechanisms of myelin breakdown in experimental conditions and the fate of protein components in myelin, especially that of myelin basic protein which is known to be important in demyelinative disorders. The results showed that when myelin was incubated alone without any added enzymes there was
Matias Röyttä +4 more
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1981
Myelin basic protein (MBP) has engaged the attention of molecular and cellular immunologists during the past decade because of its implication in the induction of the autoimmune disease experimental allergic encephalomyelitis (EAE) of the central nervous system (CNS).
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Myelin basic protein (MBP) has engaged the attention of molecular and cellular immunologists during the past decade because of its implication in the induction of the autoimmune disease experimental allergic encephalomyelitis (EAE) of the central nervous system (CNS).
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Crystallization of P2 myelin protein
Journal of Molecular Biology, 1987Single crystals of bovine P2 myelin protein have been grown in polyethylene glycol 4000 by the hanging-drop vapor diffusion method. Crystals belonging to space group P2(1)2(1)2(1) with cell dimensions a = 91.8 A, b = 99.5 A, c = 56.5 A (1 A = 0.1 nm). The diffraction pattern extends to better than 2.3 A resolution.
Torsten Unge +5 more
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Current Medicinal Chemistry, 2005
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and loss of neurological function, local macrophage infiltrate and neuroantigen-specific CD4(+)T cells.
A. Tzakos +7 more
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Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and loss of neurological function, local macrophage infiltrate and neuroantigen-specific CD4(+)T cells.
A. Tzakos +7 more
semanticscholar +1 more source
Turnover of proteins in myelin and myelin-like material of mouse brain
Brain Research, 1974Abstract Mice 14 or 60 days of age were injected intraperitoneally with [3H]leucine and were decapitated 10, 20, 40, and 80 days later. A crude fraction of brain myelin was isolated on a discontinuous sucrose gradient. Myelin was separated from the associated myelin-like material by osmotic shock and the two fractions were purified by differential ...
Carolyn A. Fischer +3 more
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