Results 91 to 100 of about 331,716 (264)

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

LIGHT AND TRANSMISSION ELECTRON MICROSCOPICAL OBSERVATIONS ON RAT SCIATIC NERVE INDUCED BY ELECTROCUTION [PDF]

Assiut Veterinary Medical Journal, 2014
The main objective of the present study was to investigate possible alterations of the sciatic nerve of rats exposed to 220 V for 30 seconds by light and transmission electron microscope (TEM).
DOAA SAFWAT, ADEL SHEHATA ISMAIL, MAHMUD ABD EL-NASER, OMAR H. BAYUOMI, SALAH AFIFI   +4 more
doaj   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Role of Dexras1-mediated inflammatory response in white matter damage after subarachnoid hemorrhage in rats

Di-san junyi daxue xuebao, 2020
Objective To explore the mechanisms by which Dexras1 promotes inflammation and participates in white matter damage (WMD) after subarachnoid hemorrhage (SAH). Methods Ninety healthy adult male SD rats were randomly divided into control group (sham group),
XIN Yuanjun, HUANG Hao, LIANG Yidan, QIN Wang, WU Xintong, LUO Xuefeng, LIANG Fuming, HE Zhaohui   +7 more
doaj   +1 more source

Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system

Developmental Cell, 2015
Summary During central nervous system development, oligodendrocytes wrap their plasma membrane around axons to generate multi-lamellar myelin sheaths.
S. Nawaz, Paula Sánchez, S. Schmitt, Nicolas Snaidero, M. Mitkovski, Caroline Velte, B. Brückner, Ioannis Alexopoulos, Tim Czopka, Sang Y. Jung, J. Rhee, A. Janshoff, W. Witke, I. Schaap, D. Lyons, M. Simons   +15 more
semanticscholar   +1 more source

Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism

Cells, 2020
Myelin is critical for the proper function of the nervous system and one of the most complex cell–cell interactions of the body. Myelination allows for the rapid conduction of action potentials along axonal fibers and provides physical and trophic ...
Y. Poitelon, Ashley M. Kopec, Sophie Belin   +2 more
semanticscholar   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Optical polarization evolution and transmission in multi-Ranvier-node axonal myelin-sheath waveguides

, 2023
In neuroscience, it is of interest to consider all possible modes of information transfer between neurons in order to fully understand processing in the brain.
Christoph Simon (3741511), Hadi Zadeh-Haghighi (12733853), Emily Frede (15187282)   +2 more
core   +2 more sources

The pathology of neuropathies with focal thickening of the myelin sheath (tomaculous neuropathy): Studies on the formation of the abnormal myelin sheath

, 1975
The sural nerves of 4 patients showed similar pathological features of sausage-shaped thickenings of the myelin sheaths ranging in length from 80 to 250 μm, of up to 27 μm diameter and affecting fibres of all sizes.
Madrid, R, Bradley, W.G
core   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source