Results 91 to 100 of about 53,780 (245)

Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo [PDF]

, 2013
The number of myelin sheaths made by individual oligodendrocytes regulates the extent of myelination, which profoundly affects central nervous system function.
Almeida, Brinkmann, Charles ffrench-Constant, Chong, Czopka, David A. Lyons, Dawson, Fields, Franklin, Franklin, Fünfschilling, Jopling, Kang, Kirby, Krämer-Albers, Kwan, Lamason, Laursen, Lee, Liu, Makinodan, Miller, Nave, Ng, Park, Provost, Remahl, Richardson, Savas, Sherman, Tim Czopka, Umemori, Wake, Watkins, White, Young, Zatorre, Zawadzka   +37 more
core   +2 more sources

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

TIMP-1 associates with myelin membrane and preserves myelin in injured peripheral nerve

Neurobiology of Disease
Myelin enables rapid impulse propagation in axons across long distances. Following peripheral nerve injury, Schwann cells provide trophic, metabolic, and immune support to damaged neurons.
Hanbum Joe, Hyungseok Seo, Jennifer Dolkas, Megh Jawala, Swathi K. Hullugundi, Yang Hoon Chung, Hemal H. Patel, Andrei V. Chernov, Veronica I. Shubayev   +8 more
doaj   +1 more source

Finite-Difference Time-Domain Simulation for Three-dimensional Polarized Light Imaging

, 2016
Three-dimensional Polarized Light Imaging (3D-PLI) is a promising technique to reconstruct the nerve fiber architecture of human post-mortem brains from birefringence measurements of histological brain sections with micrometer resolution.
A Taflove, AM Glazer, GF Göthlin, H Raedt De, KS Yee, M Axer, M Axer, M Dohmen, M Menzel, M Stephan, O Sporns, RC Jones, RC Jones, RS Bear, TEJ Behrens   +14 more
core   +1 more source

Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C. [PDF]

, 2013
VLGR1 (very large G protein-coupled receptor 1), also known as MASS1 (monogenic audiogenic seizure susceptible 1), is an orphan G protein-coupled receptor that contains a large extracellular N terminus with 35 calcium-binding domains.
Fu, Ying-Hui, Lin, Shu-Ting, Ptácek, Louis J, Shin, Daesung   +3 more
core   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]

, 2006
We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Jessen, KR, Meier, C, Mirsky, R, Sahni, V, Sharghi-Namini, S, Turmaine, M, Umehara, F   +6 more
core  

Galectin-1 in myelin repair [PDF]

, 2016
Galectin-1 (Gal-1) is a member of a highly conserved family of animal lectins which binds to the common disaccharide [Galβ(1-4)-GlcNAc] on both N- and O-glycans decorating cell surface glycoconjugates.
Pasquini, Laura Andrea, Rinaldi, Mariana, Thomas, Laura   +2 more
core   +2 more sources

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers. [PDF]

, 2016
PurposeWe present a case of bilateral extensive peripapillary myelinated retinal nerve fibers (MRNF) in an individual with Crouzon syndrome, an inherited form of craniosynostosis caused by overactivation of fibroblast growth factor receptor 2.
Akil, Handan, Apinyawasisuk, Supanut, Garcia, Giancarlo A, Kim, Sarah, Sadun, Alfredo A, Tian, Jack J   +5 more
core   +3 more sources