Results 121 to 130 of about 36,787 (207)
Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.This outlines the progress for developing a sleep‐modulating herbal formula (SMF). It begins with the identification of effective compounds and quality control, then uses network pharmacology and molecular docking to explain the mechanisms behind the observation found on the behavioural and neurobiological results in animal study.
Jasmine U. Ting +7 more
wiley +1 more source
Aging Cell, Volume 25, Issue 6, June 2026.Age, sex, and estrogen loss are widely recognized risk factors for Alzheimer's disease. Here, we show that brain‐specific aromatase knockout (bArKO) and the resulting estrogen loss lead to memory impairment, reduced social interaction, and extracellular environment dysregulation selectively in aged female mice, but not in young female or male mice ...
Natalie C. Piehl +12 more
wiley +1 more source
Proteomic Profiling of Cerebrum Mitochondria, Myelin Sheath, and Synaptosome Revealed Mitochondrial Damage and Synaptic Impairments in Association with 3 × Tg-AD Mice Model. [PDF]
Cell Mol Neurobiol, 2022 Shen L +11 more
europepmc +1 more source
Deferoxamine Improves Radiation‐Induced Peripheral Neuropathy
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Radiation‐induced peripheral neuropathy (RIPN) is a devastating sequela of radiation therapy (XRT). Current treatment options are limited. Deferoxamine (DFO) has been useful in treating radiation‐induced dermal fibrosis. This study aimed to evaluate DFO for RIPN. Thus, 18 mice received 30Gy of fractionated XRT.
Christopher V. Lavin +12 more
wiley +1 more source
A myelin sheath protein forming its lattice. [PDF]
J Biol Chem, 2020 Tsuge H.
europepmc +1 more source
Akt regulates axon wrapping and myelin sheath thickness in the PNS
The signaling pathways that regulate myelination in the PNS remain poorly understood. Phosphatidylinositol-4,5-bisphosphate 3-kinase 1A, activated in Schwann cells by neuregulin and the extracellular matrix, has an essential role in the early events of ...
Meng, Xiaosong +8 more
core +1 more source
Pain kept under wraps of myelin sheath. [PDF]
Front Pain Res (Lausanne)Shubayev VI.
europepmc +1 more source
Individual neuronal subtypes control initial myelin sheath growth and stabilization. [PDF]
Neural Dev, 2020 Nelson HN +9 more
europepmc +1 more source
Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan +2 more
wiley +1 more source