Results 141 to 150 of about 53,780 (245)
TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration
Advanced Science, Volume 13, Issue 25, 4 May 2026.TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu +9 more
wiley +1 more source
Axon and Myelin Sheath Segmentation in Electron Microscopy Images using Meta Learning. [PDF]
IEEE Appl Imag Pattern Recognit Workshop, 2022 Nguyen NP +5 more
europepmc +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
Effect of 17β estradiol on hippocampus region of aging female rat brain: Ultrastructural study
American Journal of Experimental and Clinical Research, 2015 Estradiol has direct membrane-mediated effects on neurons and its effects are both neuroprotective and neurotrophic. This hormone modulates brain development and aging and affects neurochemical systems which are affected in age-related cognitive decline,
Rashmi Jha +6 more
doaj
Advanced Science, Volume 13, Issue 25, 4 May 2026.A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu +6 more
wiley +1 more source
Brain and Behavior, Volume 16, Issue 5, May 2026.Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan +11 more
wiley +1 more source
Myelin sheath and cyanobacterial thylakoids as concentric multilamellar structures with similar bioenergetic properties. [PDF]
Open Biol, 2021 Morelli AM +4 more
europepmc +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT X‐linked adrenoleukodystrophy (X‐ALD) is a genetic peroxisome disorder linked to ABCD1 mutation, characterized by rapid and complex clinical symptoms. We here report a case of X‐ALD manifesting solely as dysarthria, associated with an undefined mutation in the ABCD1 gene, underscoring the necessity of atypical clinical symptoms in X‐ALD ...
Fu‐Qing Zhang +4 more
wiley +1 more source