Effects of normal aging on myelin sheath ultrastructures in the somatic sensorimotor system of rats
Fang Xie +4 more
openalex +3 more sources
White matter intercompartmental water exchange rates determined from detailed modeling of the myelin sheath. [PDF]
Purpose: Magnetization exchange (ME) between hydrogen protons of water and large molecules (semisolids [SS]) in lipid bilayers is an important factor in MRI signal generation and can be exploited to study white matter pathology.
van Gelderen P, Duyn JH.
europepmc +2 more sources
The effect of vascular graft and human umbilical cord blood-derived CD34+ stem cell on peripheral nerve healing [PDF]
AIM: There are many trials concerning peripheral nerve damage causes and treatment options. Unfortunately, nerve damage is still a major problem regarding health, social and economic issues.
Abban, G. +6 more
core +1 more source
Microtubules, Myelin Sheaths, and Altered Behavior [PDF]
Mice are skttish creatures that innately hide from perceived threats by staying out of open areas, freezing to avoid predators, or hiding in dark spaces when an adverse stimulus is sensed. However, after inducing a global TPPP (tubulin polymerization promoting protein) gene knock-out (KO), which results in reduced myelin length and thickness (Fu et al.,
openaire +2 more sources
Myelin sensitive MRI techniques, such as diffusion tensor imaging and myelin water imaging, have previously been used to reveal changes in myelin after sports-related concussions.
Alexander M. Weber +14 more
doaj +1 more source
C1q is essential for myelination in the central nervous system (CNS)
Summary: Myelin sheath in the central nervous system (CNS) is essential for efficient action potential conduction. Microglia, the macrophages in the CNS, are suggested to regulate myelin development.
Qiang Yu +6 more
doaj +1 more source
Myelin pathology: Involvement of molecular chaperones and the promise of chaperonotherapy [PDF]
The process of axon myelination involves various proteins including molecular chaperones. Myelin alteration is a common feature in neurological diseases due to structural and functional abnormalities of one or more myelin proteins.
Cappello F. +4 more
core +1 more source
Myelin-like sheaths in copepod axons [PDF]
Copepods, the small planktonic crustaceans that are the most abundant metazoans in the oceans, are so successful partly because they have an escape response that accelerates them to 200 body lengths per second within milliseconds1,3. We find that nerve fibres of many copepods seem to be designed for rapid signalling.
A D, Davis +3 more
openaire +2 more sources
Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination [PDF]
Remyelination is in the center of new therapies for the treatment of multiple sclerosis to resolve and improve disease symptoms and protect axons from further damage.
Bramlett +38 more
core +1 more source
Effect of Sox10 on remyelination of the hippocampus in cuprizone‐induced demyelinated mice
Objective The low number of oligodendrocytes (OLs) in the hippocampus of patients with schizophrenia suggests that hippocampal demyelination is changed in this condition. Sox10 is expressed throughout OL development.
Yu Shao +7 more
doaj +1 more source

