Simulation of nerve fiber based on anti-resonant reflecting optical waveguide
Scientific Reports, 2022 Light and optical techniques are widely used for the diagnosis and treatment of neurological diseases as advanced methods. Understanding the optical properties of nervous tissue and nerve cells is vital.
Marzieh Omidi +2 more
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Myelin Proteomics: Molecular Anatomy of an Insulating Sheath [PDF]
Molecular Neurobiology, 2009 Fast-transmitting vertebrate axons are electrically insulated with multiple layers of nonconductive plasma membrane of glial cell origin, termed myelin. The myelin membrane is dominated by lipids, and its protein composition has historically been viewed to be of very low complexity.
Jahn, O., Tenzer, S., Werner, H.
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Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]
, 2019 Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S. +7 more
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Ndrg1 in development and maintenance of the myelin sheath
Neurobiology of Disease, 2011 CMT4D disease is a severe autosomal recessive demyelinating neuropathy with extensive axonal loss leading to early disability, caused by mutations in the N-myc downstream regulated gene 1 (NDRG1). NDRG1 is expressed at particularly high levels in the Schwann cell (SC), but its physiological function(s) are unknown.
Toshiyuki Miyata +14 more
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The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]
, 2012 Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Gelain F. +9 more
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Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice
Experimental Gerontology, 2023 Pathological features of Alzheimer's Disease (AD) include alterations in the structure and function of neurons as well as of myelin sheaths. Accumulated evidence shows that aerobic type of exercise can enhance neuroplasticity in mouse models of AD ...
Dan Qiu +4 more
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eLife, 2023 Oligodendrocytes in the central nervous system exhibit significant variability in the number of myelin sheaths that are supported by each cell, ranging from 1 to 50 (1-8). Myelin production during development is dynamic and involves both sheath formation
Adam R Almeida, Wendy B Macklin
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Clemastine improves optic nerve myelin sheath regeneration and visual function in aged mice
陆军军医大学学报, 2022 Objective To investigate the changes in myelin sheath of optic nerve in mice during the process of aging and explore the effect of clemastine, a pro-myelination drug, on visual function of aging mice.
RAN Qi, CHEN Lin, YE Jian
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Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination [PDF]
, 2017 Effective bidirectional signalling between axons and Schwann cells is essential for both the development and maintenance of peripheral nerve function. We have established conditions by which human induced pluripotent stem cell-derived sensory neurons can
Bennett, David L.H. +5 more
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Stereological Methods for Estimating the Myelin Sheaths of the Myelinated Fibers in White Matter [PDF]
The Anatomical Record, 2009 AbstractIn the present study, efficient and unbiased stereological techniques to investigate the myelin sheaths of the myelinated fibers in rat white matter were established. In the present design, four tissue blocks were obtained from the entire white matter of rat brain in a uniform, random fashion.
Li, Chen +6 more
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