Myelin-like sheaths in copepod axons [PDF]
Nature, 1999 Copepods, the small planktonic crustaceans that are the most abundant metazoans in the oceans, are so successful partly because they have an escape response that accelerates them to 200 body lengths per second within milliseconds1,3. We find that nerve fibres of many copepods seem to be designed for rapid signalling.
A D, Davis +3 more
openaire +2 more sources
Effect of Sox10 on remyelination of the hippocampus in cuprizone‐induced demyelinated mice
Brain and Behavior, 2020 Objective The low number of oligodendrocytes (OLs) in the hippocampus of patients with schizophrenia suggests that hippocampal demyelination is changed in this condition. Sox10 is expressed throughout OL development.
Yu Shao +7 more
doaj +1 more source
Asymptotic construction of pulses in the Hodgkin Huxley model for myelinated nerves [PDF]
, 2005 A quantitative description of pulses and wave trains in the spatially discrete Hodgkin-Huxley model for myelinated nerves is given. Predictions of the shape and speed of the waves and the thresholds for propagation failure are obtained.
Carpio, A.
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Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]
, 2017 Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim +17 more
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Simulation of nerve fiber based on anti-resonant reflecting optical waveguide
Scientific Reports, 2022 Light and optical techniques are widely used for the diagnosis and treatment of neurological diseases as advanced methods. Understanding the optical properties of nervous tissue and nerve cells is vital.
Marzieh Omidi +2 more
doaj +1 more source
Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target
Frontiers in Immunology, 2022 Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by destruction of the myelin sheath structure.
Rongzeng Liu +10 more
doaj +1 more source
Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]
, 2019 Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S. +7 more
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eLife, 2023 Oligodendrocytes in the central nervous system exhibit significant variability in the number of myelin sheaths that are supported by each cell, ranging from 1 to 50 (1-8). Myelin production during development is dynamic and involves both sheath formation
Adam R Almeida, Wendy B Macklin
doaj +1 more source
MicroRNA-23a promotes myelination in the central nervous system. [PDF]
, 2013 Demyelinating disorders including leukodystrophies are devastating conditions that are still in need of better understanding, and both oligodendrocyte differentiation and myelin synthesis pathways are potential avenues for developing treatment ...
Fu, Ying-Hui +5 more
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Towards in vivo g-ratio mapping using MRI: unifying myelin and diffusion imaging [PDF]
, 2020 The g-ratio, quantifying the comparative thickness of the myelin sheath encasing an axon, is a geometrical invariant that has high functional relevance because of its importance in determining neuronal conduction velocity.
Callaghan, Martina F. +1 more
core +3 more sources