Deleterious functional consequences of perfluoroalkyl substances accumulation into the myelin sheath
bioRxiv, 2023 Exposure to persistent organic pollutants during the perinatal period is of particular concern because of the potential increased risk of neurological disorders in adulthood.
L. Butruille +10 more
semanticscholar +1 more source
SKAP2 as a new regulator of oligodendroglial migration and myelin sheath formation
bioRxiv, 2021 Oligodendroglial progenitor cells (OPC) are highly proliferative and migratory bipolar cells, which differentiate into complex myelin forming and axon ensheathing mature oligodendrocytes during myelination.
Julia Ghelman +5 more
semanticscholar +1 more source
Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice
Experimental Gerontology, 2023 Pathological features of Alzheimer's Disease (AD) include alterations in the structure and function of neurons as well as of myelin sheaths. Accumulated evidence shows that aerobic type of exercise can enhance neuroplasticity in mouse models of AD ...
Dan Qiu +4 more
doaj +1 more source
Advanced Maternal Age Impairs Myelination in Offspring Rats
Frontiers in Pediatrics, 2022 The effects of advanced maternal age (AMA) on the neurodevelopment of offspring are becoming increasingly important. Myelination is an important aspect of brain development; however, a limited number of studies have focused on the effects of AMA on ...
Wei Han +4 more
doaj +1 more source
Title: Effect of six-week high intensity interval training under simulated microgravity condition on morphology of radial nerve myelin sheet in male rats [PDF]
فصلنامه علوم و فناوری فضایی, 2019 The purpose of this study was to investigate the effect of six weeks of HIIT under simulated microgravity condition on morphological changes of radial nerve myelin sheath in male rats.
hossein ghadampour-vahed +3 more
doaj +1 more source
Identification of 3' UTR motifs required for mRNA localization to myelin sheaths in vivo.
PLoS Biology, 2021 Myelin is a specialized membrane produced by oligodendrocytes that insulates and supports axons. Oligodendrocytes extend numerous cellular processes, as projections of the plasma membrane, and simultaneously wrap multiple layers of myelin membrane around
Katie M Yergert +4 more
doaj +1 more source
Mechanical Responses of a Single Myelin Layer: A Molecular Simulation Study
Biomolecules, 2023 The myelin sheath provides insulation to the brain’s neuron cells, which aids in signal transmission and communication with the body. Degenerated myelin hampers the connection between the glial cells, which are the front row responders during traumatic ...
Fairuz Maliha, Ashfaq Adnan
doaj +1 more source
Neurokeratin Network of Myelin Sheaths [PDF]
Nature, 1960 THE recent communication of Tewari and Bourne1 on the neurokeratin network of peripheral nerve fibres is valuable not only for its intrinsic content but also because it validates the histological procedures, findings and arguments derived therefrom, by which it was concluded that neurokeratin formations are part of the architecture of the nerve fibres ...
M A, MACCONAILL, E, GURR
openaire +2 more sources
Microglia phagocytose myelin sheaths to modify developmental myelination [PDF]
Nature Neuroscience, 2020 During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similarly to neurons and synapses, excess myelin sheaths are produced and selectively eliminated, but how elimination occurs is unknown. Microglia, the resident immune cells of the central nervous system, engulf surplus neurons and synapses. To determine whether microglia
Alexandria N. Hughes, Bruce Appel
openaire +2 more sources
Loss of ABCA8B decreases myelination by reducing oligodendrocyte precursor cells in mice
Journal of Lipid Research, 2022 The myelin sheath, which is wrapped around axons, is a lipid-enriched structure produced by mature oligodendrocytes. Disruption of the myelin sheath is observed in several neurological diseases, such as multiple sclerosis.
Yiran Liu +14 more
doaj +1 more source