Simulation of nerve fiber based on anti-resonant reflecting optical waveguide
Light and optical techniques are widely used for the diagnosis and treatment of neurological diseases as advanced methods. Understanding the optical properties of nervous tissue and nerve cells is vital.
Marzieh Omidi+2 more
doaj +1 more source
Myelin Proteomics: Molecular Anatomy of an Insulating Sheath [PDF]
Fast-transmitting vertebrate axons are electrically insulated with multiple layers of nonconductive plasma membrane of glial cell origin, termed myelin. The myelin membrane is dominated by lipids, and its protein composition has historically been viewed to be of very low complexity.
Jahn, O., Tenzer, S., Werner, H.
openaire +4 more sources
Fibrosis imaging with multiparametric proton and sodium MRI in pig injury models
Multiparametric MRI can predict intrarenal fibrosis. ADC cortex, ΔR2*, ΔT1, the 23Na medulla/cortex ratio, and plasma creatinine resulted in the most robust model for intrarenal fibrosis prediction. Abstract Chronic kidney disease (CKD) is common and has huge implications for health and mortality.
Camilla W. Rasmussen+6 more
wiley +1 more source
Optical polarization evolution and transmission in multi-Ranvier-node axonal myelin-sheath waveguides [PDF]
In neuroscience, it is of interest to consider all possible modes of information transfer between neurons in order to fully understand processing in the brain. It has been suggested that photonic communication may be possible along axonal connections, especially through the myelin sheath as a waveguide, due to its high refractive index.
arxiv
White matter integrity in mice requires continuous myelin synthesis at the inner tongue
Myelin, the electrically insulating sheath on axons, undergoes dynamic changes over time. However, it is composed of proteins with long lifetimes. This raises the question how such a stable structure is renewed. Here, we study the integrity of myelinated
M. Meschkat+14 more
semanticscholar +1 more source
Nanoscale correlated disorder in out-of-equilibrium myelin ultrastructure [PDF]
Ultrastructural fluctuations at nanoscale are fundamental to assess properties and functionalities of advanced out-of-equilibrium materials. We have taken myelin as a model of supramolecular assembly in out-of-equilibrium living matter. Myelin sheath is a simple stable multi-lamellar structure of high relevance and impact in biomedicine. Although it is
arxiv +1 more source
Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice
Pathological features of Alzheimer's Disease (AD) include alterations in the structure and function of neurons as well as of myelin sheaths. Accumulated evidence shows that aerobic type of exercise can enhance neuroplasticity in mouse models of AD ...
Dan Qiu+4 more
doaj
Oligodendrocytes in the central nervous system exhibit significant variability in the number of myelin sheaths that are supported by each cell, ranging from 1 to 50 (1-8). Myelin production during development is dynamic and involves both sheath formation
Adam R Almeida, Wendy B Macklin
doaj +1 more source
Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer with water between the wraps. The measurement of damage to the myelin sheaths, the evaluation of the efficacy of therapies aiming to promote remyelination and ...
Chris W. J. van der Weijden+10 more
semanticscholar +1 more source
Clemastine improves optic nerve myelin sheath regeneration and visual function in aged mice
Objective To investigate the changes in myelin sheath of optic nerve in mice during the process of aging and explore the effect of clemastine, a pro-myelination drug, on visual function of aging mice.
RAN Qi, CHEN Lin, YE Jian
doaj +1 more source