Myelin-like sheaths in copepod axons [PDF]
Nature, 1999 Copepods, the small planktonic crustaceans that are the most abundant metazoans in the oceans, are so successful partly because they have an escape response that accelerates them to 200 body lengths per second within milliseconds1,3. We find that nerve fibres of many copepods seem to be designed for rapid signalling.
April D. Davis +3 more
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Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo [PDF]
, 2013 The number of myelin sheaths made by individual oligodendrocytes regulates the extent of myelination, which profoundly affects central nervous system function.
Almeida +37 more
core +2 more sources
Effect of Sox10 on remyelination of the hippocampus in cuprizone‐induced demyelinated mice
Brain and Behavior, 2020 Objective The low number of oligodendrocytes (OLs) in the hippocampus of patients with schizophrenia suggests that hippocampal demyelination is changed in this condition. Sox10 is expressed throughout OL development.
Yu Shao +7 more
doaj +1 more source
Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome [PDF]
, 2017 Rett syndrome (RTT) is a neurological disorder characterized by motor and cognitive impairment, autonomic dysfunction and a loss of purposeful hand skills.
Bahey, Noha G. +5 more
core +1 more source
Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target
Frontiers in Immunology, 2022 Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by destruction of the myelin sheath structure.
Rongzeng Liu +10 more
doaj +1 more source
Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]
, 2017 Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim +17 more
core +3 more sources
Simulation of nerve fiber based on anti-resonant reflecting optical waveguide
Scientific Reports, 2022 Light and optical techniques are widely used for the diagnosis and treatment of neurological diseases as advanced methods. Understanding the optical properties of nervous tissue and nerve cells is vital.
Marzieh Omidi +2 more
doaj +1 more source
The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]
, 2012 Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Gelain F. +9 more
core +1 more source
Myelin Proteomics: Molecular Anatomy of an Insulating Sheath [PDF]
Molecular Neurobiology, 2009 Fast-transmitting vertebrate axons are electrically insulated with multiple layers of nonconductive plasma membrane of glial cell origin, termed myelin. The myelin membrane is dominated by lipids, and its protein composition has historically been viewed to be of very low complexity.
Jahn, O., Tenzer, S., Werner, H.
openaire +4 more sources
Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]
, 2019 Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S. +7 more
core +2 more sources