Results 71 to 80 of about 48,712 (325)

Porous Decellularized Nerve Grafts Facilitate Recellularization and Nerve Regeneration in a Rat Model of Critical Long‐Gap Peripheral Nerve Injury

Advanced Healthcare Materials, EarlyView.
A decellularized nerve graft (DNG) is modified to generate a porous DNG (PDNG). The PDNG is used to repair a 30‐mm peripheral nerve injury (PNI) defect, and is compared with isograft, serving as the standard, and DNG, a widely used alternative. The result shows that PDNG facilitated nerve regeneration in long‐gap PNI, evidenced by better‐aligned axonal
Olawale Alimi Alimi, Mitchell Kuss, Wen Xue, Bo Liu, Mena Asha Krishnan, Tianshu Pan, Zhi He, Han‐Jun Wang, Yuguo Lei, Kai Yang, Bin Duan   +10 more
wiley   +1 more source

Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP.

PLoS Genetics, 2016
Schwann cells in the peripheral nervous systems extend their membranes to wrap axons concentrically and form the insulating sheath, called myelin. The spaces between layers of myelin are sealed by myelin junctions.
Bo Hu, Sezgi Arpag, Xuebao Zhang, Wiebke Möbius, Hauke Werner, Gina Sosinsky, Mark Ellisman, Yang Zhang, Audra Hamilton, Jonathan Chernoff, Jun Li   +10 more
doaj   +1 more source

Interaction of PLP with GFP-MAL2 in the human oligodendroglial cell line HOG. [PDF]

PLoS ONE, 2011
The velocity of the nerve impulse conduction of vertebrates relies on the myelin sheath, an electrically insulating layer that surrounds axons in both the central and peripheral nervous systems, enabling saltatory conduction of the action potential ...
Raquel Bello-Morales, Raquel Bello-Morales, Marta Pérez-Hernández, María Teresa Rejas, Fuencisla Matesanz, Antonio Alcina, José Antonio López-Guerrero   +6 more
doaj   +1 more source

A physical perspective to understand myelin. I. A physical answer to Peter’s quadrant mystery

Frontiers in Neuroscience, 2022
In the development of oligodendrocytes in the central nervous systems, the inner and outer tongue of the myelin sheath tend to be located within the same quadrant, which was named as Peters quadrant mystery.
Yonghong Liu, Wenji Yue, Shoujun Yu, Tian Zhou, Yapeng Zhang, Ran Zhu, Bing Song, Tianruo Guo, Fenglin Liu, Yubin Huang, Tianzhun Wu, Tianzhun Wu, Hao Wang, Hao Wang   +13 more
doaj   +1 more source

Pathological classification of equine recurrent laryngeal neuropathy [PDF]

, 2018
Recurrent Laryngeal Neuropathy (RLN) is a highly prevalent and predominantly left‐sided, degenerative disorder of the recurrent laryngeal nerves (RLn) of tall horses, that causes inspiratory stridor at exercise because of intrinsic laryngeal muscle ...
Draper, A C E, Piercy, R J
core   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo [PDF]

, 2013
The number of myelin sheaths made by individual oligodendrocytes regulates the extent of myelination, which profoundly affects central nervous system function.
Almeida, Brinkmann, Charles ffrench-Constant, Chong, Czopka, David A. Lyons, Dawson, Fields, Franklin, Franklin, Fünfschilling, Jopling, Kang, Kirby, Krämer-Albers, Kwan, Lamason, Laursen, Lee, Liu, Makinodan, Miller, Nave, Ng, Park, Provost, Remahl, Richardson, Savas, Sherman, Tim Czopka, Umemori, Wake, Watkins, White, Young, Zatorre, Zawadzka   +37 more
core   +2 more sources

Junctions tighten myelin sheaths

The Journal of Cell Biology, 2005
![][1] Claudin-19 (green) helps form tight junction structures that seal PNS myelin sheaths. Tight junction-like structures run along myelin sheaths in both the central and peripheral nervous systems (CNS and PNS), but have only been functionally characterized in the CNS.
openaire   +3 more sources

3D Printing of Conducting Polymer Hydrogels for Electrostimulation‐Assisted Tissue Engineering

Advanced Materials, EarlyView.
This review highlights nanosized inherently conducting polymers (ICPs) as promising ink constituents for 3D printing of conducting hydrogel (CH)‐based electrostimulation (ES) devices. ICP‐based ink formulation, 3D printing, and solidification strategies are discussed, along with the application of 3D‐printed ICP‐based CHs as ES platforms for regulating
Chien Minh Tran, Zhilian Yue, Chunyan Qin, Kusuma B. C. Imani, Mirella Dottori, Robert J. Forster, Gordon G. Wallace   +6 more
wiley   +1 more source

Bioengineered Models of Nerve Regeneration

Advanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson, John Paul Frampton   +1 more
wiley   +1 more source