Results 231 to 240 of about 43,839 (265)
Sleep Health and White Matter Integrity in the UK Biobank
ABSTRACT Many people experience impaired sleep health, yet knowledge about its neurobiological correlates is limited. As previous studies have found associations between white matter integrity and several sleep traits, white matter integrity could be causally implicated in poor sleep health.
Roxana Petri+8 more
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Questioning the pros and cons of metformin treatment in diabetic peripheral neuropathy
Journal of Diabetes Investigation, EarlyView.
Hiroki Mizukami
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Myelination in the absence of myelin-associated glycoprotein [PDF]
The hypothesis that myelin-associated glycoprotein (MAG) initiates myelin formation is based in part on observations that MAG has an adhesive role in interactions between oligodendrocytes and neurons. Furthermore, the over- or underexpression of MAG in transfected Schwann cells in vitro leads to accelerated myelination or hypomyelination, respectively.
Michael B. Tropak+7 more
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Axon Myelination: Myelination without myelin-associated glycoprotein
Current Biology, 1994Mice lacking myelin-associated glycoprotein surprisingly myelinate almost normally but their oligodendrocytes have lost their periaxonal cytoplasmic 'collars' and accidentally myelinate already-myelinated axons.
Anke Meyer-Franke, Barbara Barres
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To Myelinate or Not to Myelinate?
2010Myelinated and non-myelinated axons co-exist in the brain. What determines whether an axon should be myelinated or not? Rushton proposed that among myelinated and non-myelinated alternatives with the same conduction velocity (CV), a thinner fiber is chosen due to its smaller volume cost.
Quan Wen, Quan Wen, Dmitri B. Chklovskii
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The anatomy and biochemistry of myelin and myelination
Operative Techniques in Orthopaedics, 2004Despite advances in peripheral nerve repair techniques, complete functional recovery is seldom achieved. To understand the nerve’s regenerative capacity, it is necessary to understand its developmental and functional anatomy and its cellular constituents.
Ranjan Gupta+2 more
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Myelination and Retarded Myelination
1989Flechsig (1920) was the originator of the view that the degree of myelination of the central nervous system might be correlated with functional capacity. In his theory he stated that myelination started in projection pathways before association pathways, in peripheral nerves before central pathways, and in sensory areas before motor ones.
Marjo S. van der Knaap, Jacob Valk
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Myelin, myelin-related disorders, and psychosis
Schizophrenia Research, 2015The neuropathological basis of schizophrenia and related psychoses remains elusive despite intensive scientific investigation. Symptoms of psychosis have been reported in a number of conditions where normal myelin development is interrupted. The nature, location, and timing of white matter pathology seem to be key factors in the development of ...
Michelle I. Mighdoll+3 more
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Current Opinion in Neurobiology, 1993
Myelin formation and maintenance requires complex interactions between neurons and glia, and between the integral protein and lipid components of the myelin sheath. Many of the underlying mechanisms may be examined by studying the perturbations caused by spontaneous and targeted mutations in myelin protein genes.
Ueli Suter+5 more
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Myelin formation and maintenance requires complex interactions between neurons and glia, and between the integral protein and lipid components of the myelin sheath. Many of the underlying mechanisms may be examined by studying the perturbations caused by spontaneous and targeted mutations in myelin protein genes.
Ueli Suter+5 more
openaire +3 more sources
Morphological Aspects of Myelin and Myelination [PDF]
Myelin is a membrane characteristic of the vertebrate nervous system, laid down in segments along selected nerve fibers, functioning as an insulator to increase the velocity of stimuli being transmitted between a nerve cell body and its target. Myelin is morphologically unique, and, while the present section will highlight this uniqueness, it is ...
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