Results 71 to 80 of about 72,709 (299)
Journal of Cell Science, 2014 ABSTRACTThe myelin sheath is a plasma membrane extension that is laid down in regularly spaced segments along axons of the nervous system. This process involves extensive changes in oligodendrocyte cell shape and membrane architecture. In this Cell Science at a Glance article and accompanying poster, we provide a model of how myelin of the central ...
Snaidero, N., Simons, M.
openaire +4 more sources
Schwann cell myelination requires Dynein function [PDF]
, 2012 Background Interaction of Schwann cells with axons triggers signal transduction that drives expression of Pou3f1 and Egr2 transcription factors, which in turn promote myelination.
Appel Bruce, Langworthy Melissa M
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Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Advanced Science, EarlyView.Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
Frontiers in Neurology, 2018 BackgroundIron deficiency is the most common micronutrient deficiency worldwide and children are at an increased risk due to the rapid growth occurring during early life.
Austin T. Mudd +10 more
doaj +1 more source
Investigating endothelin receptor B signalling during myelination [PDF]
, 2017 A key process enabling the correct functioning of neural circuits involves the formation of multi‐layered membranous myelin sheaths around axons. Myelin sheaths, made by specialised glial cells called oligodendrocytes in the central nervous system ...
Swire, Matthew
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Vimentin regulates peripheral nerve myelination [PDF]
, 2012 Myelination is a complex process that requires coordinated Schwann cell-axon interactions during development and regeneration. Positive and negative regulators of myelination have been recently described, and can belong either to Schwann cells or neurons.
Taveggia C +11 more
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Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation
Advanced Science, EarlyView.A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou +12 more
wiley +1 more source
Emerging Role of Schwann Cells in Neuropathic Pain: Receptors, Glial Mediators and Myelination
Frontiers in Cellular Neuroscience, 2019 Neuropathic pain caused by nerve injury or disease remains a major challenge for modern medicine worldwide. Most of the pathogenic mechanisms underlying neuropathic pain are centered on neuronal mechanisms.
Zhongya Wei +4 more
doaj +1 more source
On the Myelination of GABAergic Interneurons [PDF]
, 2019 Myelination is the insulating ensheathment of axons by oligodendrocytes to increase action potential propagation and provide metabolic support. GABAergic interneurons are a heterogeneous group of predominantly local, inhibitory cells. In schizophrenia, a
Stedehouder, J. (Jeffrey) +1 more
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TrkB Signaling and Fluoxetine in Parvalbumin Interneuron Myelination [PDF]
, 2023 Myelin is a lipid-rich substance wrapped around nerve axons that can be adaptively modified in response to neuronal activity and experience. Recent research has revealed myelination of parvalbumin (PV) inhibitory interneurons, critical for brain ...
Maiju, Savolainen
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