Results 61 to 70 of about 77,821 (298)

MRI diagnosis of cortical dysplasia in the immature brain

open access: yesЭпилепсия и пароксизмальные состояния, 2020
Introduction. Cortical dysplasias (CDs) encompass a wide variety of disorders that in most cases lead to epilepsy, especially in infants and young children.
M. V. Polyanskaya   +7 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

Supplementation with complex milk lipids during brain development promotes neuroplasticity without altering myelination or vascular density

open access: yesFood & Nutrition Research, 2015
Background: Supplementation with complex milk lipids (CML) during postnatal brain development has been shown to improve spatial reference learning in rats.
Rosamond B. Guillermo   +4 more
doaj   +1 more source

Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis

open access: yeseLife, 2021
Myelination depends on timely, precise control of oligodendrocyte differentiation and myelinogenesis. Cholesterol is the most abundant component of myelin and essential for myelin membrane assembly in the central nervous system.
Xin Zhou   +13 more
doaj   +1 more source

The history of myelin [PDF]

open access: yesExperimental Neurology, 2016
Andreas Vesalius is attributed the discovery of white matter in the 16th century but van Leeuwenhoek is arguably the first to have observed myelinated fibers in 1717. A globular myelin theory followed, claiming all elements of the nervous system except for Fontana's primitive cylinder with outer sheath in 1781. Remak's axon revolution in 1836 relegated
openaire   +2 more sources

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

open access: yesAdvanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn   +17 more
wiley   +1 more source

Targeting enhancing myelin regeneration reverses cognitive deficits in a mouse model of intellectual disability

open access: yesNeurotherapeutics
The early postnatal period is a critical window for brain maturation, during which oligodendrogenesis, myelination, and synaptogenesis are dynamically orchestrated to support cognitive development.
Pingping Qiao   +9 more
doaj   +1 more source

Dietary Iron Repletion following Early-Life Dietary Iron Deficiency Does Not Correct Regional Volumetric or Diffusion Tensor Changes in the Developing Pig Brain

open access: yesFrontiers in Neurology, 2018
BackgroundIron deficiency is the most common micronutrient deficiency worldwide and children are at an increased risk due to the rapid growth occurring during early life.
Austin T. Mudd   +10 more
doaj   +1 more source

Microfiber platform for oligodendrocyte myelination

open access: yes, 2019
Injuries or disorders in the central nervous system disrupt crucial sensory and motor functions. This critical system has limited regenerative capability, often contributes directly to permanent disabilities in afflicted adults.
Ong, William
core   +1 more source

HIFα Regulates Developmental Myelination Independent of Autocrine Wnt Signaling. [PDF]

open access: yes, 2021
The developing CNS is exposed to physiological hypoxia, under which hypoxia-inducible factor α (HIFα) is stabilized and plays a crucial role in regulating neural development.
Deng, Wenbin   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy