Results 41 to 50 of about 72,709 (299)
Nature Communications, 2020 Myelination by Schwann cells (SC) in the peripheral nervous system is essential for motor function, and dysregulation of SC myelination can lead to various neuropathies.
Jincheng Wang +9 more
doaj +1 more source
Polyphosphoinositides in myelin [PDF]
Biochemical Journal, 1965 1. On fractionation of guinea-pig forebrain homogenates by differential and gradient-density centrifugation most of the polyphosphoinositides were recovered in the myelin-rich particles. 2. The phospholipids of pure preparations of myelin contained di- and tri-phosphoinositide in proportions 2-3 times greater than in the whole-brain phospholipids.
J, Eichberg, R M, Dawson
openaire +2 more sources
Functional duality of astrocytes in myelination [PDF]
, 2011 Astrocytes undergo major phenotypic changes in response to injury and disease that directly influence repair in the CNS, but the mechanisms involved are poorly understood. Previously, we have shown that neurosphere-derived rat astrocytes plated on poly-L-
McClure, J.D. +13 more
core +1 more source
Schwann cell spectrins modulate peripheral nerve myelination [PDF]
, 2011 During peripheral nerve development, Schwann cells ensheathe axons and form myelin to enable rapid and efficient action potential propagation. Although myelination requires profound changes in Schwann cell shape, how neuron–glia interactions converge on ...
Matthew N. Rasband +6 more
core +1 more source
Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber
Cell Reports, 2018 Summary: Emerging evidence suggests that neuronal signaling is important for oligodendrocyte myelination; however, the necessity of this signaling during development is unclear.
Sonia R. Mayoral +3 more
doaj +1 more source
Dynamics and Mechanisms of CNS Myelination [PDF]
, 2015 Vertebrate myelination is an evolutionary advancement essential for motor, sensory, and higher-order cognitive function. CNS myelin, a multilamellar differentiation of the oligodendrocyte plasma membrane, ensheaths axons to facilitate electrical ...
Bercury, Kathryn K., Macklin, Wendy B.
core +1 more source
PLoS ONE, 2013 The timing and progression of axonal myelination are precisely controlled by intercellular interactions between neurons and glia in development. Previous in vitro studies demonstrated that Nectin like 4 (Necl-4, also known as cell adhesion molecule Cadm ...
Ying Zhu +12 more
doaj +1 more source
Role of tumor necrosis factor-alpha in zebrafish retinal neurogenesis and myelination [PDF]
International Journal of Ophthalmology, 2016 AIM: To investigate the role of tumor necrosis factor-alpha (TNF-α) in zebrafish retinal development and myelination. METHODS: Morpholino oligonucleotides (MO), which are complementary to the translation start site of the wild-type embryonic zebrafish ...
Xu-Dan Lei +5 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Tau is abundantly expressed in neurons, however previous reports and our recent study showed tau also exist in oligodendrocytes. Also the expression levels of tau are dramatical changed in hypomyelination model rat and in demyelination region of stroke ...
Tomohiro Torii +5 more
doaj +1 more source
HIFα Regulates Developmental Myelination Independent of Autocrine Wnt Signaling. [PDF]
, 2021 The developing CNS is exposed to physiological hypoxia, under which hypoxia-inducible factor α (HIFα) is stabilized and plays a crucial role in regulating neural development.
Deng, Wenbin +5 more
core +1 more source