Results 31 to 40 of about 77,821 (298)
Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
Data in Brief, 2017 Cytohesin-1 is the guanine-nucleotide exchange factor of Arf6, a small GTPase of Arf family, and participates in cellular morphological changes. Knockout mice of cytohesin-1 exhibit decreased myelination of neuronal axons in the peripheral nervous system
Ruri Tsuneishi +11 more
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Fushe yanjiu yu fushe gongyi xuebao, 2021 A rat radiation injury model was constructed, in which myelin basic protein (MBP) expression was detected via western blot. Primary oligodendrocyte precursor cells (OPCs) and neuronal cells were isolated from Sprague-Dawley rats, and expression of ...
WANG Yanyan +5 more
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Is Myelin a Mitochondrion? [PDF]
Journal of Cerebral Blood Flow & Metabolism, 2012 It has been hypothesized that myelin acts like a mitochondrion, generating ATP across the membranes of its sheath. By calculating the proton motive force across the myelin membrane based on known values for the pH and membrane potential of the oligodendrocyte, we find that insufficient energy could be harvested from proton flow across the myelin ...
Harris, Julia J, Attwell, David
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Assessment of normal myelination in infants and young children using the T1w/T2w mapping technique
Frontiers in Neuroscience, 2023 BackgroundWhite matter myelination is a crucial process of CNS maturation. The purpose of this study was to validate the T1w/T2w mapping technique for brain myelination assessment in infants and young children.MethodsNinety-four patients (0–23 months of ...
Elena Filimonova +9 more
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Axon-glia interactions during central nervous system myelination [PDF]
, 2015 Myelination drastically speeds up action potential propagation along axons, which is fundamental for the correct function of neuronal circuits. However, axon-oligodendrocyte interactions regulating the onset of myelin formation remain unclear.
Almeida, Rafael
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Frontiers in Cellular Neuroscience, 2021 The benefits of transplanting cultured Schwann cells (SCs) for the treatment of spinal cord injury (SCI) have been systematically investigated in experimental animals since the early 1990s. Importantly, human SC (hSC) transplantation for SCI has advanced
Paula V. Monje +5 more
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Nature Communications, 2020 Myelination by Schwann cells (SC) in the peripheral nervous system is essential for motor function, and dysregulation of SC myelination can lead to various neuropathies.
Jincheng Wang +9 more
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Neuron, 2017 Long non-coding RNAs (lncRNAs) have been implicated in numerous developmental processes. In a technical and bioinformatics tour-de-force, He et al. (2017) provide critical insight into the dynamics of lncRNA expression, function, and mechanism during oligodendrocyte development and after injury.
Stacey M, Glasgow, Benjamin, Deneen
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Social Experience-Dependent Myelination: An Implication for Psychiatric Disorders
Neural Plasticity, 2015 Myelination is one of the strategies to promote the conduction velocity of axons in order to adjust to evolving environment in vertebrates. It has been shown that myelin formation depends on genetic programing and experience, including multiple factors ...
Michihiro Toritsuka +2 more
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Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber
Cell Reports, 2018 Summary: Emerging evidence suggests that neuronal signaling is important for oligodendrocyte myelination; however, the necessity of this signaling during development is unclear.
Sonia R. Mayoral +3 more
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