Results 11 to 20 of about 77,821 (298)
Myelin is a key evolutionary acquisition that underlay the development of the large, complex nervous systems of all hinged-jaw vertebrates. By promoting rapid, efficient nerve conduction, myelination also made possible the development of the large body size of these vertebrates.
Salzer, J.L., Zalc, B.
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Bihemispheric alterations in myelination in children following unilateral perinatal stroke
Background: Stroke is a leading cause of perinatal brain injury with variable outcomes including cerebral palsy and epilepsy. The biological processes that underlie these heterogeneous outcomes are poorly understood.
Sabrina Yu +7 more
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Neuron–Oligodendrocyte Communication in Myelination of Cortical GABAergic Cells
Axonal myelination by oligodendrocytes increases the speed and reliability of action potential propagation, and so plays a pivotal role in cortical information processing.
Elisa Mazuir +2 more
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The dual role of astrocytes in myelination [PDF]
Astrocytes are the most abundant cell within the central nervous system (CNS) and yet despite this, the true extent of their role in health and disease has not been fully elucidated.
Nash, Besma
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Overview of myelin, major myelin lipids, and myelin-associated proteins
Myelin is a modified cell membrane that forms a multilayer sheath around the axon. It retains the main characteristics of biological membranes, such as lipid bilayer, but differs from them in several important respects. In this review, we focus on aspects of myelin composition that are peculiar to this structure and differentiate it from the more ...
Alexander Kister, Ilya Kister
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Myelin lipid metabolism and its role in myelination and myelin maintenance
Myelin is a specialized cell membrane indispensable for rapid nerve conduction. The high abundance of membrane lipids is one of myelin's salient features that contribute to its unique role as an insulator that electrically isolates nerve fibers across their myelinated surface.
Joseph A. Barnes-Vélez +2 more
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Time-lapse imaging of the dynamics of CNS glial-axonal interactions in vitro and ex vivo [PDF]
<b>Background</b> Myelination is an exquisite and dynamic example of heterologous cell-cell interaction, which consists of the concentric wrapping of multiple layers of oligodendrocyte membrane around neuronal axons.
Strachan, D. +19 more
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Functional role of the overexpression of the myelin and lymphocyte protein MAL in Schwann cells [PDF]
For fast propagation of action potentials in the nervous system, higher vertebrates have developed a specialized plasma membrane structure, the myelin, ensheathing nerve fibers. Myelin sheaths are formed by Schwann cells in the peripheral nervous system (
Schmid, Daniela
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The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]
Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Boomkamp, S.D. +13 more
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The development of neuronal circuitry required for cognition, complex motor behaviors, and sensory integration requires myelination. The role of glial cells such as astrocytes and microglia in shaping synapses and circuits have been covered in other ...
Daniela M. S. Moura +4 more
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