Results 261 to 270 of about 162,344 (302)

Modulating phosphodiesterase-5 activity to suppress the immunosuppressive mechanisms of myeloid-derived suppressor cells in breast cancer. [PDF]

Breast Cancer Res
Guo Y, Chen M, Yuan Q, Huang J, Mao W, Liu X, Jin L, Chen L, Lou J, Liu X, Pan Q, Fu H, Shou Q.   +12 more
europepmc   +1 more source

Identifying Myeloid-Derived Suppressor Cells and Lipocalin-2 as Therapeutic Targets for Intervertebral Disc Degeneration. [PDF]

Adv Sci (Weinh)
Zhang C, Li H, Wang H, Shi L, Chan YS, Wang Y, Shea GKH.   +6 more
europepmc   +1 more source

Chronic stress drives ovarian cancer progression via myeloid-derived suppressor cells infiltration and Notch signaling pathway activation. [PDF]

Front Immunol
Rivera-López YA, Torres-Rosado AP, Casiano-Martínez JA, Meléndez-Rodríguez LL, Imad-Hamad R, Hernández-Carrasquillo SM, Rivera-Pérez LM, Ortiz-León M, Torres-Rodríguez OI, Aquino-Acevedo AN, Castillo-Ocampo Y, Duffey G, Pérez-Morales J, Townsend MK, Peres LC, Rodriguez PC, Tworoger SS, Armaiz-Pena GN.   +17 more
europepmc   +1 more source

Myeloid-Derived Suppressor Cells (MDSCs) Suppress T-Cell Proliferation Less Than Mature Neutrophils in Blood and Bone Marrow From Multiple Myeloma Patients. [PDF]

J Immunol Res
Westerlund J, Askman S, Pettersson Å, Wichert S, Hellmark T, Johansson ÅCM, Hansson M.   +6 more
europepmc   +1 more source

Effect of myeloid-derived suppressor cells on retinal epithelial cells in retinopathy of prematurity model. [PDF]

Transl Pediatr
Huang W, Ou Q, Liu Y, Hu J, Wang L.
europepmc   +1 more source

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Myeloid-Derived Suppressor Cells and Radiotherapy

Cancer Immunology Research, 2022
Abstract Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of pathologically activated, mostly immature, myeloid cells that exert robust immunosuppressive functions. MDSCs expand during oncogenesis and have been linked to accelerated disease progression and resistance to treatment in both preclinical tumor models ...
Carlos Jiménez-Cortegana, Claudia Galassi, Vanessa Klapp, Dmitry I. Gabrilovich, Lorenzo Galluzzi   +4 more
openaire   +2 more sources

Myeloid-Derived Suppressor Cells

2007
The development of tumor-specific T cell tolerance is largely responsible for tumor escape. Accumulation of myeloid-derived suppressor cells (MDSCs) in animal tumor models as well as in cancer patients is involved in tumor-associated T cell tolerance.
Srinivas, Nagaraj, Dmitry I, Gabrilovich
openaire   +2 more sources

Myeloid derived suppressor cells in transplantation

Current Opinion in Immunology, 2011
Myeloid derived suppressor cells (MDSC) are a heterogeneous population of hematopoietic derived cell precursors that can suppress immune responses in a variety of inflammatory settings. Here we review recent studies detailing expansion of phenotypically and functionally disparate MDSC.
Jason R, Lees, Agnes M, Azimzadeh, Jonathan S, Bromberg   +2 more
openaire   +2 more sources

Myeloid-derived suppressor cells in glioma

Expert Review of Neurotherapeutics, 2013
Glioblastoma is the most prevalent form of gliomas with high aggressive nature and high recurrence. Despite aggressive therapy, including surgery, chemotherapy and radiotherapy, median patient survival is only about 15 months. Hence, developing novel and efficient therapies seem urgent.
Masoud, Mirghorbani, Stefaan, Van Gool, Nima, Rezaei   +2 more
openaire   +2 more sources