Results 1 to 10 of about 43,753 (301)

Generation and functional characterization of MDSC-like cells

open access: yesOncoImmunology, 2017
Myeloid-derived suppressor cells (MDSC) are critical in regulating immune responses by suppressing antigen presenting cells (APC) and T cells. We previously observed that incubation of peripheral blood monocytes with interleukin (IL)-10 during their ...
Annkristin Heine   +10 more
doaj   +2 more sources

TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy

open access: yesOncoImmunology, 2018
Cancer-induced myeloid-derived suppressor cells (MDSC) play an important role in tumor immune evasion. MDSC programming or polarization has been proposed as a strategy for leveraging the developmental plasticity of myeloid cells to reverse MDSC immune ...
Padmini Jayaraman   +15 more
doaj   +2 more sources

KIRA6 restrains the generation of myeloid-derived suppressor cells and overcomes resistance to anti-PD-1 therapy [PDF]

open access: yesCell Death and Disease
Immune checkpoint blockade (ICB) therapy is one of the cornerstones of cancer treatment regimens, but the overall response rates remain low because of suppressive immune cells, such as myeloid-derived suppressor cells (MDSC).
Chun Chen   +13 more
doaj   +2 more sources

Evaluation The Role of CD33+ CD11b+ myeloid-derived Suppressor Cells in Patients With AML [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2022
Acute myeloid leukemia is a genetically heterogeneous clonal disease defined by the accumulation of immature cells in bone marrow and blood. The aim of this study is to evaluate the CD33, CD11b, and HLA-DR expression in Iraqi AML patients and its role in
Hala Hamad, Zeyad Shabeeb, Muthanna Awad
doaj   +1 more source

Experiment on wax precipitation property of waxy crude oil based on DSC

open access: yesYou-qi chuyun, 2023
Wax precipitation property of waxy crude oil is a basic parameter for the economic & safe operation and flow security assurance technology of waxy crude oil pipeline transportation.
GUO Liping, YI Bo, CHEN Rui, FENG Yaoguo
doaj   +1 more source

Cisplatin inhibits frequency and suppressive activity of monocytic myeloid-derived suppressor cells in cancer patients

open access: yesOncoImmunology, 2021
Cancer immunotherapies have induced long-lasting responses in cancer patients including those with melanoma and head and neck squamous cell carcinoma (HNSCC).
Glenn F. Van Wigcheren   +11 more
doaj   +1 more source

Changes in myoglobin content in pork Longissimus thoracis muscle during freezing storage

open access: yesRevista Mexicana de Ciencias Pecuarias, 2020
In this study, pork Longissimus thoracis muscle was used, which was frozen in a chamber and thawed under controlled conditions. The color profile and the surface myoglobin were evaluated.
Jonathan Coria-Hernández   +3 more
doaj   +1 more source

Effect of Immune Checkpoint Blockade on Myeloid-Derived Suppressor Cell Populations in Patients With Melanoma

open access: yesFrontiers in Immunology, 2021
IntroductionMyeloid-derived suppressor cells (MDSC) are a subset of immature myeloid cells that inhibit anti-tumor immunity and contribute to immune therapy resistance.
Steven H. Sun   +18 more
doaj   +1 more source

Prevalence of malocclusion traits in an Australian adult population

open access: yesAustralasian Orthodontic Journal, 1997
The prevalence of certain malocclusion traits in an Australian adult population was examined in a sample of 113 female and 103 male adult subjects aged between 18 and 64 years (average age = 38.1 years).
Tod Marcus A., Taverne Aart A.R.
doaj   +1 more source

The prognostic value and therapeutic targeting of myeloid-derived suppressor cells in hematological cancers

open access: yesFrontiers in Immunology, 2022
The success of immunotherapeutic approaches in hematological cancers is partially hampered by the presence of an immunosuppressive microenvironment.
Rong Fan   +8 more
doaj   +1 more source

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