Results 1 to 10 of about 36,927 (297)

M-MDSC in vitro generation from mouse bone marrow with IL-3 reveals high expression and functional activity of arginase 1

open access: yesFrontiers in Immunology, 2023
Myeloid-derived suppressor cells (MDSC) represent major regulators of immune responses, which can control T cells via their inducible nitric oxide synthase (iNOS)- and arginase 1 (Arg1)-mediated effector functions.
Manfred B Lutz   +2 more
exaly   +4 more sources

Generation and functional characterization of MDSC-like cells

open access: yesOncoImmunology, 2017
Myeloid-derived suppressor cells (MDSC) are critical in regulating immune responses by suppressing antigen presenting cells (APC) and T cells. We previously observed that incubation of peripheral blood monocytes with interleukin (IL)-10 during their ...
Niklas A Schmacke   +2 more
exaly   +2 more sources

A novel MDSC-induced PD-1−PD-L1+ B-cell subset in breast tumor microenvironment possesses immuno-suppressive properties

open access: yesOncoImmunology, 2018
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid cells that suppress T-cell activity in a tumor microenvironment. However, the suppressive function of MDSCs on B cells and its underlying mechanism remain unclear.
Xiubao Ren, Feng Wei, Shizhen Emily Wang
exaly   +2 more sources

Evaluation The Role of CD33+ CD11b+ myeloid-derived Suppressor Cells in Patients With AML [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2022
Acute myeloid leukemia is a genetically heterogeneous clonal disease defined by the accumulation of immature cells in bone marrow and blood. The aim of this study is to evaluate the CD33, CD11b, and HLA-DR expression in Iraqi AML patients and its role in
Hala Hamad, Zeyad Shabeeb, Muthanna Awad
doaj   +1 more source

Experiment on wax precipitation property of waxy crude oil based on DSC

open access: yesYou-qi chuyun, 2023
Wax precipitation property of waxy crude oil is a basic parameter for the economic & safe operation and flow security assurance technology of waxy crude oil pipeline transportation.
GUO Liping, YI Bo, CHEN Rui, FENG Yaoguo
doaj   +1 more source

Cisplatin inhibits frequency and suppressive activity of monocytic myeloid-derived suppressor cells in cancer patients

open access: yesOncoImmunology, 2021
Cancer immunotherapies have induced long-lasting responses in cancer patients including those with melanoma and head and neck squamous cell carcinoma (HNSCC).
Glenn F. Van Wigcheren   +11 more
doaj   +1 more source

Changes in myoglobin content in pork Longissimus thoracis muscle during freezing storage

open access: yesRevista Mexicana de Ciencias Pecuarias, 2020
In this study, pork Longissimus thoracis muscle was used, which was frozen in a chamber and thawed under controlled conditions. The color profile and the surface myoglobin were evaluated.
Jonathan Coria-Hernández   +3 more
doaj   +1 more source

Effect of Immune Checkpoint Blockade on Myeloid-Derived Suppressor Cell Populations in Patients With Melanoma

open access: yesFrontiers in Immunology, 2021
IntroductionMyeloid-derived suppressor cells (MDSC) are a subset of immature myeloid cells that inhibit anti-tumor immunity and contribute to immune therapy resistance.
Steven H. Sun   +18 more
doaj   +1 more source

Prevalence of malocclusion traits in an Australian adult population

open access: yesAustralasian Orthodontic Journal, 1997
The prevalence of certain malocclusion traits in an Australian adult population was examined in a sample of 113 female and 103 male adult subjects aged between 18 and 64 years (average age = 38.1 years).
Tod Marcus A., Taverne Aart A.R.
doaj   +1 more source

The prognostic value and therapeutic targeting of myeloid-derived suppressor cells in hematological cancers

open access: yesFrontiers in Immunology, 2022
The success of immunotherapeutic approaches in hematological cancers is partially hampered by the presence of an immunosuppressive microenvironment.
Rong Fan   +8 more
doaj   +1 more source

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