Results 41 to 50 of about 43,753 (301)

Key Candidate Prognostic Biomarkers Correlated with Immune Infiltration in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2021
Zenghua Deng,1,2,* Kanghua Huang,3,* Dongfang Liu,1 Nan Luo,1,2 Tingting Liu,1 Long Han,1 Dexiao Du,1 Dongbo Lian,1,2 Zhaohui Zhong,4 Jirun Peng1,2 1Department of Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038 ...
Deng Z, Huang K, Liu D, Luo N, Liu T, Han L, Du D, Lian D, Zhong Z, Peng J   +9 more
doaj  

Review on system and materials requirements for high temperature thermal energy storage. Part 1: General requirements [PDF]

, 2016
High temperature thermal energy storage offers a huge energy saving potential in industrial applications such as solar energy, automotive, heating and cooling, and industrial waste heat recovery. However, certain requirements need to be faced in order to
Cabeza, Luisa F., Gasia, Jaume, Miró, Laia   +2 more
core   +2 more sources

Myth or Truth: The Glass Forming Ability Class III Drugs Will Always Form Single-Phase Homogenous Amorphous Solid Dispersion Formulations

Pharmaceutics, 2019
The physical stability of amorphous solid dispersions (ASD) of active pharmaceutical ingredients (APIs) of high glass forming ability (GFA class III) is generally expected to be high among the scientific community.
Piyush Panini, Massimiliano Rampazzo, Abhishek Singh, Filip Vanhoutte, Guy Van den Mooter   +4 more
doaj   +1 more source

Differential induction of Ly6G and Ly6C positive myeloid derived suppressor cells in chronic kidney and liver inflammation and fibrosis. [PDF]

PLoS ONE, 2015
CD11b+Gr1+ myeloid derived suppressor cells (MDSC) are known to be very potent suppressors of T cell immunity and can be further stratified into granulocytic MDSC and monocytic MDSC in mice based on expression of Ly6G or Ly6C, respectively.
Bastian Höchst, Julita Mikulec, Tania Baccega, Christina Metzger, Meike Welz, Julia Peusquens, Frank Tacke, Percy Knolle, Christian Kurts, Linda Diehl, Isis Ludwig-Portugall   +10 more
doaj   +1 more source

PMN-MDSC in newborns: Regulation of the regulators

Journal of Leukocyte Biology, 2022
AbstractPMN-MDSC are pathologically activated neutrophils that acquire T cell (and NK cell) suppressive activity and thus function as negative regulators of effector lymphocytes in many disease conditions.[1] For many years, these PMN-MDSC have mainly been seen as contributors to disease progression and severity, best exemplified in the context of ...
Jablonska, Jadwiga, Brandau, Sven
openaire   +3 more sources

Upregulated TRAIL and Reduced DcR2 Mediate Apoptosis of Decidual PMN-MDSC in Unexplained Recurrent Pregnancy Loss

Frontiers in Immunology, 2020
Myeloid-derived suppressor cells (MDSC), especially polymorphonuclear MDSC (PMN-MDSC), accumulate in maternal-fetal interface during pregnancy and are involved in the maintenance of immune tolerance.
Congcong Li, Congcong Li, Xiaoxin Zhang, Xiaomin Kang, Chao Chen, Chao Chen, Feng Guo, Feng Guo, Qiaohong Wang, Qiaohong Wang, Aimin Zhao, Aimin Zhao   +11 more
doaj   +1 more source

Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia

Haematologica, 2022
Myeloid-derived suppressor cells (MDSC) are a group of heterogeneous immature myeloid cells and display immunosuppressive function. In this study, MDSC populations were evaluated in acquired aplastic anemia (AA) (n=65) in which aberrant immune ...
Peiyuan Dong, Lingyun Chen, Hongfei Wu, Jiali Huo, Zhongxing Jiang, Yingqi Shao, Xiang Ren, Jinbo Huang, Xingxin Li, Min Wang, Neng Nie, Jing Zhang, Peng Jin, Yizhou Zheng, Meili Ge   +14 more
doaj   +1 more source

MDSCs in infectious diseases: regulation, roles, and readjustment [PDF]

Cancer Immunology, Immunotherapy, 2018
Many pathogens, ranging from viruses to multicellular parasites, promote expansion of MDSCs, which are myeloid cells that exhibit immunosuppressive features. The roles of MDSCs in infection depend on the class and virulence mechanisms of the pathogen, the stage of the disease, and the pathology associated with the infection. This work compiles evidence
Dorhoi, Anca, Glaría, Estibaliz, Garcia-Tellez, Thalia, Nieuwenhuizen, Natalie E, Zelinskyy, Gennadiy, Favier, Benoit, Singh, Anurag, Ehrchen, Jan, Gujer, Cornelia, Münz, Christian, Saraiva, Margarida, Sohrabi, Yahya, Sousa, Ana E, Delputte, Peter, Müller-Trutwin, Michaela, Valledor, Annabel F   +15 more
openaire   +6 more sources

Connections between Metabolism and Epigenetic Modification in MDSCs [PDF]

International Journal of Molecular Sciences, 2020
Myeloid-derived suppressor cells (MDSCs) are major immunosuppressive cells in the tumor microenvironment (TME). During the differentiation and development of MDSCs from myeloid progenitor cells, their functions are also affected by a series of regulatory factors in the TME, such as metabolic reprogramming, epigenetic modification, and cell signaling ...
Haiyan Dai, Huaxi Xu, Shengjun Wang, Jie Ma   +3 more
openaire   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source