PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu +11 more
wiley +1 more source
Deletion of the scavenger receptor Scarb1 in osteoblast progenitors and myeloid cells does not affect bone mass. [PDF]
Palmieri M +6 more
europepmc +1 more source
Histone deacetylase inhibitors sensitize glioblastoma models to temozolomide and reprogram immunosuppressive myeloid cells. [PDF]
Tehrani GA +3 more
europepmc +1 more source
Rational therapeutic targeting of myeloid cells in glioblastoma: challenges and perspectives. [PDF]
Akay F, Saleh M.
europepmc +1 more source
IFNβ-pSTAT1-IRF1 axis controls colorectal tumor development through induction of immunogenic Ly6C<sup>+</sup>myeloid cells. [PDF]
Li Y +9 more
europepmc +1 more source
Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects. [PDF]
Wang Y +5 more
europepmc +1 more source
IL-6 Induces CD45 Expression on Myeloid Cells. [PDF]
Al Barashdi MA +3 more
europepmc +1 more source
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Granulocytes and monocytes, collectively called myeloid cells, are differentiated descendants from common progenitors derived from hematopoietic stem cells in the bone marrow. Commitment to either lineage of myeloid cells is controlled by distinct transcription factors followed by terminal differentiation in response to specific colony-stimulating ...
Hiroshi, Kawamoto, Nagahiro, Minato
openaire +3 more sources
Abstract There is considerable but as yet incomplete evidence for two developmental lineages of dendritic cells: a myeloid lineage shared with phagocytes and a lymphoid lineage shared with T cells. The two corresponding functional states, which may not require the existence of two formal lineages, are that myeloid dendritic cells capture
R M, Steinman, K, Inaba
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Biphenotypic (Mixed Myeloid/T-Cell) Extramedullar Myeloid Cell Tumor
Leukemia & Lymphoma, 1999A 32-year-old male with a 4-year history of chronic myelogenous leukemia (CML) in chronic phase for 4 years, then myeloid blast crisis for 7 months, developed diffuse bulky lymphadenopathy in association with a white blood count (WBC) of 17,100/mm3 with 70% blasts.
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