Results 201 to 210 of about 6,004,355 (246)

tRNA‐Derived Small RNAs in Digestive Cancers: From Translational Regulation to Immune and Extracellular Communication

Cancer Science, EarlyView.
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley   +1 more source

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review). [PDF]

Int J Mol Med
Chen Z, Wu J, Liu W, Tan J, Peng X, Zhang Y, Liang G.   +6 more
europepmc   +1 more source

Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro. [PDF]

J Neuroinflammation, 2015
Minter MR, Main BS, Brody KM, Zhang M, Taylor JM, Crack PJ.   +5 more
europepmc   +1 more source

Pure erythroid leukaemia in early infancy: Diagnostic pitfalls and clinical challenges

British Journal of Haematology, EarlyView.
Riccardo De Carli, Baptiste Le Calvez, Elodie Lainey, Catherine Settegrana, Marion Strullu, Marlene Pouthier   +5 more
wiley   +1 more source

Lung Cancer Brain Metastasis: Brain Microenvironmental Adaptation, Therapeutic Resistance and Translational Strategies

Cancer Science, EarlyView.
Lung cancer brain metastasis is shaped by dynamic crosstalk among tumor cells, the blood–brain barrier, glial and immune cells, neurons, and metabolic niches. This review integrates these mechanisms with therapeutic resistance, translational models, CNS delivery, and multidisciplinary treatment strategies.
Jun Yang, Junyi Xiong, Li Ying, Yanyang Zeng, Ziqiang Ouyang, Mei Liu, Meihua Li   +6 more
wiley   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

Cell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo, Xiaoya Zhang, Danmei Zhang, Chunxia Shi, Luwen Wang, Zuojiong Gong   +5 more
wiley   +1 more source

<i>Additional sex combs-like 1</i> variants in an acute myeloid leukaemia and a general elderly cohort in central South Africa. [PDF]

Afr J Lab Med
Bergman MV, Kloppers JF, Bester PA, van Marle AC.   +3 more
europepmc   +1 more source

Solitary Indeterminate Cell Histiocytosis Presenting as a Reddish Nodule on the Abdomen of a 4‐Year‐Old Boy: Clinicopathologic Correlation and Electron Microscopy Findings

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Indeterminate cell histiocytosis (ICH) is a clonal proliferative disorder of mononuclear phagocyte cells that shows features of both dendritic and histiocytic cells. Only around 100 cases of ICH were reported, and among them, only 24% of reported cases involve pediatric patients, with a mean age at diagnosis of 50 years.
Seung‐Soo Lee, Seok‐Jong Lee, Weon Ju Lee, Dae‐Lyong Ha   +3 more
wiley   +1 more source

Pediatric Acute Leukemias: Epidemiological, Clinical Features, and Diagnostic Contribution of Flow Cytometry in a Resource-Limited Setting. [PDF]

Cureus
Regragui I, Mamad H, Zirar J, Sbay Y, Ifleh M, Benkirane S, Masrar A.   +6 more
europepmc   +1 more source