Results 1 to 10 of about 17,238,583 (283)
Clinical validation of nuclear factor kappa B expression in invasive breast cancer
Tumor Biology, 2018 Breast cancer is the most commonly diagnosed cancer in Polish women. The expression of transcription nuclear factor kappa B, a key inducer of inflammatory response promoting carcinogenesis and cancer progression in breast cancer, is not well-established.
Anil Kumar Agrawal +5 more
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Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis [PDF]
Endocrinology and Metabolism, 2023 Maintenance of skeletal integrity requires the coordinated activity of multinucleated bone-resorbing osteoclasts and bone-forming osteoblasts. Osteoclasts form resorption lacunae on bone surfaces in response to cytokines by fusion of precursor cells ...
Brendan F. Boyce +3 more
doaj +3 more sources
Neuroinflammation in schizophrenia: the role of nuclear factor kappa B [PDF]
Translational Psychiatry, 2021 Neuroinflammation, particularly in the dorsolateral prefrontal cortex, is well-established in a subset of people with schizophrenia, with significant increases in inflammatory markers including several cytokines. Yet the cause(s) of cortical inflammation
Caitlin E. Murphy +2 more
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Targeting Nuclear Factor-kappa B to overcome resistance to chemotherapy. [PDF]
Frontiers in Oncology, 2013 Intrinsic or acquired resistance to chemotherapeutic agents is a common phenomenon and a major challenge to the treatment of cancer patients, especially those with progressive disease.
Peter eGodwin +5 more
doaj +5 more sources
Frontiers in Cell and Developmental Biology, 2022 Endocrine and metabolic diseases show increasing incidence and high treatment costs worldwide. Due to the complexity of their etiology and mechanism, therapeutic strategies are still lacking.
Luodan Zhang +5 more
doaj +3 more sources
Nuclear factor kappa-B and histopathology of chronic gastritis
Indian Journal of Pathology and Microbiology, 2010 Background: Studies suggest that nuclear factor kappa-B (NFκB) activation may be a critical event in the production of proinflammatory molecules in Helicobacter pylori-associated gastritis.
Moorchung Nikhil +4 more
doaj +3 more sources
A study of nuclear transcription factor-kappa B in childhood autism. [PDF]
PLoS ONE, 2011 BACKGROUND: Several children with autism show regression in language and social development while maintaining normal motor milestones. A clear period of normal development followed by regression and subsequent improvement with treatment, suggests a ...
Usha S Naik +5 more
doaj +4 more sources
Nuclear factor-kappa B and diabetic nephropathy
Linchuang shenzangbing zazhi, 2019 Diabetes is a metabolic disease that affects most of the world’s population. Diabetic nephropathy(DN) is the main complication of diabetes mellitus and the main cause of end-stage renal diseases.
TAN Xiao-yan +2 more
doaj +1 more source
Nuclear factor kappa B—molecular biomedicine: the next generation
Biomedicine and Pharmacotherapy, 2004 Nuclear factor kappa B (NFkappaB) as a transcription factor plays an important integrating role in the intracellular regulation of immune response, inflammation and cell cycle regulation. Nouvelle insights into the structure and regulation of activation of NFkappaB have brought a detailed picture of the function of this transcription factor.
Peter Celec
exaly +3 more sources
Nuclear Factor-Kappa B-induced miRNA-518a-5p represses trophoblast cell migration and invasion by the Nuclear Factor-Kappa B pathway [PDF]
Anais da Academia Brasileira de Ciências, 2023 Preeclampsia is associated with the insufficient invasion of trophoblasts. NF-κB is a transcription factor in almost all mammalian cells and has been validated to be upregulated in the maternal circulation and placenta of women with preeclampsia.
XING PENG +3 more
doaj +1 more source