Results 21 to 30 of about 17,238,583 (283)
Heliyon, 2022 Context: Torin2 has various pharmacological properties. However, its anti-inflammatory activity has not been reported. Objective: This study focused on the potential anti-inflammatory properties of Torin2 in lipopolysaccharide (LPS)-evoked RAW264.7 ...
Shanshan Wei +5 more
doaj +1 more source
Endurance exercise training suppresses myostatin upregulation and nuclear factor-kappa B activation in a mouse model of Parkinson's disease [PDF]
Veterinary World, 2022 Background and Aim: Muscle atrophy is common in Parkinson's disease (PD). Although myostatin has been implicated in muscle atrophy, its expression in PD skeletal muscle has not been investigated.
Nour S. Erekat, Muhammed D. Al-Jarrah
doaj +1 more source
Nuclear factor-kappa B pathways in Drosophila [PDF]
Oncogene, 2006 The nuclear factor kappa B (NF-kappaB) pathways in Drosophila are multi-component pathways, as in vertebrates, that regulate the expression of many genes responsible for the formation of dorsal-ventral polarity in the early embryo, the innate immune response to infection with Gram- negative and positive bacteria and fungi, the cellular immune response ...
S, Minakhina, R, Steward
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Exploring new pathways in endocrine-resistant breast cancer
Exploration of Targeted Anti-tumor Therapy, 2022 The most common breast cancer (BC) subtypes are hormone-dependent, being either estrogen receptor-positive (ER+), progesterone receptor-positive (PR+), or both, and altogether comprise the luminal subtype.
Inês Soares de Pinho +6 more
doaj +1 more source
The Effect of Open Reading Frame 3 of Hepatitis E virus on Cellular NF-κB Activity [PDF]
Basrah Journal of Veterinary Research, 2023 NF-B (Nuclear Factor Kappa B) is a crucial transcription factor that is essential for host survival during pathogen infection in animal and human. Therefore, it has been a main goal for numerous pathogens to modify cellular NF-κB activity to create
Rana Abdulnabi +2 more
doaj +1 more source
MicroRNA Roles in the Nuclear Factor Kappa B Signaling Pathway in Cancer
Frontiers in Immunology, 2018 Nuclear factor kappa B (NF-κB) is a pluripotent and crucial dimer transcription factor that orchestrates various physiological and pathological processes, especially cell proliferation, inflammation, and cancer development and progression.
Jin’en Wu +5 more
doaj +1 more source
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma [PDF]
, 2009 Proliferation and survival of Hodgkin and Reed/Sternberg (HRS) cells, the malignant cells of classical Hodgkin lymphoma (cHL), are dependent on constitutive activation of nuclear factor {kappa}B (NF-{kappa}B).
Inga Vater +25 more
core +1 more source
The role of NF-kB in the mechanisms of inflammation of the stomach’s mucosa in children
Сучасна педіатрія: Україна, 2023 Introduction. One of the important and unresolved issues of pediatric gastroenterology remains study of inflammation mechanisms of the stomach’s mucosa, as well as factors that regulate inflammatory reactions.
V.І. Bobrova
doaj +1 more source
The role of nuclear factor kappa B in human labour [PDF]
Reproduction, 2005 Abstract Preterm birth remains the leading cause of perinatal mortality and morbidity, largely as a result of a poor understanding of the precise mechanisms controlling labour onset in humans. Inflammation has long been recognised as a key feature of both preterm and term labour, with an influx of inflammatory cells into the uterus ...
Tamsin M, Lindström, Phillip R, Bennett
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Nuclear Factor Kappa B Signaling Complexes in Acute Inflammation [PDF]
Antioxidants & Redox Signaling, 2020 Significance: Nuclear factor kappa B (NF-κB) is a master regulator of the inflammatory response and represents a key regulatory node in the complex inflammatory signaling network. In addition, selective NF-κB transcriptional activity on specific target genes occurs through the control of redox-sensitive NF-κB interactions.
Rius-Pérez, Sergio +4 more
openaire +4 more sources