Results 11 to 20 of about 17,238,583 (283)

Immunomodulatory effects of curcumin on receptor activator of nuclear factor-kappa B ligand in periodontitis [PDF]

open access: yesMediterranean Journal of Pharmacy and Pharmaceutical Sciences
Periodontitis is a chronic inflammatory disease of the tooth-supporting structures, often causing alveolar bone loss due to increased osteoclast activity mediated by receptor activator of nuclear factor-kappa B ligand.
Fiki Muhammad Ridho
doaj   +6 more sources

How to Inhibit Nuclear Factor-Kappa B Signaling: Lessons from Poxviruses

open access: yesPathogens, 2022
The Nuclear Factor-kappa B (NF-κB) family of transcription factors regulates key host inflammatory and antiviral gene expression programs, and thus, is often activated during viral infection through the action of pattern-recognition receptors and ...
Joshua B. Reus   +2 more
doaj   +2 more sources

Nuclear factor kappa-B and the heart [PDF]

open access: yesJournal of the American College of Cardiology, 2001
Nuclear factor kappa-B (NFkappaB), a redox-sensitive transcription factor regulating a battery of inflammatory genes, has been indicated to play a role in the development of numerous pathological states. Activation of NFkappaB induces gene programs leading to transcription of factors that promote inflammation, such as leukocyte adhesion molecules ...
Valen, Guro   +2 more
openaire   +3 more sources

Tumour Necrosis Factor-alpha and Nuclear Factor-kappa B Gene Variants in Sepsis

open access: yesBalkan Medical Journal, 2018
Background: The humoral system is activated and various cytokines are released due to infections in tissues and traumatic damage. Nuclear factor-kappa B dimers are encoded by nuclear factor-kappa B genes and regulate transcription of several crucial ...
Leyla Acar   +3 more
doaj   +2 more sources

NLRP12 Alleviated Periodontal Destruction via Suppressing Nuclear Factor Kappa-B Signalling Pathway [PDF]

open access: yesInternational Dental Journal
Objective: Periodontal ligament stem cells (PDLSCs) have been shown to demonstrate robust tissue regeneration capabilities. NACHT, leucine-rich repeat and PYD-containing 12 (NLRP12) could exerts negative inflammatory regulatory role in various ...
Shuangshuang Xu   +5 more
doaj   +2 more sources

Organelle symphony: Nuclear factor erythroid 2-related factor 2 and nuclear factor-kappa B in stroke pathobiology [PDF]

open access: yesNeural Regeneration Research
Strokes include both ischemic stroke, which is mediated by a blockade or reduction in the blood supply to the brain, and hemorrhagic stroke, which comprises intracerebral hemorrhage and subarachnoid hemorrhage and is characterized by bleeding within the ...
Ziliang Hu   +6 more
doaj   +2 more sources

Cysteine-rich zinc finger proteins and the nuclear factor kappa-B pathway [PDF]

open access: yesFrontiers in Chemical Biology
Inflammation-related disorders, such as autoimmune diseases and cancer, impose a significant global health burden. Zinc finger proteins (ZFs) are ubiquitous metalloproteins which regulate inflammation and many biological signaling pathways related to ...
Andrew T. Stoltzfus, Sarah L. J. Michel
doaj   +2 more sources

NF-κB "decoy" inhibits COX-2 expression in epileptic rat brain [PDF]

open access: yesJournal of Integrative Neuroscience, 2020
There is a need to investigate the role of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression in the epileptic rat brain and cultured hippocampal neurons.
Jing Xu, Yiping Sun, Yongshun Zhao, Qifa Li, Biying Ge, Shufang Dai, Kemin Liu, Hong Xu, Lei Fu, Jie Zhao
doaj   +1 more source

Nuclear Factor Kappa B Pathway and human cancer therapeutics [PDF]

open access: yes, 2009
A thesis submitted in partial fufilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyCancer is one of the major causes of morbidity in the world.
Guo, Xiaoxia
core   +3 more sources

Effect of NF-κB-related microRNA in multiple myeloma [PDF]

open access: yesXin yixue, 2022
The incidence of multiple myeloma (MM) has been increasing year by year, which is one of the common tumors in the blood system. At present, MM is still an incurable disease. MM recurrence and drug resistance are urgently to be resolved.
Chen Wenxian, Liu Jiaqin, Yang Hang, Zhou Lixi
doaj   +1 more source

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