Predictive value of hematological and phenotypical parameters on postchemotherapy leukocyte recovery [PDF]
, 2009 Background: Grade IV chemotherapy toxicity is defined as absolute neutrophil count <500/μL. The nadir is considered as the lowest neutrophil number following chemotherapy, and generally is not expected before the 7th day from the start of chemotherapy.
Abbasciano V +15 more
core +1 more source
Myeloperoxidase as an Active Disease Biomarker: Recent Biochemical and Pathological Perspectives
Medical Science, 2018 Myeloperoxidase (MPO) belongs to the family of heme-containing peroxidases, produced mostly from polymorphonuclear neutrophils. The active enzyme (150 kDa) is the product of the MPO gene located on long arm of chromosome 17.
A. Khan, M. Alsahli, A. Rahmani
semanticscholar +1 more source
Functional maturation during bovine granulopoiesis [PDF]
, 2002 Granulocytic precursor cells undergo morphologic changes in the nucleus and the cytoplasm during the process of granulopoiesis, which takes place in the bone marrow.
Burvenich, Christian +2 more
core +2 more sources
Frontiers in Oncology, 2022 BackgroundMyeloperoxidase (MPO) has been demonstrated to be a local mediator of inflammation in tissue damage in various inflammatory diseases. Given its controversial effect on colorectal cancer (CRC), there has been growing interest in investigating ...
Meilin Weng +19 more
doaj +1 more source
Inflammation, DNA-centered radicals, and oxidative genotoxicity: The role of HOCl produced by myeloperoxidase in carcinogenesis [PDF]
, 2009 Myeloid cells (macrophages and neutrophils) infiltrate and synthesize myeloperoxidase (MPO) in sites of inflammation, producing gentotoxicity. In RAW 264.7 macrophages, bacterial lipopolysaccharide (LPS) induces superoxide radical anion, nuclear ...
Dario C. Ramirez +2 more
core +2 more sources
Gut Microbes, 2021 Recent studies have gained a better appreciation of the potential impacts of enteric infections beyond symptomatic diarrhea. It is recognized that infections by several enteropathogens could be associated with growth deficits in children and intestinal ...
Jessica Brubaker +5 more
doaj +1 more source
Reply to "Unrealistic nonphysiological amounts of reagents and a disregard for published literature" [PDF]
, 2015 Peer reviewedPublisher ...
Brown, Alistair J P
core +2 more sources
In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury [PDF]
, 2006 Background: Intravenous salbutamol (albuterol) reduces lung water in patients with the acute respiratory distress syndrome (ARDS). Experimental data show that it also reduces pulmonary neutrophil accumulation or activation and inflammation in ARDS ...
McAuley, Daniel F. +4 more
core +2 more sources
The Roles of Neutrophil-Derived Myeloperoxidase (MPO) in Diseases: The New Progress
AntioxidantsMyeloperoxidase (MPO) is a heme-containing peroxidase, mainly expressed in neutrophils and, to a lesser extent, in monocytes. MPO is known to have a broad bactericidal ability via catalyzing the reaction of Cl− with H2O2 to produce a strong oxidant ...
Wei Lin +3 more
semanticscholar +1 more source
Degradation of Single-Layer and Few-Layer Graphene by Neutrophil Myeloperoxidase.
Angewandte Chemie, 2018 Biodegradability of graphene is one of the fundamental parameters determining the fate of this material in vivo. Two types of aqueous dispersible graphene, corresponding to single-layer (SLG) and few-layer graphene (FLG), devoid of either chemical ...
Rajendra Kurapati +7 more
semanticscholar +1 more source