Results 71 to 80 of about 60,147 (299)

Putative Astroglial Dysfunction in Schizophrenia: A Meta-Analysis of 1H-MRS Studies of Medial Prefrontal Myo-Inositol

Frontiers in Psychiatry, 2018
Background: Several lines of evidence support a role for astroglial pathology in schizophrenia. Myo-inositol is particularly abundant in astroglia. Many small sized studies have reported on myo-inositol concentration in schizophrenia, but to date these ...
Tushar Kanti Das, Tushar Kanti Das, Tushar Kanti Das, Avyarthana Dey, Avyarthana Dey, Priyadharshini Sabesan, Alborz Javadzadeh, Jean Théberge, Jean Théberge, Joaquim Radua, Lena Palaniyappan, Lena Palaniyappan, Lena Palaniyappan, Lena Palaniyappan   +13 more
doaj   +1 more source

The Calbindin-D28k binding site on inositol monophosphatase may allow inhibition independent of the lithium site of action [PDF]

, 2011
Among numerous reported biochemical effects the lithium-inhibitable enzyme inositol-monophosphatase (IMPase) remains a viable target for lithium's therapeutic mechanism of action.
Amnon Hoffman, Chaim Gilon, Galila Agam, Itshak Levi, Joseph Fanous, Miriam Eisenstein, Orna Almog, Yael Askira, Yftah Talgan   +8 more
core   +1 more source

Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers. [PDF]

, 2019
Background and purposeThe objective of this study was to longitudinally investigate the trajectory of change in 1 H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow-up, and to determine the time at which the ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill, Gunter, Jeffrey L, Haley, Dana, Jones, David, Kantarci, Kejal, Knopman, David, Kraft, Ruth, Lapid, Maria, Lesnick, Timothy, Rademakers, Rosa, Rosen, Howie, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +22 more
core   +3 more sources

Myo‐Inositol Mitigates Oxidative Stress in Bovine Mammary Epithelial Cells via Activation of the SIRT5/Nrf2 Signaling Axis

Animal Research and One Health, EarlyView.
Myo‐inositol alleviates oxidative stress in dairy cow mammary epithelial cells via the Sirt5/Nrf2 pathway to promote mitochondrial fusion. This graphical abstract was created with BioRender.com. ABSTRACT High‐yielding dairy cows are susceptible to mammary gland oxidative stress due to prolonged intensive lactation, leading to redox imbalance.
Yufei Zhang, Yu Cao, Meng Zhang, Huijie Hu, He Ma, Junlong Bi, Juxiong Liu, Shoupeng Fu, Wenjin Guo   +8 more
wiley   +1 more source

Mandibular Endochondral Growth Is Specifically Augmented by Nutritional Supplementation with Myo-Inositol Even in Rabbits

Dentistry Journal
Mandibular retrognathism occurs by insufficient mandibular growth and causes several issues, such as respiratory difficulty and diminished masticatory function.
Miho Shimoyama, Hiroyuki Kanzaki, Syunnosuke Tohyama, Tomomi Ida, Misao Ishikawa, Yuta Katsumata, Chihiro Arai, Satoshi Wada, Shugo Manase, Hiroshi Tomonari   +9 more
doaj   +1 more source

A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease

Microbial Cell Factories, 2011
Background A stereoisomer of inositol, scyllo-inositol, is known as a promising therapeutic agent for Alzheimer's disease, since it prevents the accumulation of beta-amyloid deposits, a hallmark of the disease.
Takenaka Shinji, Morinaga Tetsuro, Osawa Shin, Yamaoka Masaru, Yoshida Ken-ichi   +4 more
doaj   +1 more source

Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection [PDF]

, 2018
This work was supported by the National Institutes of Health (R01AI080275 and R21AI22352), the NIH Fogarty International Center (R25TW009345), the University of Minnesota Center for Translational Science Institute (UL1TR000114), Wellcome Trust (086827 ...
Gow, Neil A R, Lee, Keunsook, Mukaremera, Liliane, Nielsen, Kirsten, Wagener, Jeanette, Wiesner, D. L.   +5 more
core   +1 more source

Structural and Functional Properties of Ingredient Composition in Kenkey Preparation: A Review

ChemFoodChem, EarlyView.
This review synthesizes three decades of research on kenkey, a fermented maize staple of West Africa. Examining the structural, functional, and nutritional properties that emerge from traditional fermentation and thermal processing, and identifying priorities for future research toward quality standardization and commercial development. ABSTRACT Kenkey,
Afia Sakyiwaa Amponsah
wiley   +1 more source

Enzymatic assay of myo-inositol in serum [PDF]

Fresenius' Zeitschrift für analytische Chemie, 1986
An enzymatic spectrophotometric method for determination of myo-inositol in serum is described. The method is sensitive and rapid to perform without special equipment. Linearity between the amount of myo-inositol and absorbance was obtained in the range of 0.5 to 3 nmol myo-inositol per assay.
Dolhofer, Roswitha, WIELAND, O.
openaire   +3 more sources

Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews [PDF]

, 2018
Background Successful treatments for gestational diabetes mellitus (GDM) have the potential to improve health outcomes for women with GDM and their babies. Objectives To provide a comprehensive synthesis of evidence from Cochrane systematic reviews of
Alsweiler, Jane, Brown, Julie, Crowther, Caroline A, Downie, Michelle R, Martis, Ruth, Shepherd, Emily   +5 more
core   +1 more source