Results 91 to 100 of about 61,720 (280)

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

open access: yesCell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge   +8 more
wiley   +1 more source

Hypotonic activation of the myo-inositol transporter SLC5A3 in HEK293 cells probed by cell volumetry, confocal and super-resolution microscopy.

open access: yesPLoS ONE, 2015
Swelling-activated pathways for myo-inositol, one of the most abundant organic osmolytes in mammalian cells, have not yet been identified. The present study explores the SLC5A3 protein as a possible transporter of myo-inositol in hyponically swollen ...
Joseph Andronic   +7 more
doaj   +1 more source

Versatile synthesis of myo-inositol phospholipid precursors

open access: yes, 1997
Homochiral myo-inositol derivatives 16 and 20 and their corresponding enantiomers possessing either the natural or unnatural ring stereochemistry for inositol phospholipids are synthesised from myo-inositol derivatives 8 and 9 respectively using camphor ...
Gilbert, Ian H.   +4 more
core   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

open access: yesThe FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia   +7 more
wiley   +1 more source

Regulatory mechanism of exogenous myo-inositol improving high temperature stress tolerance of tomato seedlings

open access: yesXibei zhiwu xuebao
[Objective] Studing the effect of exogenous myo-inositol on the physiological and biochemical indexes of tomato seedlings and the molecular mechanism of tolerance to high temperature stress will provide a theoretical basis for the improvement of heat ...
CHEN Yan   +5 more
doaj   +1 more source

The Free Myo-Inositol of Thyroid Tissue.

open access: yesExperimental Biology and Medicine, 1959
SummaryBioassay with Kloeckera Brevis yeast has been employed to measure content of free myo-inositol in human, rat, rabbit, sheep and guinea pig thyroid glands. In all species, thyroid/plasma concentration differentials for free myo-inositol were greater than 100.
N, FREINKEL   +3 more
openaire   +2 more sources

Discovery of a Catalytic Asymmetric Phosphorylation through Selection of a Minimal Kinase Mimic:  A Concise Total Synthesis of d-myo-Inositol-1-Phosphate

open access: yes, 2016
Discovery of a Catalytic Asymmetric Phosphorylation through Selection of a Minimal Kinase Mimic:  A Concise Total Synthesis of d-myo-Inositol-1 ...
Bianca R. Sculimbrene (2204239)   +1 more
core   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

open access: yesThe FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs   +9 more
wiley   +1 more source

AzioInositols in the Treatment of Insulin-Mediated Diseases

open access: yesInternational Journal of Endocrinology, 2016
A growing body of research is currently focused on the role of inositol isomers and in particular myo-inositol (MYO-INS) and D-chiroinositol (DCI) in the treatment of insulin resistance states. Both isomers have been shown to exert insulin-mimetic action
Giovanna Muscogiuri   +3 more
doaj   +1 more source

Inositol phosphates in the environment

open access: yes, 2002
The inositol phosphates are a group of organic phosphorus compounds found widely in the natural environment, but that represent the greatest gap in our understanding of the global phosphorus cycle.
Ian D. Mckelvie   +7 more
core   +1 more source

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