Results 91 to 100 of about 28,872 (211)

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt   +16 more
wiley   +1 more source

Challenges and Future Directives of Synthetic Biology in Engineering Plant–Microbe Partnerships for Sustainable Agriculture

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 10, Page 2491-2519, October 2026.
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma   +6 more
wiley   +1 more source

Integrated Metabolomic and Bioenergetic Profiling Reveals Axl as a Key Regulator of Macrophage Homeostasis

open access: yesEuropean Journal of Immunology, Volume 56, Issue 10, October 2026.
Axl deficiency disrupts peritoneal macrophage identity and function, impairing glycolysis, TCA metabolism, and mitochondrial respiration while weakening antioxidant defenses. This coordinated metabolic and redox collapse extends systemically, highlighting Axl as a key regulator of immunometabolic homeostasis.
Jesuino R M Ferreira   +15 more
wiley   +1 more source

Myo-inositol affects the health, metabolome, and lactation performance of peripartum dairy cows

open access: yesFrontiers in Immunology
IntroductionYeast culture (YC) has become a crucial microecological preparation for regulating the ruminal environment and improving ruminant health. Myo-inositol is an effective substance in YC, our study aimed to investigate whether myo-inositol can ...
Chun-zheng Wang   +23 more
doaj   +1 more source

Potentially Toxic Elements and Male Reproductive Toxicity: Mechanisms, Implications, and Protective Strategies: A Narrative Review

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Potentially toxic elements impair male reproductive function through oxidative stress, DNA damage, mitochondrial dysfunction, inflammation, endocrine disruption and epigenetic alterations. Antioxidants, phytochemicals, chelating agents and healthy lifestyle interventions may help mitigate testicular toxicity and preserve fertility.
Sakshi Yadav, Placheril J John
wiley   +1 more source

Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Urolithin A (UA) and urolithin B (UB) are gut microbiota‐derived metabolites of ellagitannins reported to influence mitochondrial function, inflammation and muscle metabolism. Their comparative transcriptomic effects in human skeletal muscle cells remain undefined.
Yves Henrotin   +8 more
wiley   +1 more source

Nitrogen Fertilization Temporarily Enhances Phosphatase Activity in a High‐P Loamy Sand

open access: yesJournal of Plant Nutrition and Soil Science, Volume 189, Issue 5, Page 794-802, October 2026.
ABSTRACT Background Efficient plant utilization of soil phosphorus (P) is essential to reduce dependence on mineral P fertilizers in intensive agriculture. Input of mineral nitrogen (N) fertilizers and its chemical form may influence the activity of P mineralizing enzymes, but how this interaction operates under field conditions in a soil with high P ...
Ingeborg F. Pedersen   +3 more
wiley   +1 more source

Short Echo‐Time Spiral MRSI Versus Single‐Voxel Spectroscopy in the Human Brain at 3 Tesla With Semi‐LASER Localization

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1524-1533, October 2026.
ABSTRACT Purpose Magnetic resonance spectroscopy techniques are widely used to non‐invasively study brain metabolism. Despite advances in magnetic resonance spectroscopic imaging (MRSI), there is a notable absence of research on comparing fast non‐Cartesian MRSI with single‐voxel spectroscopy (SVS), limiting our understanding of its performance and ...
Young Woo Park   +3 more
wiley   +1 more source

1H HR‐MAS NMR Metabolomics in Combination With Transcriptomic Correlation Provides New Insights Into Metabolic Heterogeneity Across Breast Cancer Immunohistochemical Subtypes

open access: yesNMR in Biomedicine, Volume 39, Issue 10, October 2026.
Metabolomic profiling of breast cancer tissue using 1H HR‐MAS NMR spectroscopy and LCModel‐based quantitative analysis revealed metabolite differences associated with immunohistochemical subtypes, and subsequent metabolomics–transcriptomics integration linked these subtype‐dependent metabolic signatures to pathways in choline metabolism, one‐carbon ...
Irene Garcia‐Bocanegra   +10 more
wiley   +1 more source

A 58‐year‐old woman experiencing occasional dizziness, impaired awareness, and deep feeling of fear

open access: yes
Brain Pathology, Volume 36, Issue 6, November 2026.
Alessandro Selvaggini   +5 more
wiley   +1 more source

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