Results 81 to 90 of about 61,720 (280)

Effects of different supplements on Hashimoto’s thyroiditis: a systematic review and network meta-analysis

Frontiers in Endocrinology
Clinicians often consider the use of dietary supplements to assist in lowering thyroid autoantibody titres in patients with Hashimoto’s thyroiditis (HT). Currently, different supplements differ in their ability to reduce autoantibody levels.
Bingcong Peng, Weiwei Wang, Qingling Gu, Ping Wang, Weiping Teng, Zhongyan Shan   +5 more
doaj   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source

Antioxidant and anticoagulant properties of myo-inositol determined in an ex vivo studies and gas chromatography analysis

Scientific Reports
Myo-inositol plays a key role in the vasculature and may be beneficial for preventing harmful environmental effects. In this study aortic rings were isolated from middle-aged (12-month-old) male Wistar rats and preincubated with myo-inositol (0.01–100 mg/
Agata Rolnik, Beata Olas, Joanna Szablińska-Piernik, Lesław Bernard Lahuta, Leszek Gromadziński, Michał S. Majewski   +5 more
doaj   +1 more source

The effect of Myo-inositol on sperm parameters and pregnancy rate in oligoasthenospermic men treated with IUI: A randomized clinical trial

International Journal of Reproductive BioMedicine, 2019
Background In about 40% of the couples, the cause of infertility problems is attributed to men because of low sperm production and disturbed motility of sperm.
Afsane Ghasemi, Fatemehsadat Amjadi, Seyedeh Masoumeh Ghazi Mirsaeed, Robabeh Mohammad Beigi, Samaneh Ghasemi, Yousef Moradi, Seyedeh Tahereh Ghazi Mirsaeed   +6 more
doaj   +1 more source

Myo-inositol in autoimmune thyroiditis, and hypothyroidism

Reviews in Endocrine and Metabolic Disorders, 2018
Myo-inositol (Myo-Ins) plays an important role in thyroid function and autoimmunity. Myo-Ins is the precursor for the synthesis of phosphoinositides, which takes part in the phosphatidylinositol (PtdIns) signal transduction pathway, and plays a decisive role in several cellular processes.
Fallahi, Poupak, Ferrari, Silvia Martina, Elia, Giusy, Ragusa, Francesca, Paparo, Sabrina Rosaria, Caruso, Claudia, Guglielmi, Giovanni, Antonelli, Alessandro   +7 more
openaire   +3 more sources

(+/-)-1,2 : 5,6-di-O-isopropylidene-myo-inositol and (+/-)-6-O-benzoyl-1,2 : 4,5-di-O- isopropylidene-myo-inositol: a practical preparation of key intermediates for myo-inositol phosphates

, 2019
A simple and practical synthetic procedure for the versatile intermediates, (+/-)-1,2:5,6-di-O-isopropylidene-myo-inositol and (+/-)-6-O-benzoyl-1,2:4,5-di-O-isopropylidene-myo-inositol, is described. (C) 2002 Elsevier Science Ltd.
Chang, Young-Tae, Khersonsky, SM
core   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Comparison of Efficacy between Myo-Inositol versus Metformin in Women with Polycystic Ovary Syndrome

Life and Science
Objective: To compare the effectiveness of myo-inositol versus metformin in treating women with polycystic ovary syndrome. Study Design: Cross-sectional study. Place and Duration of Study: The study was carried out at the Department of Gynae Unit II, Dr.
Nurmeen Latif, Seema Rajar, Mehreen Yousuf, Sadaf Imtiaz, Sidrah Abbas, Zara Jamali   +5 more
doaj   +1 more source

The Calbindin-D28k binding site on inositol monophosphatase may allow inhibition independent of the lithium site of action

, 2011
Among numerous reported biochemical effects the lithium-inhibitable enzyme inositol-monophosphatase (IMPase) remains a viable target for lithium's therapeutic mechanism of action.
Galila Agam, Itshak Levi, Orna Almog, Miriam Eisenstein, Joseph Fanous, Yael Askira, Amnon Hoffman, Yftah Talgan, Chaim Gilon   +8 more
core  

Metabolic Phenotype Predicts Biochemical Response to Inositol Supplementation in Polycystic Ovary Syndrome: A Systematic Review and Meta‐Analysis

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To evaluate the effect of inositol supplementation on biochemical hyperandrogenism in women with polycystic ovary syndrome (PCOS) and to explore whether metabolic phenotype modifies the endocrine response. Design Systematic review and meta‐analysis of randomized controlled trials conducted in accordance with PRISMA guidelines ...
Daniele Tienforti, Gennaro Puocci, Claudia Venditti, Valentina Gizzi, Carlo Pisanò, Elisa Cocci, Elisabetta Perfetto, Francesco D'Alessandro, Luca Spagnolo, Marco Giorgio Baroni, Arcangelo Barbonetti   +10 more
wiley   +1 more source