Results 101 to 110 of about 27,570 (221)

Myo-inositol: with or without.

Endocrine journal, 2015
Carlomagno, G, Unfer, V, BENVENGA, Salvatore, Nestler, Je   +3 more
openaire   +2 more sources

Effect of Water Suppression and Metabolite Cycling on Quantification of 1H MRS Spectra in the Human Brain at 3 Tesla

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 542-547, August 2026.
ABSTRACT Purpose This study investigates the effect of VAPOR water suppression and metabolite cycling on metabolite quantification and macromolecules in proton magnetic resonance spectroscopy. Methods Single‐voxel semi‐LASER spectra (TR/TE = 3000/28 ms) and metabolite‐nulled spectra (macromolecules) were acquired in five healthy subjects in the ...
Dinesh K. Deelchand, Pierre‐Gilles Henry   +1 more
wiley   +1 more source

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 557-567, August 2026.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon, Meng Gu, Ralph Hurd, Kirk Riemer, Frank Hanley, Daniel Spielman   +5 more
wiley   +1 more source

The Impact and Reliability of Tissue Segmentation on In Vivo Magnetic Resonance Spectroscopy Metabolite Quantification

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 516-529, August 2026.
ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald, Kay Chioma Igwe, Antonia Kaiser, Karl Landheer, Jaimie Lee, John L. K. Kramer, Aaron T. Gudmundson, Helge J. Zöllner, Georg Oeltzschner, Candace C. Fleischer, Niklaus Zölch, Jamie Near, Mark Mikkelsen   +12 more
wiley   +1 more source

MR Spectroscopy Without Water Suppression Using the Gradient Impulse Response Function

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 530-541, August 2026.
ABSTRACT PurposeNon‐water‐suppressed proton spectroscopy, 1H‐MRS, is desirable, as retaining the strong water resonance can facilitate automated online data corrections, internal concentration referencing, and monitoring of line narrowing effects in functional MRS. Removal of the water suppression module can also mitigate magnetization transfer effects
James B. Bacon, Peter Jezzard, William T. Clarke   +2 more
wiley   +1 more source

Metabolic Assessment in Human Pluripotent Stem Cell‐Derived Cerebral Organoids Using HR‐MAS NMR Spectroscopy

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
We present a direct method for evaluating metabolism in intact hPSC‐derived cerebral organoids (COs) via HR‐MAS 1H‐NMR spectroscopy. This approach suggests that COs exhibit a metabolic profile similar to in vivo human fetal brain, with high levels of lactate and hTau, low levels of NAA, and equimolar levels of Glu and Gln.
Maria Alejandra Castilla Bolanos, Vorapin Chinchalongporn, Rajshree Ghosh Biswas, Colleen Bailey, Maggie Wu, Ronald Soong, Fermisk Saleh, Andre Simpson, Carol Schuurmans, Jamie Near   +9 more
wiley   +1 more source

THE SYNTHESIS OF myo-INOSITOL IN THE RAT

Journal of Biological Chemistry, 1955
J W, HALLIDAY, L, ANDERSON
openaire   +2 more sources

Maize Biofortification Approaches for Fighting Malnutrition in Sub‐Saharan Africa

Plant-Environment Interactions, Volume 7, Issue 4, August 2026.
ABSTRACT Maize is a staple food in sub‐Saharan Africa (SSA); however, commonly used maize varieties are deficient in essential nutrients, including lysine, tryptophan, vitamin A, and minerals such as iron (Fe) and zinc (Zn). As a result, millions of people in this region suffer from one or more nutrient deficiencies that commonly lead to malnutrition ...
Bitew Tilahun Engida, Tesfaye Walle Mekonnen, Maryke Labuschagne   +2 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, Volume 26, Issue 8, Page 9-28, August 2026.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Metabolic Phenotype Predicts Biochemical Response to Inositol Supplementation in Polycystic Ovary Syndrome: A Systematic Review and Meta‐Analysis

Clinical Endocrinology, Volume 105, Issue 2, Page 237-244, August 2026.
ABSTRACT Objective To evaluate the effect of inositol supplementation on biochemical hyperandrogenism in women with polycystic ovary syndrome (PCOS) and to explore whether metabolic phenotype modifies the endocrine response. Design Systematic review and meta‐analysis of randomized controlled trials conducted in accordance with PRISMA guidelines ...
Daniele Tienforti, Gennaro Puocci, Claudia Venditti, Valentina Gizzi, Carlo Pisanò, Elisa Cocci, Elisabetta Perfetto, Francesco D'Alessandro, Luca Spagnolo, Marco Giorgio Baroni, Arcangelo Barbonetti   +10 more
wiley   +1 more source