Results 101 to 110 of about 60,147 (299)

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon, Meng Gu, Ralph Hurd, Kirk Riemer, Frank Hanley, Daniel Spielman   +5 more
wiley   +1 more source

Antioxidant and anticoagulant properties of myo-inositol determined in an ex vivo studies and gas chromatography analysis

Scientific Reports
Myo-inositol plays a key role in the vasculature and may be beneficial for preventing harmful environmental effects. In this study aortic rings were isolated from middle-aged (12-month-old) male Wistar rats and preincubated with myo-inositol (0.01–100 mg/
Agata Rolnik, Beata Olas, Joanna Szablińska-Piernik, Lesław Bernard Lahuta, Leszek Gromadziński, Michał S. Majewski   +5 more
doaj   +1 more source

The effect of Myo-inositol on sperm parameters and pregnancy rate in oligoasthenospermic men treated with IUI: A randomized clinical trial

International Journal of Reproductive BioMedicine, 2019
Background In about 40% of the couples, the cause of infertility problems is attributed to men because of low sperm production and disturbed motility of sperm.
Afsane Ghasemi, Fatemehsadat Amjadi, Seyedeh Masoumeh Ghazi Mirsaeed, Robabeh Mohammad Beigi, Samaneh Ghasemi, Yousef Moradi, Seyedeh Tahereh Ghazi Mirsaeed   +6 more
doaj   +1 more source

Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls [PDF]

, 2007
Arabidopsis cell walls contain large amounts of pectins and hemicelluloses, which are predominantly synthesized via the common precursor UDP-glucuronic acid.
Klinghammer, Michaela, Tenhaken, Raimund
core   +1 more source

The Impact and Reliability of Tissue Segmentation on In Vivo Magnetic Resonance Spectroscopy Metabolite Quantification

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald, Kay Chioma Igwe, Antonia Kaiser, Karl Landheer, Jaimie Lee, John L. K. Kramer, Aaron T. Gudmundson, Helge J. Zöllner, Georg Oeltzschner, Candace C. Fleischer, Niklaus Zölch, Jamie Near, Mark Mikkelsen   +12 more
wiley   +1 more source

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli [PDF]

, 2010
The field of metabolic engineering has the potential to produce a wide variety of chemicals in both an inexpensive and ecologically-friendly manner. Heterologous expression of novel combinations of enzymes promises to provide new or improved synthetic ...
Dueber, John E., Moon, Tae Seok, Prather, Kristala L. Jones, Shiue, Eric Chun-Jen   +3 more
core   +1 more source

GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler, Roberto Souza, Ashley D. Harris   +2 more
wiley   +1 more source

Comparison of Efficacy between Myo-Inositol versus Metformin in Women with Polycystic Ovary Syndrome

Life and Science
Objective: To compare the effectiveness of myo-inositol versus metformin in treating women with polycystic ovary syndrome. Study Design: Cross-sectional study. Place and Duration of Study: The study was carried out at the Department of Gynae Unit II, Dr.
Nurmeen Latif, Seema Rajar, Mehreen Yousuf, Sadaf Imtiaz, Sidrah Abbas, Zara Jamali   +5 more
doaj   +1 more source

The SLC2 family of facilitated hexose and polyol transporters [PDF]

, 2018
The SLC2 family of glucose and polyol transporters comprises 13 members, the glucose transporters (GLUT) 1-12 and the H+-myo-inositol cotransporter (HMIT).
Thorens, Bernard, Uldry, Marc
core   +1 more source

Inositol, neural tube closure and the prevention of neural tube defects [PDF]

, 2016
Susceptibility to neural tube defects (NTDs), such as anencephaly and spina bifida is influenced by genetic and environmental factors including maternal nutrition.
Copp, AJ, Greene, ND, Leung, KY
core   +1 more source