Results 131 to 140 of about 41,135 (289)
Bovine Myoblast Differentiation
application/pdfSatellite cells are involved in postnatal myogenesis and in muscle hypertrophy. A better understanding of the mechanisms of myogenesis is useful to improve the muscle production in farm animals.
OHWADA, Shyuichi +5 more
core
Achieving myoblast engraftment into intact skeletal muscle via extracellular matrix
Cell therapy of skeletal muscles is a promising approach for the prevention of muscular diseases and age-related muscle atrophy. However, cell transplantation to treat muscle atrophy that does not involve disease, such as sarcopenia, is considered ...
Kitora Dohi +3 more
doaj +1 more source
Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress
Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan +8 more
wiley +1 more source
STIM1- and Orai1-dependent store-operated calcium entry regulates human myoblast differentiation
Our previous work on human myoblasts suggested that a hyperpolarization followed by a rise in [Ca(2+)](in) involving store-operated Ca(2+) entry (SOCE) channels induced myoblast differentiation. Advances in the understanding of the SOCE pathway led us to
Darbellay, Basile +6 more
core +1 more source
Dissection of Mitochondrial Function via Chemical Perturbation and Single‐Cell Profiling
We establish a systematic framework to dissect mitochondrial function at the module level by combining targeted chemical perturbations with scRNA‐seq. This approach reveals shared and module‐specific programs linking mitochondrial activity to mito‐nuclear communication, stress response, and cell cycle, highlighting the tight coupling between ...
Hao Luo +4 more
wiley +1 more source
Muscle development: Molecules of myoblast fusion
The fusion of myoblasts to make multinucleate muscle fibres is central to muscle development. Recent work on Drosophila has identified two members of the immunoglobulin superfamily that have key roles in controlling the specificity of myoblast ...
Taylor, Michael V., Michael V. Taylor
core +1 more source
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang +9 more
wiley +1 more source
The role of myostatin during postnatal myogenesis and sarcopenia
Myostatin, a TGF-β superfamily member, is a key negative regulator of embryonic and postnatal muscle growth. In order to further elucidate the role of myostatin during postnatal growth, several lines of investigation were undertaken in mice.
Siriett, Victoria Katherine
core
The effect of antiretrovirals on myoblast proliferation : migration and differentation. [PDF]
Thesis (M.Sc.)-University of KwaZulu-Natal, Westville, 2013.Successful antiretroviral (ARV) treatment is associated with suppression of HIV viral load and the reduction of clinical disease progression.
Sibanda, Wanani Nonhlanhla.
core
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang +7 more
wiley +1 more source

