Results 81 to 90 of about 78,749 (287)
Advanced Science, EarlyView.A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie +7 more
wiley +1 more source
Molecular Therapy: Methods & Clinical Development, 2020 We previously developed integrase-defective lentiviral vectors (IDLVs) as an antigen delivery system for inducing strong and prolonged immunity in animal models.
Yi-Yu Lin +8 more
doaj +1 more source
Akirin1 promotes myoblast differentiation by modulating multiple myoblast differentiation factors
Bioscience Reports, 2019 Abstract Akirin1 is found to be involved in myoblast differentiation. However, the mechanism by which the Akirin1 gene regulates myoblast differentiation still remains unclear. In the present study, we found that ectopic expression of Akirin1 promoted myoblast differentiation by increasing the expression of myogenic regulatory factor ...
Wenqiang Sun +9 more
openaire +2 more sources
Sestrins are evolutionarily conserved mediators of exercise benefits. [PDF]
, 2020 Exercise is among the most effective interventions for age-associated mobility decline and metabolic dysregulation. Although long-term endurance exercise promotes insulin sensitivity and expands respiratory capacity, genetic components and pathways ...
Brooks, Susan V +14 more
core +2 more sources
An incubatable direct current stimulation system for in vitro studies of Mammalian cells. [PDF]
, 2012 The purpose of this study was to provide a simplified alternative technology and format for direct current stimulation of mammalian cells. An incubatable reusable stimulator was developed that effectively delivers a regulated current and does not require
Caplan, Michael +3 more
core +2 more sources
Advanced Science, EarlyView.It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló +2 more
wiley +1 more source
Bioengineering & Translational MedicineA multifunctional bioreactor was fabricated in this study to investigate the facilitation efficiency of electrical and mechanical stimulations on myogenic differentiation.
Wei‐Wen Hu +4 more
doaj +1 more source
Analysis of platelet-derived growth factor receptor alpha expression in adult mouse testis
Journal of Animal Reproduction and BiotechnologyBackground: Platelet-derived growth factor receptor alpha (PDGFRα) is essential for various biological processes, including fetal Leydig cell differentiation.
Min Seok Woo +5 more
doaj +1 more source
Prostaglandin binding activity and myoblast fusion in aggregates of avian myoblasts
Developmental Biology, 1986 Myoblast aggregates provide a system for studying cell interactions which have several advantages over standard, stationary cultures. In gyrotory rotation, aggregate size can be controlled and is independent of cell migration. In muscle aggregates, fibroblasts are excluded, yet myoblast differentiation and fusion occur in a highly synchronous fashion ...
R E, Hausman +5 more
openaire +2 more sources
Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation. [PDF]
, 2020 Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant changes in its resident stem cells (i.e., satellite cells, SCs), differentiated cells (i.e., myofibers), and extracellular matrix cause a decline in tissue ...
Conboy, Irina M +4 more
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