Results 281 to 290 of about 107,803 (293)
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Estrogen-Mediated Protection in Myocardial Ischemia-Reperfusion Injury
Cardiovascular Toxicology, 2008Before menopause, a woman has a relatively low risk for developing cardiovascular disease. After menopause, however, the risk increases nearly twofold and cardiovascular disease remains the number one cause of death among women. Observational trials and studies in animal models of cardiovascular disease suggested that females have reduced injury after ...
Erin A, Booth, Benedict R, Lucchesi
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Polyamine metabolism in rat myocardial ischemia-reperfusion injury
International Journal of Cardiology, 2009This study was focused on investigating the involvement of polyamine metabolism in the myocardial ischemia-reperfusion injury (MIRI) in an in vivo rat model. A branch of the descending left coronary artery was occluded for 30 min followed by 2 h, 6 h, 12 h, and 24 h reperfusion. Then the expression of spermidine/spermine N1-acetyltransferase (SSAT) and
Liping, Han +5 more
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Glutamine Improves Myocardial Function following Ischemia-Reperfusion Injury
Asian Cardiovascular and Thoracic Annals, 2007Myocardial ischemia-reperfusion injury is common during cardiac procedures. Glutamine may protect the myocardium by preserving metabolic substrates. Glutamine (0.52 g·kg−1) or Ringer's lactate solution (control group) was administered intraperitoneally to 63 Sprague-Dawley rats at 4 or 18 hours prior to experimental ischemia and reperfusion.
Gil, Bolotin +5 more
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A Murine Model of Myocardial Ischemia–Reperfusion Injury
2018Ligation of the left anterior descending (LAD) coronary artery in the mouse heart is a widely used model to simulate myocardial infarction and ischemia-reperfusion injury. Here we describe a ligation technique routinely performed in our laboratory to induce myocardial infarction that may be used to study ischemia-reperfusion injury in the myocardium ...
Zhaobin, Xu +3 more
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Antioxidants and myocardial ischemia: reperfusion injuries.
Chang Gung medical journal, 2005Animal studies have demonstrated that restoration of blood flow to severely ischemic myocardium is a prerequisite for myocardial salvage. However, it has been shown that the restoration of blood flow to ischemic myocardium may be associated with deleterious changes of the myocardium, including arrhythmias, enzyme release, and contractile dysfunction ...
Jan-Kan, Chen, Shu-Er, Chow
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Trimetazidine ameliorates myocardial ischemia-reperfusion injury.
Pakistan journal of pharmaceutical sciences, 2019Aim of this study was to investigate the effects of trimetazidine attenuating the myocardial ischemia-reperfusion injury to myocardium in rats and the underlying mechanisms. A model of myocardial ischemia reperfusion was established via ligating the left anterior descending coronary artery in 30 rats, and then they were randomly assigned to model group
Chuanbo, He +5 more
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Statin and myocardial ischemia-reperfusion injury
International Journal of Cardiology, 2016Jun, Hu, Yao, Lu
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[Myocardial ischemia-reperfusion injury and melatonin].
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2006It is believed that myocardial ischemia-reperfusion injury is related to increased free radical generated and intracellular calcium overload especially during the period of reperfusion. The pineal secretory product, melatonin, is known to be a potent free radical scavenger, antioxidant and can inhibit the intracellular calcium overload. In this review,
Engin, Sahna +2 more
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Myocardial Protection Against Ischemia-Reperfusion Injury
2022Pasquale Pagliaro +2 more
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