Results 1 to 10 of about 100,764 (193)

Clinical and procedural predictors of suboptimal myocardial reperfusion in primary percutaneous coronary intervention [PDF]

International Journal of Cardiology: Heart & Vasculature, 2019
Background: Suboptimal myocardial perfusion in primary PCI is associated with increased infarct size, left ventricular (LV) dysfunction and higher mortality rates as compared as those with optimal myocardial perfusion.
Adel H. Mahmoud, Nasser M. Taha, Khaled Baraka, Mohamed Ashraf, Sayed Shehata   +4 more
doaj   +2 more sources

Magnetic susceptibility and R2* of myocardial reperfusion injury at 3T and 7T. [PDF]

Magn Reson Med, 2022
Moon BF, Iyer SK, Josselyn NJ, Hwuang E, Swago S, Keeney SJ, Castillero E, Ferrari G, Pilla JJ, Gorman JH, Gorman RC, Tschabrunn CM, Shou H, Matthai W, Wehrli FW, Ferrari VA, Han Y, Litt H, Witschey WR.   +18 more
europepmc   +3 more sources

Myocardial Reperfusion Injury

New England Journal of Medicine, 2007
Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M, Yellon, Derek J, Hausenloy
  +11 more sources

Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. [PDF]

PLoS ONE, 2014
Myocardial infarction resulting from ischemia-reperfusion injury can be reduced by cardiac postconditioning, in which blood flow is restored intermittently prior to full reperfusion.
Terrence Pong, Marielle Scherrer-Crosbie, Dmitriy N Atochin, Kenneth D Bloch, Paul L Huang   +4 more
doaj   +1 more source

Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

Bioactive Materials, 2022
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial infarction, but morbidity and mortality of acute myocardial infarction are still high.
Tianjiao Zhao, Wei Wu, Lihua Sui, Qiong Huang, Yayun Nan, Jianhua Liu, Kelong Ai   +6 more
doaj   +1 more source

Nrf2 Promotes Inflammation in Early Myocardial Ischemia-Reperfusion via Recruitment and Activation of Macrophages

Frontiers in Immunology, 2021
Cardiomyocyte apoptosis in response to inflammation is a primary cause of myocardial ischemia-reperfusion injury (IRI). Nuclear factor erythroid 2 like 2 (Nrf2) reportedly plays an important role in myocardial IRI, but the underlying mechanism remains ...
Haijian Zhang, Haijian Zhang, Yifei Liu, Xiaoqing Cao, Wenmiao Wang, Xiaohong Cui, Xuechao Yang, Yan Wang, Jiahai Shi, Jiahai Shi   +9 more
doaj   +1 more source

Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1

Cell Death Discovery, 2022
Myocardial ischemia/reperfusion (I/R) injury is a complex pathological process that is still not fully understood. The oxidative stress response has a critical role in the occurrence and progression of myocardial ischemia/reperfusion injury.
Qiong Xu, Mingke Liu, Jielei Gu, Sisi Ling, Xiaolin Liu, Zhenyu Luo, Yangshuo Jin, Renjie Chai, Wenchao Ou, Shiming Liu, Ningning Liu   +10 more
doaj   +1 more source

Electroacupuncture Pretreatment Mitigates Myocardial Ischemia/Reperfusion Injury via XBP1/GRP78/Akt Pathway

Frontiers in Cardiovascular Medicine, 2021
Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang, Jipeng Ma, Yan Ma, Linhe Lu, Chao Ma, Pei Qin, Erhe Gao, Mingzhang Zuo, Jian Yang, Lifang Yang   +9 more
doaj   +1 more source

Adenosine A2a Receptor Regulates Autophagy Flux and Apoptosis to Alleviate Ischemia-Reperfusion Injury via the cAMP/PKA Signaling Pathway

Frontiers in Cardiovascular Medicine, 2022
Exploring effective methods to lessen myocardial ischemia-reperfusion injury still has positive significance. The adenosine A2a receptor (A2aR) has played a crucial part in cardiac ischemia-reperfusion injury. Previous studies revealed that the adenosine
Yun Xia, Feng He, Mohamed Bassirou Moukeila Yacouba, Huimin Zhou, Jingfan Li, Ying Xiong, Jingjing Zhang, Hui Li, Yanlin Wang, Jianjuan Ke   +9 more
doaj   +1 more source

Heart defibrillation: relationship between pacing threshold and defibrillation probability

BioMedical Engineering OnLine, 2019
Background Considering the clinical importance of the ventricular fibrillation and that the most used therapy to reverse it has a critical side effect on the cardiac tissue, it is desirable to optimize defibrillation parameters to increase its efficiency.
Priscila C. Antoneli, Jair T. Goulart, Isabella Bonilha, Daniela D. de Carvalho, Pedro X. de Oliveira   +4 more
doaj   +1 more source