Results 271 to 280 of about 100,863 (292)
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ACUTE INTERVENTIONS FOR MYOCARDIAL REPERFUSION
Emergency Medicine Clinics of North America, 1998The primary goal of treatment in acute myocardial infarction is reperfusion of the infarct-related artery in as short a time as possible. Present strategies for acute reperfusion include the use of thrombolytic agents and a variety of catheter-based interventions.
M, Brown +3 more
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Lipid peroxidation during myocardial reperfusion
Molecular and Cellular Biochemistry, 1992Reperfusion of heart muscle after prolonged ischaemia is associated with metabolic and functional abnormalities and eventual cell death. Free radical induced lipid peroxidation of cell membranes is thought to be a major mechanism in the evolution of reperfusion damage. The evidences in support for this kind of damage are based on tissue malondialdehyde
CECONI, Claudio +5 more
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Bucillamine Prevents Myocardial Reperfusion Injury
Journal of Cardiovascular Pharmacology, 2001Injury during reperfusion can partially offset the benefit of relief of ischemia in myocardial infarctions rapidly treated with thrombolytic drugs or angioplasty. We assessed whether bucillamine (N-[2-mercapto-2-methylpropionyl]-L-cysteine) is potentially useful to treat myocardial reperfusion injury.
L D, Horwitz, N A, Sherman
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1999
Abstract Early in the history of cardiac surgery, it was recognized that some patients who underwent technically successful operations suffered from a syndrome of low cardiac output in the early postoperative period. It was also apparent that the perioperative mortality was increased in these patients. Autopsy and clinical studies in the
Robert C Gorman, Timothy J Gardner
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Abstract Early in the history of cardiac surgery, it was recognized that some patients who underwent technically successful operations suffered from a syndrome of low cardiac output in the early postoperative period. It was also apparent that the perioperative mortality was increased in these patients. Autopsy and clinical studies in the
Robert C Gorman, Timothy J Gardner
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Warm reperfusion and myocardial protection
The Annals of Thoracic Surgery, 1998The aim of this study was to determine whether warm reperfusion improves myocardial protection with cardiac troponin I as the criteria for evaluating the adequacy of myocardial protection.One hundred five patients undergoing first-time elective coronary bypass surgery were randomized to one of three cardioplegic strategies of either (1) cold ...
S, Chocron +9 more
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Myocardial postconditioning: reperfusion injury revisited
American Journal of Physiology-Heart and Circulatory Physiology, 2005coronary heart disease is the leading cause of death in the Western world and represents one of the major burdens on healthcare systems today. Targeting those strategies that limit the damage sustained as a result of a lethal ischemic insult has been a major goal for many years.
Andrew, Tsang +2 more
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Reperfusion in Acute Myocardial Infarction
Mayo Clinic Proceedings, 1990During the past decade, the general acceptance of the primary role of thrombosis in acute myocardial infarction (AMI) has led to intense interest in the potential efficacy of reperfusion therapy, particularly thrombolytic therapy, in AMI. Accumulating evidence indicates that systemic thrombolytic therapy administered early after the onset of symptoms ...
Lavie, C. J. +2 more
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Apoptosis in Myocardial Ischemia‐Reperfusion
Annals of the New York Academy of Sciences, 1999Abstract: The signal transduction pathways by which ischemia‐reperfusion leads to apoptosis may involve the JNK pathway, ceramide generation, and inhibition of protective PKC pathways. The biochemical events associated with apoptosis include mitochondrial inactivation, cytochrome c dislocation, caspase activation, and cytoplasmic acidification ...
R A, Gottlieb, R L, Engler
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[Myocardial reperfusion syndrome].
Archives des maladies du coeur et des vaisseaux, 1992Myocardial reperfusion is associated with a number of clinical, electrocardiographic (arrhythmias, conduction defects, ST segment changes), haemodynamic and biological events. The commonest arrhythmias are ventricular extra-systoles, rapid ventricular tachycardias, and accelerated idio-ventricular rhythms. Reperfusion bradycardias are less common. When
J P, Monassier +5 more
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Perioperative myocardial ischemia reperfusion injury
Anesthesiology Clinics of North America, 2003Myocardial I-R injury contributes to adverse cardiovascular outcomes after cardiac surgery. The pathogenesis of I-R injury is complex and involves the activation, coordination, and amplification of several systemic and local proinflammatory pathways (Fig. 4).
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