Results 1 to 10 of about 68,817 (283)

Lactated Ringer's solution for preventing myocardial reperfusion injury [PDF]

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2017
Reperfusion of ischemic myocardium is crucial for salvaging myocardial cells from ischemic cell death. However, reperfusion itself induces various deleterious effects on the ischemic myocardium.
Takashi Koyama
doaj   +2 more sources

Myocardial ischemia – reperfusion injury

open access: yesZaporožskij Medicinskij Žurnal, 2023
Aim. To summarize and broaden the idea about mechanisms of acute coronary insufficiency development and pathophysiological features of myocardial reperfusion injury.
S. V. Salo   +3 more
doaj   +2 more sources

S100A4-shRNA mitigates autophagy, reduces inflammation, and improves cardiac functionality in MIRI [PDF]

open access: yesInternational Journal of Cardiology. Cardiovascular Risk and Prevention
Background: S100A4 plays a crucial role in myocardial ischemia-reperfusion injury (MIRI), where the interplay between autophagy and inflammation shapes the progression of reperfusion injury.
Guangwei Huang   +5 more
doaj   +2 more sources

Electroacupuncture Pretreatment Mitigates Myocardial Ischemia/Reperfusion Injury via XBP1/GRP78/Akt Pathway

open access: yesFrontiers in Cardiovascular Medicine, 2021
Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang   +9 more
doaj   +1 more source

Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1

open access: yesCell Death Discovery, 2022
Myocardial ischemia/reperfusion (I/R) injury is a complex pathological process that is still not fully understood. The oxidative stress response has a critical role in the occurrence and progression of myocardial ischemia/reperfusion injury.
Qiong Xu   +10 more
doaj   +1 more source

Myocardial reperfusion injury [PDF]

open access: yesEuropean Heart Journal Supplements, 2002
Post-ischaemic reperfusion carries an injurious component that may partly counteract the beneficial effects of reflow; this component has been termed ‘reperfusion injury’. Principal mediators of this phenomenon are oxygen radicals and neutrophils. Oxygen radicals, generated in large amounts upon reflow, induce oxidative tissue damage and modulate ...
AMBROSIO, Giuseppe, TRITTO, Isabella
openaire   +2 more sources

Madder (Rubia cordifolia L.) Alleviates Myocardial Ischemia-Reperfusion Injury by Protecting Endothelial Cells from Apoptosis and Inflammation

open access: yesMediators of Inflammation, 2023
Objective. Ischemia-reperfusion injury often occurs in organ transplantation, coronary heart disease, ischemic heart disease, and other diseases, which greatly reduces clinical efficacy.
Jinwei Gao, Zheng Wang, Zhangzhang Ye
doaj   +1 more source

Adenosine A2a Receptor Regulates Autophagy Flux and Apoptosis to Alleviate Ischemia-Reperfusion Injury via the cAMP/PKA Signaling Pathway

open access: yesFrontiers in Cardiovascular Medicine, 2022
Exploring effective methods to lessen myocardial ischemia-reperfusion injury still has positive significance. The adenosine A2a receptor (A2aR) has played a crucial part in cardiac ischemia-reperfusion injury. Previous studies revealed that the adenosine
Yun Xia   +9 more
doaj   +1 more source

Opportunities and challenges of pain-related myocardial ischemia-reperfusion injury

open access: yesFrontiers in Physiology, 2022
Pain is one of the most serious problems plaguing human health today. Pain is not an independent pathophysiological condition and is associated with a high impact on elevated disability and organ dysfunction.
Wenhua Jiang   +5 more
doaj   +1 more source

Platelets in Myocardial Ischemia/Reperfusion Injury

open access: yesHämostaseologie, 2022
AbstractCoronary artery disease, including myocardial infarction (MI), remains a leading cause of global mortality. Rapid reperfusion therapy is key to the improvement of patient outcome but contributes substantially to the final cardiac damage. This phenomenon is called “ischemia/reperfusion injury (IRI).” The underlying mechanisms of IRI are complex ...
Schanze, Nancy   +4 more
openaire   +3 more sources

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